Patents by Inventor Martin L. Kantor
Martin L. Kantor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6558706Abstract: This invention provides an encapsulated fragrance in which the fragrance is controlled can be released by exposing the encapsulated fragrance to a solution of a predetermined pH. The invention also contemplates a process for preparing encapsulated fragrances.Type: GrantFiled: January 31, 2002Date of Patent: May 6, 2003Assignee: Emisphere Technologies, Inc.Inventors: Martin L. Kantor, Evgueni Barantsevitch, Sam J. Milstein
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Publication number: 20030042638Abstract: Methods for preparing microspheres containing imidazole derivatives are provided. Also provided is the use of imidazole derivatives containing microspheres for treating fungal infections. Oral dosage forms for oral administration are also provided.Type: ApplicationFiled: August 15, 2002Publication date: March 6, 2003Inventor: Martin L. Kantor
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Patent number: 6461545Abstract: Methods for preparing microspheres containing imidazole derivatives are provided. Also provided is the use of imidazole derivatives containing microspheres for treating fungal infections. Oral dosage forms for oral administration are also provided.Type: GrantFiled: January 6, 2000Date of Patent: October 8, 2002Assignee: Emisphere Technologies, Inc.Inventor: Martin L. Kantor
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Publication number: 20020102286Abstract: This invention provides an encapsulated fragrance in which the fragrance is controlled can be released by exposing the encapsulated fragrance to a solution of a predetermined pH. The invention also contemplates a process for preparing encapsulated fragrances.Type: ApplicationFiled: January 31, 2002Publication date: August 1, 2002Applicant: Emisphere Technologies, Inc.Inventors: Martin L. Kantor, Evgueni Barantsevitch, Sam J. Milstein
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Patent number: 6413550Abstract: Improved proteinoid carriers and methods for their preparation and use as oral delivery systems for pharmaceutical agents are described. The proteinoid carriers are soluble within selected pH ranges within the gastrointestinal tract and display enhanced stability towards at least one of photolysis or decomposition over time. The proteinoid carriers are prepared from proteinoids having between 2 and 20 amino acids and having a molecular weight of between about 250 and 2400 daltons.Type: GrantFiled: November 23, 1998Date of Patent: July 2, 2002Assignee: Emisphere Technologies, Inc.Inventors: Sam J. Milstein, Martin L. Kantor
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Patent number: 6375983Abstract: This invention provides an encapsulated fragrance in which the fragrance is controlled can be released by exposing the encapsulated fragrance to a solution of a predetermined pH. The invention also contemplates a process for preparing encapsulated fragrances.Type: GrantFiled: June 12, 1997Date of Patent: April 23, 2002Assignee: Emisphere Technologies, Inc.Inventors: Martin L. Kantor, Evgueni Barantsevitch, Sam J. Milstein
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Patent number: 6100285Abstract: Solutions comprising itraconazole solubilized in a solvent comprising at least one volatile organic acid are provided. Methods for preparing microspheres containing imidazole derivatives are provided. Also provided is the use of imidazole derivatives containing microspheres for treating fungal infections. Oral dosage forms for oral administration are also provided.Type: GrantFiled: November 11, 1997Date of Patent: August 8, 2000Assignee: Emisphere Technologies, Inc.Inventor: Martin L. Kantor
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Patent number: 6051258Abstract: The present invention provides emulsions, and a method for preparing emulsions, comprising (A) an aqueous phase, (B) an non-aqueous phase, and (C) (i) a proteinoid emulsifier, (ii) a modified hydrolyzed vegetable protein emulsifier wherein said modified hydrolyzed vegetable protein is modified with an amine reactive modifying agent, (iii) an acylated non-.alpha.-amino acid emulsifier, (iv) an acylated poly amino acid emulsifier, (v) an acylated peptide emulsifier, (vi) a sulfonated non-.alpha.-amino acid emulsifier, (vii) a sulfonated poly amino acid emulsifier, (viii) a sulfonated peptide emulsifier, or (ix) any combination of any of (i), (ii), (iii), (iv), (v), (vi), (vii), and (viii). The proteinoids, modified hydrolyzed vegetable proteins, modified non-.alpha.-amino acids, modified poly amino acids, and modified peptides used in the present invention provide emulsions having improved stability against degradation and/or decomposition.Type: GrantFiled: June 7, 1995Date of Patent: April 18, 2000Assignee: Emisphere Technologies, Inc.Inventor: Martin L. Kantor
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Patent number: 5840340Abstract: Improved proteinoid carriers and methods for their preparation and use as oral delivery systems for pharmaceutical agents are described. The proteinoid carriers are soluble within selected pH ranges within the gastrointestinal tract and display enhanced stability towards at least one of photolysis or decomposition over time. The proteinoid carriers are prepared from proteinoids having between 2 and 20 amino acids and having a molecular weight of between about 250 and 2400 daltons.Type: GrantFiled: August 30, 1996Date of Patent: November 24, 1998Assignee: Emisphere Technologies, Inc.Inventors: Sam J. Milstein, Martin L. Kantor
