Patents by Inventor Martin A. Folger
Martin A. Folger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9066955Abstract: Water soluble meloxicam granules include meloxicam, a salt forming agent which forms the meglumine, sodium, potassium, or ammonium salt of meloxicam, a binder, a sugar or sweetener, and a carrier, and a flavoring agent.Type: GrantFiled: March 13, 2013Date of Patent: June 30, 2015Assignee: Boehringer Ingelheim Vetmedica GmbHInventors: Stefan Henke, Martin A. Folger, Jens Lehmann, Diana C. Keilhofer, Hans-Juergen Kroff, Nina Herz
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Publication number: 20150064249Abstract: The invention is directed to a pharmaceutical tablet formulation for the veterinary medical sector containing an instable ACE inhibitor or a pharmaceutically acceptable salt thereof as a first pharmaceutically active substance, and pimobendan or a pharmaceutically acceptable salt thereof as a second pharmaceutically active substance, comprising granules which contain carrier core particles coated with at least one layer wherein the first pharmaceutically active substance is present, the granules being embedded in a tablet matrix wherein the second pharmaceutically active substance is present. It is provided a “fixed-dose-combination” which allows to ease the treatment and administration of the medication, improves the medication compliance by reducing the pill burden to the animal holder and enables the better observation of and adherence to the therapy by decreasing the number of tablets to be administered.Type: ApplicationFiled: March 14, 2013Publication date: March 5, 2015Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Martin Folger, Ragna Hoffmann, Florent Robin
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Publication number: 20150051198Abstract: An aqueous cyclodextrin-free solution of meloxicam suitable is provided for administration by needleless injection, containing a pharmacologically acceptable meloxicam salt of an organic or inorganic base and one or more suitable excipients.Type: ApplicationFiled: October 29, 2014Publication date: February 19, 2015Inventors: Martin A. Folger, Stefan Henke, Bernhard Hassel, Bernd Zierenberg
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Patent number: 8920820Abstract: An aqueous cyclodextrin-free solution of meloxicam suitable is provided for administration by needleless injection, containing a pharmacologically acceptable meloxicam salt of an organic or inorganic base and one or more suitable excipients.Type: GrantFiled: November 13, 2013Date of Patent: December 30, 2014Assignee: Boehringer Ingelheim Vetmedica GmbHInventors: Martin A. Folger, Stefan Henke, Bernhard Hassel, Bernd Zierenberg
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Publication number: 20140363510Abstract: A solid formulation includes pimobendan or a pharmaceutically acceptable salt thereof, which is homogenously dispersed with a polyvalent acid and a flavor suitable to animals.Type: ApplicationFiled: August 21, 2014Publication date: December 11, 2014Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Martin A. Folger, Bernhard Hassel, Stefan Henke, Jens Lehmann
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Publication number: 20140332438Abstract: A method of treating animals includes administering water soluble granules to an animal, where the water soluble granules include meloxicam, salt forming agent operable to form a meloxicam salt, a binder, and a carrier.Type: ApplicationFiled: July 28, 2014Publication date: November 13, 2014Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Stefan Henke, Martin A. Folger, Jens Lehmann, Diana C. Keilhofer, Hans-Juergen Kroff, Nina Herz
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Patent number: 8859554Abstract: A packaging assembly or kit includes packaging material containing a solid formulation including pimobendan dispersed in a polyvalent acid. The kit may also include a package leaflet or user instruction including the information concerning use of the solid formulation, for example, via the oral route for the prevention and/or treatment of congestive heart failure in a mammal in need of such prevention or treatment, preferably in a dog, cat or rodent.Type: GrantFiled: March 14, 2013Date of Patent: October 14, 2014Assignee: Boehringer Ingelheim Vetmedica GmbHInventors: Martin A. Folger, Bernhard Hassel, Stefan Henke, Jens Lehmann
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Patent number: 8846679Abstract: The invention relates to novel solid formulations comprising as pharmaceutically active compound pimobendan and to processes for producing such solid formulations. The invention furthermore relates to a method for manufacturing a medicament for the prevention and/or treatment of congestive heart failure, wherein the solid formulations according to the invention are used.Type: GrantFiled: March 4, 2005Date of Patent: September 30, 2014Assignee: Boehringer Ingelheim Vetmedica GmbHInventors: Martin A. Folger, Bernhard Hassel, Stefan Henke, Jens Schmalz
