Abstract: The present invention relates to methods for diagnosing, staging and treating cancer, in particular melanoma. In particular, the present invention provides methods for determining the stage/type of a cancerous disease, comprising detecting somatic alterations of the DNA of one or more disseminated cancer cells (DCCs), obtained after homing to a distant organ, such as lymph node; and determining the somatic evolution of the DCC(s) based on the detected somatic alterations, wherein the somatic evolution is indicative of the stage/type of the cancerous disease.

Abstract: The invention relates to a light emitting device comprising a light source array which comprises a plurality of separately electrically controllable electric light sources which are arranged in a matrix structure or any other defined geometrical arrangement. Advantageously, the pixel pitch of the light source array is less than (500) nanometer. The invention further relates to an optical detection device comprising a light detection device, which is arranged for producing an electrical signal in response to light reaching a light detection side of the light detection device, and to a method for operating such an optical detection device. The invention further relates to a computer program with program coding means arranged for performing such a method.

Abstract: Various embodiments of system and methods of creating a filter for a list of objects are described herein. The method includes receiving a selection of a set of objects from the list of objects composed of one or more fields having field values, and comparing the field value in each field of an object with the field values in each of the corresponding fields of the other objects in the set of objects. Based on the comparison, identifying that the field values are the same across the one or more fields of the set of objects. The method further includes generating a list of filter criteria based on the identified field values. The filter may be created using the list of filter criteria.

Abstract: The present invention relates to a hair treatment process wherein an aqueous composition comprising one or more cationic polymers having certain cationic change density is applied onto hair and without rinsing off the temperature of the hair is increased. The novel treatment process allows consumers to a long lasting conditioning of their hair.

Abstract: The present invention relates to an aqueous composition for treating hair comprising one or more cationic polymers having certain cationic change density and one or more of nonionic surfactants. The novel composition provides hair long lasting conditioning, especially improves combability and suppleness of hair which is held up to 20 hair washes.

Abstract: The present invention is related to an aqueous cleansing composition for keratin fibres, especially human hair, comprising at least two anionic surfactants comprising at least one amide group in their molecules. The first object of the present invention is an aqueous cleansing composition comprising at least two anionic surfactants comprising at least one amide group in their molecules and substantially frees of alkyl sulphate and alkyl ether sulphate surfactants. The two anionic surfactants comprising at least one amide group in their molecule is preferably selected from surfactants of the following structure wherein R1 is a saturated or unsaturated, straight or branched alkyl chain with 7 to 17 C atoms, R2 is H or a methyl, R3 is H, COO?M+, CH2COO?M or COOH, n is 0 to 2, X is COO? or SO3? and M is independent from each other H, sodium or potassium. The cleasning composition comprise furthermore amphoteric and non-ionic surfactants.

Abstract: A sea water cooling system including a first fluid cooling loop coupled to a first side of a heat exchanger and to a thermal load, a second fluid cooling loop coupled to a second side of the heat exchanger and including a pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the pump, wherein the controller is configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the pump based on the monitored temperature to achieve a predetermined temperature in the first fluid cooling loop. The system may be selectively operable in one of a plurality of operating modes, wherein in a first operating mode the pump operates based entirely on cooling demands of the thermal load, and in a second operating mode the pump operates to maintain a fluid pressure above a predefined pressure.

Abstract: A sea water cooling system including a first fluid cooling loop coupled to a first side of a heat exchanger and to a thermal load, a second fluid cooling loop coupled to a second side of the heat exchanger and including a pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the pump, wherein the controller is configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the pump based on the monitored temperature to achieve a predetermined temperature in the first fluid cooling loop. The system may be selectively operable in one of a plurality of operating modes, wherein in a first operating mode the pump operates based entirely on cooling demands of the thermal load, and in a second operating mode the pump operates to maintain a fluid pressure above a predefined pressure.

Abstract: The invention relates to a light emitting device comprising a light source array which comprises a plurality of separately electrically controllable electric light sources which are arranged in a matrix structure or any other defined geometrical arrangement. Advantageously, the pixel pitch of the light source array is less than (500) nanometer. The invention further relates to an optical detection device comprising a light detection device, which is arranged for producing an electrical signal in response to light reaching a light detection side of the light detection device, and to a method for operating such an optical detection device. The invention further relates to a computer program with program coding means arranged for performing such a method.

Abstract: The present invention relates to an aqueous composition for treating hair comprising one or more cationic polymers having certain cationic change density and one or more aminated silicones. The novel composition provides hair long lasting conditioning, especially improves combability and suppleness of hair which is held up to 20 hair washes.

