Abstract: A method of analyzing serial automated visual field data calculates a total field vector of the threshold sensitivity of points in a visual field and compares the total field vector with a calculated normal field vector for a given patient. The vector angle between the total field vector and the normal field vector is calculated to determine the distribution of threshold sensitivities to characterize the localization and the magnitude of field changes. In one embodiment, the sensitivities of each point in the visual field with respect to normal sensitivities for each point is plotted for each of a series of time spaced visual field tests. The single plot uses a line symmetrical about a zero axis whose magnitude reflects the difference from the norm for each point in each exam and forms a graphic depiction of changes in the visual field at each point over a series of visual field tests.

Abstract: A method for treating glaucoma in an eye of a human patient is disclosed. The method comprises the step of chronically, orally administering to the patient an unsaturated ketone derivative of an aryloxyacetic acid in an amount sufficient to safely and effectively lower intraocular pressure in the human eye. The unsaturated ketone derivative is selected from the group consisting of ethacrynic acid, an analog of ethacrynic acid, an ester derivative of ethacrynic acid, an ester derivative of an ethacrynic acid analog, an amide derivative of ethacrynic acid, an amide derivative of an ethacrynic acid analog, a pharmaceutically acceptable salt of ethacrynic acid, a pharmaceutically acceptable salt of an ethacrynic acid analog, a pharmaceutically acceptable salt of the ester derivative, a pharmaceutically acceptable salt of the amide derivative, and mixtures thereof. The amount administered is preferably between about 50 mg and about 75 mg two times per day.