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Patent number: 8846680Abstract: The invention relates to novel solid formulations comprising as pharmaceutically active compound pimobendan and to processes for producing such solid formulations. The invention furthermore relates to a method for manufacturing a medicament for the prevention and/or treatment of congestive heart failure, wherein the solid formulations according to the invention are used.Type: GrantFiled: February 22, 2012Date of Patent: September 30, 2014Assignee: Boehringer Ingelheim Vetmedica GmbHInventors: Martin A. Folger, Bernhard Hassel, Stefan Henke, Jens Schmalz
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Publication number: 20140235648Abstract: A liquid preparation includes an etherified cyclodextrin derivative and a substituted benzimidazol, where the etherified cyclodextrin derivative is one of alpha-, beta, and gamma-cyclodextrin ether.Type: ApplicationFiled: April 25, 2014Publication date: August 21, 2014Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Martin FOLGER, Stefan LEHNER
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Publication number: 20140227351Abstract: Taste masked multi-layered particles include an inert core, one or more coating layer(s) comprising a pharmaceutically active ingredient and a binder, an intermediate coating layer (seal coating) free from a low molecular weight water-soluble ionic compound and including a water-soluble pharmaceutical film-forming compound selected from (i) HPMC and PEG or (ii) PVP, and an outer coating layer (final or taste masking coating) free from a low molecular weight water-soluble ionic compound and comprising (i) a poly(meth)acrylate or (ii) a mixture including 60-90% (w/w) EC and 10-40% (w/w) HPMC, where the pharmaceutically active ingredient is water-soluble and includes either at least one basic group and/or a bitter taste. Further disclosed are methods for the production of such particles and pharmaceutical compositions including such particles.Type: ApplicationFiled: April 16, 2014Publication date: August 14, 2014Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Martin FOLGER, Stefan LEHNER, Annette GRAVE, Norbet POELLINGER, Randolph SEIDLER
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Publication number: 20140224680Abstract: The present invention relates to a kit-of-parts, comprising A) a packaging (5), containing a defined amount of a pharmaceutically active ingredient in the form of solid coated one or multi-layered particles; B) a container (10), comprising a liquid oily composition to disperse or suspend the solid coated one or multi-layered particles contained in A); C) a dispenser (20); D) an adapter (50), having an application arrangement piece (55) with a through-hole (57) to fit the dispenser (20) to the container (10) of B); and E) instructions for use of the kit. The user just needs to mix and shake the components in order to produce a stable homogeneous mixture, which is: suited for exact dosing; stable and reusable; convenient to use; safe for the user due to omittance of needles; and has no injury risk for the user.Type: ApplicationFiled: February 10, 2014Publication date: August 14, 2014Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Martin FOLGER, Stefan LEHNER, Thomas Adam DUCH
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Patent number: 8741350Abstract: This application relates to taste masked multi-layered particles an inert core, one or more coating layer(s) comprising a pharmaceutically active ingredient and a binder, an intermediate coating layer (seal coating) free from a low molecular weight water-soluble ionic compound and comprising a water-soluble pharmaceutical film-forming compound selected from (i) HPMC and PEG or (ii) PVP, and an outer coating layer (final or taste masking coating) free from a low molecular weight water-soluble ionic compound and comprising (i) a poly(meth)acrylate or (ii) a mixture comprising 60-90% (w/w) EC and 10-40% (w/w) HPMC, wherein the pharmaceutically active ingredient is water-soluble and comprises either at least one basic group and/or a bitter taste. Further disclosed are methods for the production of such particles and pharmaceutical compositions comprising them.Type: GrantFiled: August 13, 2012Date of Patent: June 3, 2014Assignee: Boehringer Ingelheim Vetmedica GmbHInventors: Martin Folger, Stefan Lehner, Annette Grave, Norbert Poellinger, Randolph Seidler