Abstract: An active roll stabilizer of a motor vehicle including an actuator (8) in the form of a swivel motor arranged so as to rotate about a longitudinal axis of the vehicle. The swivel motor has an essentially cylindrical housing (12) with a cover, first and second stabilizer halves (18, 19) are connected to respective ends of the actuator for the transmission of torque, and a wiring harness (1) has a first end and a second end. The harness includes cables (3, 4, 5) for the transmission of electric power and signals. The first end is connected to the actuator, by way of a plug (2), and the second end is arranged positionally fixed in the vehicle at a cable transfer point (20). The cover forms a dry space and has a plug receiving opening, in its periphery, into which the plug can be inserted, in the radial direction, and secured.

Abstract: An electric roll control stabilizer for a vehicle, having an outer housing that rotates about a longitudinal axis, a wiring harness has at least one electric supply lead and/or electric control lead is connected at its first end to a first connection terminal provided on the outer housing and at its second end to a second fixed in position connection terminal. In an area of the first terminal, the harness extends tangential to or concentrical with an outer enveloping surface of the outer housing or a cylindrical structural element which is attached rotationally fixed and whose outer diameter is smaller than the diameter of the outer housing. From the area of the first terminal, the wiring harness extends concentrically with and is spaced from the outer enveloping surface, and the wiring harness is arranged in a transverse plane of the outer housing or the cylindrical structural element that passes through the first terminal.

Abstract: An electric motor comprising a rotor which has a plurality of permanent magnets arranged along a circumferential direction, a stator arrangement with a winding arrangement which surrounds, at least in parts, the permanent magnets. Said stator arrangement comprises a first stator having a plurality of windings and the stator arrangement comprises a second stator, the windings of the first and second stators being embodied, respectively as frame-shaped coils, said coils of the first stator being arranged in the radial direction on the outside of the permanent magnets, the coils of the second stator being arranged in the radial direction inside the permanent magnets, and the coils are arranged along the winding axis thereof in the radial direction and the permanent magnets are arranged along the magnetization direction thereof in the radial direction.

Abstract: An intelligent sea water cooling system including a first fluid cooling loop coupled to a heat exchanger, a second fluid cooling loop coupled to the heat exchanger and including a fluid pump for circulating fluid through the second fluid cooling loop, and a controller operatively connected to the fluid pump. The controller may be configured to monitor an actual temperature in the first fluid cooling loop and to adjust a speed of the fluid pump based on the monitored temperature in order to achieve a desired temperature in the first fluid cooling loop.

Abstract: A laser source that generates an optical frequency comb, comprising a pumped laser medium placed inside an optical cavity that incorporates at least one optically-controlled modulator, a detector generating an error signal, and a modulation optical source that is controlled by the error signal and whose radiation is directed onto said optically-controlled modulator thereby stabilizing the Carrier-Envelope Offset (CEO) frequency and/or the CEO phase and/or the repetition rate of said source.

Abstract: An electromechanical actuating drive (1) having a servomotor (2) arranged so that the servomotor (2) can rotate about its longitudinal axis in a vehicle, and a cable harness (3) having first and second ends. A first end of the harness (3) is connected to the servomotor (2) and the harness (3) extends, in an elastically deformable arc, from the first end to the second end. The second end of the harness (3) is positionally fixed in the vehicle. The second end of the cable harness (3) is clamped in a securing and deflecting device at a transfer point (5).

Abstract: An electromechanical actuator having an electric motor which comprises a rotor shaft (5) and a motor housing (2). A bearing plate (6) is supported inside the motor housing (2) for holding the rotor shaft (5). A cover (3) is arranged in front of the motor housing (2) and the bearing plate (6) and is connected to a stabilizer half (4). A component carrier (8) is arranged on and fixed to the bearing plate (6) for supporting electric and/or electronic components.

Abstract: The present invention relates to a conditioning composition for keratin fibres especially human hair comprising particular cationic polymers and a cationic silicone compound. The present inventor has surprisingly found out that an aqueous hair conditioning composition comprising at least two cationic polymers, one being a cationic polymer with multiple cationic sites and with multiple ester groups in its molecule and the other cationic polymer is being a cellulose derivative, and a cationic or cationizable silicone improves hair combability, smoothness shine, elasticity and more interestingly hair treated with such a composition has volume and body and excellently manageable.

Abstract: Processes wash out less color from artificially colored hair and comprise artificially coloring hair by applying a dye composition, comprising at least one hair dye, onto the hair, rinsing the dye composition off from the artificially colored hair, improving color stability of the artificially colored hair by washing the artificially colored hair, one or more times, with an aqueous cleansing composition, and drying the artificially colored hair or leaving the artificially colored hair to dry. The aqueous cleansing composition comprises at least three anionic surfactants and at least one non-ionic surfactant mixed together in water and is free of amphoteric surfactants.

Abstract: The present invention is related to an aqueous conditioning composition for hair comprising at least one alkyl ether alkyl amine or alkyl ether alkyl quaternary amine and at least one compound selected from fatty acid fatty alcohol esters and arylated silicones.