Abstract: In one embodiment, the present invention discloses a process to directly prepare an unequal ratio of rotamers of an acid salt from a basic compound, by creative choice of a solvent medium. The process is particularly useful in preparing specific rotamers of pharmaceutically useful salts in desired preponderance.

Abstract: In one embodiment, the present invention discloses a process to directly prepare an unequal ratio of rotamers of an acid salt from a basic compound, by creative choice of a solvent medium. The process is particularly useful in preparing specific rotamers of pharmaceutically useful salts in desired preponderance.

Abstract: In one embodiment, the present invention discloses a process to directly prepare an unequal ratio of rotamers of an acid salt from a basic compound, by creative choice of a solvent medium. The process is particularly useful in preparing specific rotamers of pharmaceutically useful salts in desired preponderance.

Abstract: 3,4-Dihydro-10-[2-(dialkylamino)ethyl]-1-phenyl-1H-thiazino[4,3-a]indol-4-o l compounds having in free base form the formula ##STR1## where R.sub.1 and R.sub.2 are lower alkyl groups. The compounds of this invention exhibit anti-allergy properties and are indicated in the management of allergy.

Abstract: 3-[2-(Dialkylamino)ethyl]-2-(benzyl)indoles having in free base form the formula ##STR1## where R.sub.1 and R.sub.2 are lower alkyl groups and R.sub.3 is a phenyl, carboalkoxymethyl, lower alkyl or hydroxyethyl group. The compounds of the invention exhibit anti-aggression and anti-secretory properties and are indicated in the management of aggression and gastric hypersecretion.

Abstract: Pyrrolo[1,2-a]indole compounds having in free base form the formulas ##STR1## where R.sub.1, R.sub.2 and R.sub.3 are lower alkyl; R.sub.4 is lower alkyl, phenyl, lower alkoxy or ##STR2## in which R.sub.8 and R.sub.9 are hydrogen, lower alkyl, phenyl or benzyl; R.sub.5 is hydrogen or lower alkyl; A is O or NH; and R.sub.6 and R.sub.7 are lower alkyl, phenyl, or carbo(lower)alkoxy.

Abstract: The present invention concerns compounds of Formula I ##SPC1##wherein R.sub.1 is hydrogen, lower alkyl, aralkyl; R.sub.2 is hydrogen, lower alkyl, lower alkoxy, halogen, trifluoromethyl, cyano, nitro, and the like; R.sub.3 is lower alkyl; ##EQU1## (where R.sub.4 and R.sub.5 are lower alkyl), ##EQU2## (where R.sub.6 is hydrogen, lower alkyl, aryl, acetamido and R.sub.7 is lower alkyl), ##SPC2##(where R.sub.8 and R.sub.9 are hydrogen or lower alkyl), --CH(SO.sub.2 C.sub.6 H.sub.5).sub.2, ##SPC3## ##EQU3## (where R.sub.10 is hydrogen, CN, acyl), ##EQU4## (where R.sub.11 and R.sub.12 are lower alkyl), --SO.sub.2 C.sub.6 H.sub.5, --CONH.sub.2, --CO.sub.2 R.sub.13 (where R.sub.13 is lower alkyl), ##EQU5## (R.sub.14 and R.sub.15 are lower alkyl). These compounds are useful as sedatives and antiaggression agents.

Abstract: 3-Thiomethyl-2[2-(dialkylamino)ethyl]indoles having the following structural formula are disclosed ##SPC1##In the above formula, R.sub.1, R.sub.2, and R.sub.3 are hydrogen or alkyl, R.sub.4 is alkyl, aryl, aralkyl, or a heterocyclic, R.sub.5 is hydrogen, alkyl, halogen, alkoxy, hydroxyl and the like.These compounds exhibit central nervous system depressing properties and are useful as anti-aggression agents.

Abstract: Compounds having the following structural formula are disclosed: ##STR1## wherein R.sub.1 is hydrogen or methyl and R.sub.2, and R.sub.3 are hydrogen or alkyl. These compounds are useful as anti-inflammatory agents, antipyretics, analgesics.