Patents by Inventor Martin Diggelmann
Martin Diggelmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8389442Abstract: The use of fungicidal compounds of formula Ij wherein A and A? are both N or A and A? are both CH or A is CH and A? is N; j is 0 or 1 and the R groups are as defined in claim 1; their preparation and compositions 10 comprising the compounds.Type: GrantFiled: March 25, 2004Date of Patent: March 5, 2013Assignee: Syngenta Crop Protection LLCInventors: Peter Ackermann, Daniel Stierli, Martin Diggelmann, Fredrik Cederbaum, Jean Wenger, Ruud Titulaer
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Publication number: 20100292487Abstract: This invention relates to a process for the preparation of compounds of formula (I): where Ra, Rb, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are defined organic groups, the process comprising reaction a compound of formula (II): with a compound of formula (III): where Rc is as defined in relation to formula (I) followed by treatment with a base and cyclising the resulting adduct.Type: ApplicationFiled: August 15, 2006Publication date: November 18, 2010Applicant: SYNGENTA LIMITEDInventor: Martin Diggelmann
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Publication number: 20100035756Abstract: Compounds of formula (I), wherein the substituents are as defined in claim 1, are suitable for use as herbicides.Type: ApplicationFiled: July 10, 2007Publication date: February 11, 2010Applicants: SYNGENTA LIMITED, SYNGENTA CROP PROTECTION, INC.Inventors: Christoph Luthy, Roger Graham Hall, Andrew Edmunds, Suzanna Riley, Martin Diggelmann
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Publication number: 20070032490Abstract: The use of fungicidal compounds of formula Ij wherein A and A? are both N or A and A? are both CH or A is CH and A? is N; j is 0 or 1 and the R groups are as defined in claim 1; their preparation and compositions 10 comprising the compunds.Type: ApplicationFiled: March 25, 2004Publication date: February 8, 2007Inventors: Peter Ackermann, Daniel Stierli, Martin Diggelmann, Fredrik Cederbaum, Jean Wenger, Ruud Titulaer
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Patent number: 7060443Abstract: Methods for testing oligonucleotide arrays are disclosed including methods for testing the efficiency of nucleotide coupling; methods for testing amounts of deprotected oligonucleotides; methods for determining amounts of depurinated oligonucleotides; and methods of detecting the presence of cleavable structural features, such as double-stranded nucleic acids.Type: GrantFiled: June 10, 2003Date of Patent: June 13, 2006Assignee: Affymetrix, Inc.Inventors: Glenn McGall, Anthony D. Barone, Martin Diggelmann, David J. Lockhart, Ann Maria Caviani Pease, Mark Chee
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Publication number: 20050158744Abstract: Libraries of unimolecular, double-stranded oligonucleotides on a solid support. These libraries are useful in pharmaceutical discovery for the screening of numerous biological samples for specific interactions between the double-stranded oligonucleotides, and peptides, proteins, drugs and RNA. In a related aspect, the present invention provides libraries of conformationally restricted probes on a solid support. The probes are restricted in their movement and flexibility using double-stranded oligonucleotides as scaffolding. The probes are also useful in various screening procedures associated with drug discovery and diagnosis. The present invention further provides methods for the preparation and screening of the above libraries.Type: ApplicationFiled: November 19, 2004Publication date: July 21, 2005Applicants: Affymetrix, Inc., Affymax Technologies, N.V., a Netherlands Antilles corporationInventors: David Lockhart, Dirk Vetter, Martin Diggelmann
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Patent number: 6830890Abstract: Libraries of unimolecular, double-stranded oligonucleotides on a solid support. These libraries are useful in pharmaceutical discovery for the screening of numerous biological samples for specific interactions between the double-stranded oligonucleotides, and peptides, proteins, drugs and RNA. In a related aspect, the present invention provides libraries of conformationally restricted probes on a solid support. The probes are restricted in their movement and flexibility using double-stranded oligonucleotides as scaffolding. The probes are also useful in various screening procedures associated with drug discovery and diagnosis. The present invention further provides methods for the preparation and screening of the above libraries.Type: GrantFiled: October 22, 2002Date of Patent: December 14, 2004Assignee: Affymetrix, Inc.Inventors: David J. Lockhart, Dirk Vetter, Martin Diggelmann
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Publication number: 20040106728Abstract: New compounds, compositions and methods which find application in solid phase synthesis including the preparation of high-density arrays of diverse polymer sequences such as diverse peptides and oligonucleotides as well as in preparation of arrays of small ligand molecules. The compounds of the present invention are those which are typically referred to as linking groups, linkers or spacers and include unsymmetrical disulfide linking groups, and 1,3-diol derivatives capable of providing a triggered release of an attached compound from a solid support under mild conditions. Additional new compounds are labels which can be incorporated into either the 3′ or 5′ terminus of a DNA oligomer.Type: ApplicationFiled: July 14, 2003Publication date: June 3, 2004Applicant: Affymetrix, Inc.Inventors: Glenn H. McGall, Anthony D. Barone, Martin Diggelmann
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Publication number: 20040076987Abstract: Methods for testing oligonucleotide arrays are disclosed including methods for testing the efficiency of nucleotide coupling; methods for testing amounts of deprotected oligonucleotides; methods for determining amounts of depurinated oligonucleotides; and methods of detecting the presence of cleavable structural features, such as double-stranded nucleic acidsType: ApplicationFiled: June 10, 2003Publication date: April 22, 2004Applicant: Affymetrix, Inc.Inventors: Glenn McGall, Anthony D. Barone, Martin Diggelmann, David J. Lockhart, Ann Maria Caviani Pease, Mark Chee