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Patent number: 5750147Abstract: Methods for preparing microspheres containing imidazole derivatives are provided. Also provided is the use of imidazole derivatives containing microspheres for treating fungal infections. Oral dosage forms for oral administration are also provided.Type: GrantFiled: June 7, 1995Date of Patent: May 12, 1998Assignee: Emisphere Technologies, Inc.Inventor: Martin L. Kantor
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Patent number: 5667806Abstract: Methods for preparing microspheres are provided. A carrier vehicle and a precipitator are nebulized and contacted. Alternatively, a carrier is nebulized in an aqueous acid and the concentration of the acid is decreased. Apparatus are also provided.Type: GrantFiled: June 7, 1995Date of Patent: September 16, 1997Assignee: Emisphere Technologies, Inc.Inventor: Martin L. Kantor
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Patent number: 5601846Abstract: Improved proteinoid micropheres and methods for their preparation and use as oral delivery systems for pharmaceutical agents are described. The proteinoid microspheres are soluble within selected pH ranges within the gastrointestinal tract and display enhanced stability towards least one of photolysis or decomposition over time. The proteinoid microspheres are prepared from proteinoids having between 2 and 8 amino acids and having a molecular weight of about 1000 daltons.Type: GrantFiled: May 9, 1995Date of Patent: February 11, 1997Assignee: Emisphere Technologies, Inc.Inventors: Sam J. Milstein, Martin L. Kantor
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Patent number: 5578323Abstract: Improved proteinoid carriers and methods for their preparation and use as oral delivery systems for pharmaceutical agents are described. The proteinoid carriers are soluble within selected pH ranges within the gastrointestinal tract and display enhanced stability towards at least one of photolysis or decomposition over time. The proteinoid carriers are prepared from proteinoids having between 2 and 20 amino acids and having a molecular weight of between about 250 and 2400 daltons.Type: GrantFiled: June 14, 1993Date of Patent: November 26, 1996Assignee: Emisphere Technologies, Inc.Inventors: Sam J. Milstein, Martin L. Kantor
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Patent number: 5443841Abstract: Improved proteinoid microspheres and methods for their preparation and use as oral delivery systems for pharmaceutical agents are described. The proteinoid microspheres are soluble within selected pH ranges within the gastrointestinal tract and display enhanced stability towards at least one of photolysis or decomposition over time. The proteinoid microspheres are prepared from proteinoids having between 2 and 8 amino acids and having a molecular weight of about 1000 daltons.Type: GrantFiled: July 27, 1992Date of Patent: August 22, 1995Assignee: Emisphere Technologies, Inc.Inventors: Sam J. Milstein, Martin L. Kantor
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Patent number: 4895725Abstract: Microcapsules containing oil-based biologically active compounds which are stable over extended time periods for release of the encapsulated compound in the intestine. There are a number of biologically active compounds having an oil base which must be orally ingested in order to have a beneficial effect. An example of one such biologically active oil-based compound is a fish oil having a high content of polyunsaturated omega-3 fatty acids which has been demonstrated to reduce plasma levels of triglycerides, very low density lipoprotein, low density lipoproteins and cholesterol in normal and hyperlipidemic subjects. The disclosed microcapsules eliminate the unfortunate problems of the unpleasant taste and smell of the fish oil, as well as the aftertaste, particularly when ingested in large quantities, and provide a palatable and practical means of ingesting efficacious quantities of fish oil. In addition, the normal oxidation of polyunsaturated fatty acids is inhibited.Type: GrantFiled: April 4, 1988Date of Patent: January 23, 1990Assignee: Clinical Technologies Associates, Inc.Inventors: Martin L. Kantor, Solomon S. Steiner, Howard M. Pack
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Patent number: 4681973Abstract: Acylated amino acids having the general formula ##STR1## are prepared by reacting a compound of formula II ##STR2## with a compound of formula IIIROCOClwherein R, R.sub.1, R.sub.2 and R.sub.3 are as defined herein.Type: GrantFiled: February 27, 1986Date of Patent: July 21, 1987Assignee: USV Pharmaceutical CorporationInventor: Martin L. Kantor
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Patent number: 4564677Abstract: Disclosed is a method of preparing N-amino compounds from corresponding secondary amines by reacting a secondary amine with nitrous acid and zinc in a neutral pH reaction media to form the corresponding N-amine.Type: GrantFiled: January 19, 1984Date of Patent: January 14, 1986Assignee: USV Pharmaceutical Corp.Inventor: Martin L. Kantor
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Patent number: 4258059Abstract: Compounds of the formula ##STR1## wherein: Ar and Ar' are independently alicyclic aryl or heterocyclic aryl groups;R.sub.1 is a substituent replacing a hydrogen on the ring and is independently hydroxy, alkyl, alkoxy, halogen, nitro, amino, monoalkyl-amino, dialkyl-amino, sulfhydryl, alkylmercapto, sulfonamido, carboxy, carbalkoxy, or trihalomethyl;n is an integer from 0 to 5 inclusive;R.sub.2 and R.sub.3 are independently hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, phenyl, or cycloalkyl-alkyl; andR.sub.4 and R.sub.5 are independently halogen or trihalomethyl, with the proviso that when both Ar and Ar' are phenyl and n is 0, both R.sub.2 and R.sub.3 are not hydrogen.Type: GrantFiled: June 21, 1979Date of Patent: March 24, 1981Assignee: USV Pharmaceutical CorporationInventors: Joseph Auerbach, Martin L. Kantor