Abstract: A method for monitoring a biotechnological process, wherein starting materials are converted into products via a biomass and important process parameters for monitoring are identified during the process, where during the process, a current concentration of the biomass utilized in the process is recurrently estimated, current measurement values of measurable process parameters are then recurrently determined on a recurring basis and current values for additional process parameters are identified therefrom, where the current measurement values of the measurable process parameters and the current determined values of the additional process parameters are based on the respective temporally correlating concentration of biomass and where, from a combination of the current concentration of biomass and the current measurement values of the measurable process parameters and the identified current values of the additional process parameters, current, cell-specific metabolic indicators are then derived which are then us

Abstract: Disclosed is a potentiometric rod-shaped measuring chain for determining the pH value, comprising a measuring half-cell with a measuring electrode (1) and a reference half-cell with at least one reference electrode (2). In order to be able to carry out a functional check of the measuring chain during the pH measurement, provision is made for a voltammetric measuring cell with a working electrode (4) and a counterelectrode (5) to be additionally provided for the purpose of checking the potential measurement of the measuring chain, wherein the voltammettic measuring cell is connected to a voltammetric evaluation unit.

Abstract: Disclosed is a sensor device (100) for the parallel determination of a concentration of small molecule substances (e.g. ethanol, glucose, etc.) and of a pH value in a solution during the course of a biotechnological process using what is known as cyclic voltammetry. Said sensor device is constructed in the form of a rod electrode. The sensor device consists at least of two rod-shaped working electrodes (102, 103), for which different conductive materials are selected in such a way that distinguishable voltage/current profiles can be determined for the small molecule substances to be determined, and of a rod-shaped reference electrode (104). The working electrodes and the reference electrode are each embedded or melted in a tubular, insulating material. Furthermore, the sensor device comprises a counter electrode (105) in the form of a hollow cylinder, within which the working electrodes and the reference electrode are mounted.

Abstract: A method of monitoring bioprocesses, wherein a course of a bioprocess is predicted using a process model and values for process parameters are estimated during the bioprocess, where at least one process parameter is selected (step a), for which current measured values are determined during the bioprocess, the respective current measured value of the selected process parameter is compared with the corresponding estimated value for this process parameter estimated by the process model (step b), a variance is then compared with a predetermined threshold value (step c), in a step d), at least one model parameter is then changed when the threshold value is exceeded by the variance, where steps b) to d) are executed until the variance fails to meet the threshold value, and in the case that the threshold value is not met after a predetermined number of repetitions, the method is discontinued and a warning is output.

Abstract: Method and system for creating and implementing a cleaning-in-place installation cleaning process for a process installation, wherein an installation to be cleaned is represented as process modules that each include an item of self-description information with respect to the respective cleaning properties and that are each configured to transmit the self-description information, where the system has at least one auxiliary module that provides auxiliary services for the installation cleaning process, and a process planning unit that has an item of cleaning process information having cleaning steps needed at least for the installation cleaning process and model descriptions of cleaning efficiency for each cleaning step, and the process planning unit determines a cleaning schedule in a partially automated manner on a system-specific basis based on the cleaning process information supplemented with self-description information relating to the process modules and taking into account information relating to the at

Abstract: A method for monitoring a biotechnological process, wherein starting materials are converted into products via a biomass and important process parameters for monitoring are identified during the process, where during the process, a current concentration of the biomass utilized in the process is recurrently estimated, current measurement values of measurable process parameters are then recurrently determined on a recurring basis and current values for additional process parameters are identified therefrom, where the current measurement values of the measurable process parameters and the current determined values of the additional process parameters are based on the respective temporally correlating concentration of biomass and where, from a combination of the current concentration of biomass and the current measurement values of the measurable process parameters and the identified current values of the additional process parameters, current, cell-specific metabolic indicators are then derived which are then us

Abstract: A method of monitoring bioprocesses, wherein a course of a bioprocess is predicted using a process model and values for process parameters are estimated during the bioprocess, where at least one process parameter is selected (step a), for which current measured values are determined during the bioprocess, the respective current measured value of the selected process parameter is compared with the corresponding estimated value for this process parameter estimated by the process model (step b), a variance is then compared with a predetermined threshold value (step c), in a step d), at least one model parameter is then changed when the threshold value is exceeded by the variance, where steps b) to d) are executed until the variance fails to meet the threshold value, and in the case that the threshold value is not met after a predetermined number of repetitions, the method is discontinued and a warning is output.

Abstract: The invention relates to a method and an arrangement for determining the composition of a multiphase mixture (MG), the multiphase mixture (MG) having at least three phases, in particular mineral oil, water, sand and/or sludge. The multiphase mixture (MG) is conveyed away or led from a delivery point, for example, in a through-flow device (DF), in particular a pipeline. At least two electrodes (E1, E2) for the capacitive management of an impedance (Zx) of the multiphase mixture (MG) are fitted to the through-flow device (DF) so as to be insulated electrically from the multiphase mixture (MG), and a changing electric voltage having a defined amplitude is applied to the multiphase mixture (MG) by a voltage source (VQ), wherein a frequency of said voltage can be adjusted. Then, with the aid of a reference impedance (Zref), a capacitive measurement of the impedance (Zx) of the multiphase mixture (MG) is carried out (2) via the electrodes (E1, E2).

Abstract: The present invention pertains to a process for purifying the exhaust air from plant parts of oil mills, in which the exhaust air removed from the plant is returned, after part of it had been discharged, into the plant in a cycle.