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Patent number: 6576425Abstract: Methods for testing oligonucleotide arrays are disclosed including methods for testing the efficiency of nucleotide coupling; methods for testing amounts of deprotected oligonucleotides; methods for determining amounts of depurinated oligonucleotides; and methods of detecting the presence of cleavable structural features, such as double-stranded nucleic acids.Type: GrantFiled: February 8, 2001Date of Patent: June 10, 2003Assignee: Affymetrix, Inc.Inventors: Glenn McGall, Anthony D. Barone, Martin Diggelmann, David J. Lockhart, Ann Maria Caviani Pease, Mark Chee
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Publication number: 20030049674Abstract: Libraries of unimolecular, double-stranded oligonucleotides on a solid support. These libraries are useful in pharmaceutical discovery for the screening of numerous biological samples for specific interactions between the double-stranded oligonucleotides, and peptides, proteins, drugs and RNA. In a related aspect, the present invention provides libraries of conformationally restricted probes on a solid support. The probes are restricted in their movement and flexibility using double-stranded oligonucleotides as scaffolding. The probes are also useful in various screening procedures associated with drug discovery and diagnosis. The present invention further provides methods for the preparation and screening of the above libraries.Type: ApplicationFiled: October 22, 2002Publication date: March 13, 2003Applicant: Affymetrix, Inc.Inventors: David J. Lockhart, Dirk Vetter, Martin Diggelmann
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Patent number: 6482591Abstract: Libraries of unimolecular, double-stranded oligonucleotides on a solid support. These libraries are useful in pharmaceutical discovery for the screening of numerous biological samples for specific interactions between the double-stranded oligonucleotides, and peptides, proteins, drugs and RNA. In a related aspect, the present invention provides libraries of conformationally restricted probes on a solid support. The probes are restricted in their movement and flexibility using double-stranded oligonucleotides as scaffolding. The probes are also useful in various screening procedures associated with drug discovery and diagnosis. The present invention further provides methods for the preparation and screening of the above libraries.Type: GrantFiled: April 3, 1998Date of Patent: November 19, 2002Assignee: Affymetrix, Inc.Inventors: David J. Lockhart, Dirk Vetter, Martin Diggelmann
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Publication number: 20020016008Abstract: Libraries of unimolecular, double-stranded oligonucleotides on a solid support. These libraries are useful in pharmaceutical discovery for the screening of numerous biological samples for specific interactions between the double-stranded oligonucleotides, and peptides, proteins, drugs and RNA. In a related aspect, the present invention provides libraries of conformationally restricted probes on a solid support. The probes are restricted in their movement and flexibility using double-stranded oligonucleotides as scaffolding. The probes are also useful in various screening procedures associated with drug discovery and diagnosis. The present invention further provides methods for the preparation and screening of the above libraries.Type: ApplicationFiled: April 3, 1998Publication date: February 7, 2002Inventors: DAVID J. LOCKHART, DIRK VETTER, MARTIN DIGGELMANN
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Publication number: 20020009729Abstract: Methods for testing oligonucleotide arrays are disclosed including methods for testing the efficiency of nucleotide coupling; methods for testing amounts of deprotected oligonucleotides; methods for determining amounts of depurinated oligonucleotides; and methods of detecting the presence of cleavable structural features, such as double-stranded nucleic acids.Type: ApplicationFiled: February 8, 2001Publication date: January 24, 2002Applicant: Affymetrix, Inc.Inventors: Glenn McGall, Anthony D. Barone, Martin Diggelmann, David J. Lockhart, Ann Maria Caviani Pease, Mark Chee
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Patent number: 6238862Abstract: Methods for testing oligonucleotide arrays are disclosed including methods for testing the efficiency of nucleotide coupling; methods for testing amounts of deprotected oligonucleotides; methods for determining amounts of depurinated oligonucleotides; and methods of detecting the presence of cleavable structural features, such as double-stranded nucleic acids.Type: GrantFiled: December 19, 1997Date of Patent: May 29, 2001Assignee: Affymetrix, Inc.Inventors: Glenn McGall, Anthony D. Barone, Martin Diggelmann, David J. Lockhart, Ann Maria Caviani Pease, Mark Chee
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Patent number: 5770722Abstract: Libraries of unimolecular, double-stranded oligonucleotides on a solid support. These libraries are useful in pharmaceutical discovery for the screening of numerous biological samples for specific interactions between the double-stranded oligonucleotides, and peptides, proteins, drugs and RNA. In a related aspect, the present invention provides libraries of conformationally restricted probes on a solid support. The probes are restricted in their movement and flexibility using double-stranded oligonucleotides as scaffolding. The probes are also useful in various screening procedures associated with drug discovery and diagnosis. The present invention further provides methods for the preparation and screening of the above libraries.Type: GrantFiled: June 13, 1996Date of Patent: June 23, 1998Assignee: Affymetrix, Inc.Inventors: David J. Lockhart, Dirk Vetter, Martin Diggelmann
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Patent number: 5556752Abstract: Libraries of unimolecular, double-stranded oligonucleotides on a solid support. These libraries are useful in pharmaceutical discovery for the screening of numerous biological samples for specific interactions between the double-stranded oligonucleotides, and peptides, proteins, drugs and RNA. In a related aspect, the present invention provides libraries of conformationally restricted probes on a solid support. The probes are restricted in their movement and flexibility using double-stranded oligonucleotides as scaffolding. The probes are also useful in various screening procedures associated with drug discovery and diagnosis. The present invention further provides methods for the preparation and screening of the above libraries.Type: GrantFiled: October 24, 1994Date of Patent: September 17, 1996Assignee: Affymetrix, Inc.Inventors: David J. Lockhart, Dirk Vetter, Martin Diggelmann