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Publication number: 20140113893Abstract: An aqueous cyclodextrin-free solution of meloxicam suitable is provided for administration by needleless injection, containing a pharmacologically acceptable meloxicam salt of an organic or inorganic base and one or more suitable excipients.Type: ApplicationFiled: November 13, 2013Publication date: April 24, 2014Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Martin A. Folger, Stefan Henke, Bernhard Hassel, Bernd Zierenberg
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Publication number: 20140066440Abstract: A method for treating pain, inflammation, fever and respiratory complaints in mammals comprising administering by needleless injection to a mammal in need of such treatment an aqueous cyclodextrin-free solution of meloxicam containing a pharmacologically acceptable meloxicam salt of an organic or inorganic base.Type: ApplicationFiled: November 13, 2013Publication date: March 6, 2014Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Martin A. Folger, Stefan Henke, Bernhard Hassel, Bernd Zierenberg
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Publication number: 20130195977Abstract: A solid tablet formed through direct compression of powder, the powder comprising meloxicam as an active ingredient and one or more excipients which are homogenously dispersed within the tablet that can be broken into two, three or four units with each unit containing equal amounts of the meloxicam.Type: ApplicationFiled: March 13, 2013Publication date: August 1, 2013Applicant: Boehringer Ingelheim Vetmedica GmbHInventors: Martin A. Folger, Stefan Lehner, Horst Schmitt
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Publication number: 20130177613Abstract: A packaging assembly or kit includes packaging material containing a solid formulation including pimobendan dispersed in a polyvalent acid. The kit may also include a package leaflet or user instruction including the information concerning use of the solid formulation, for example, via the oral route for the prevention and/or treatment of congestive heart failure in a mammal in need of such prevention or treatment, preferably in a dog, cat or rodent.Type: ApplicationFiled: March 14, 2013Publication date: July 11, 2013Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Martin A. Folger, Bernhard Hassel, Stefan Henke, Jens Lehmann (nee Schmalz)
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Publication number: 20130178467Abstract: Aqueous cyclodextrin-free solution of meloxicam for administration by oral or parenteral route, containing a pharmacologically acceptable meloxicam salt of an organic or inorganic base and one or more suitable excipients, the content of dissolved meloxicam salt being more than 10 mg/mL. The formulation according to the invention has a shelf-life of up to 24 months or more.Type: ApplicationFiled: March 14, 2013Publication date: July 11, 2013Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Stefan Henke, Bernd Kruss, Bernhard Hassel, Hans-Juergen Kroff, Martin A. Folger, Klaus Daneck, Axel Prox
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Publication number: 20130161228Abstract: A plastic container containing a pharmaceutical composition comprising benzoic acid or a derivative or a pharmaceutically acceptable salt thereof and a COX-inhibitor of the oxicam-type or a pharmaceutical acceptable salt thereof, wherein the container material selected from one or more members of the group consisting of a homopolymer of polypropylene (PP), a copolymer of polypropylene (PP), a homopolymer of polyethylene terephthalate (PET) and a copolymer of polyethylene terephthalate (PET), and optionally one or more non-polymeric components.Type: ApplicationFiled: March 13, 2013Publication date: June 27, 2013Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Martin A. Folger, Samuel C. Crowley, Amy J. Wilson
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Publication number: 20130084332Abstract: This application relates to taste masked multi-layered particles an inert core, one or more coating layer(s) comprising a pharmaceutically active ingredient and a binder, an intermediate coating layer (seal coating) free from a low molecular weight water-soluble ionic compound and comprising a water-soluble pharmaceutical film-forming compound selected from (i) HPMC and PEG or (ii) PVP, and an outer coating layer (final or taste masking coating) free from a low molecular weight water-soluble ionic compound and comprising (i) a poly(meth)acrylate or (ii) a mixture comprising 60-90% (w/w) EC and 10-40% (w/w) HPMC, wherein the pharmaceutically active ingredient is water-soluble and comprises either at least one basic group and/or a bitter taste. Further disclosed are methods for the production of such particles and pharmaceutical compositions comprising them.Type: ApplicationFiled: August 13, 2012Publication date: April 4, 2013Applicant: BOEHRINGER INGELHEIM VETMEDICA GMBHInventors: Martin FOLGER, Stefan LEHNER, Annette GRAVE, Norbert POELLINGER, Randolph Seidler