Patents by Inventor Martin S. Angst

Martin S. Angst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230296622
    Abstract: Multiparametric analysis is performed at the single cell level of biological samples obtained from an individual during pregnancy to obtain a determination of changes in the interactome, integrating metabolome, immunome and proteome features during pregnancy that are predictive of time to onset of labor.
    Type: Application
    Filed: August 17, 2021
    Publication date: September 21, 2023
    Inventors: Brice L. Gaudilliere, Ina Stelzer, Xiaoyuan Han, Nima Aghaeepour, Martin S. Angst, Sajjad Ghaemi, Julien Hedou
  • Publication number: 20220011319
    Abstract: Multiparametric analysis is performed at the single cell level of biological samples obtained from an individual during pregnancy to obtain a determination of changes in immune cell subsets, which changes include, without limitation, altered activation states of proteins involved in signaling pathways. Changes occur in signaling pathways of these immune cells that are predictive of propensity to develop preeclampsia in the pregnancy.
    Type: Application
    Filed: November 14, 2019
    Publication date: January 13, 2022
    Inventors: Brice L. Gauilliere, Martin S. Angst, Nima Aghaeepour, David K. Stevenson, Xiaoyuan Han, Mohammad S. Ghaemi
  • Publication number: 20200352994
    Abstract: Methods and compositions are provided for treating a subject for aging-associated conditions, e.g., cognitive impairment conditions. Aspects of the methods include administering a young plasma-comprising blood product to an individual in need thereof, e.g., an individual suffering from or at risk of developing the aging-associated condition, e.g., aging-associated cognitive impairment. Also provided are compositions and kits thereof that find use in practicing methods of the invention.
    Type: Application
    Filed: May 21, 2020
    Publication date: November 12, 2020
    Inventors: Anton Wyss-Coray, Saul A. Villeda, Joseph M. Castellano, Jinte Middeldorp, Martin S. Angst, Jian Luo
  • Patent number: 10688130
    Abstract: Methods and compositions are provided for treating a subject for aging-associated conditions, e.g., cognitive impairment conditions. Aspects of the methods include administering a young plasma-comprising blood product to an individual in need thereof, e.g., an individual suffering from or at risk of developing the aging-associated condition, e.g., aging-associated cognitive impairment. Also provided are compositions and kits thereof that find use in practicing methods of the invention.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: June 23, 2020
    Assignees: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Anton Wyss-Coray, Saul A. Villeda, Joseph M. Castellano, Jinte Middeldorp, Martin S. Angst, Jian Luo
  • Patent number: 9238053
    Abstract: The invention provides for methods and compositions for treatment of pain via craniofacial mucosal administration of an analgesic compound (e.g. a non-opioid analgesic peptide, an NOP agonist or N/OFQ). Intranasal administration of certain analgesic peptides such as N/OFQ results in global analgesic effects.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: January 19, 2016
    Assignee: Nocicepta LLC
    Inventors: Lawrence R. Toll, David C. Yeomans, Martin S. Angst, Daniel I. Jacobs
  • Publication number: 20150241445
    Abstract: Multiparametric analysis at the single cell level of biological samples obtained from an individual undergoing surgery is used to obtain a determination of changes in immune cell subsets, which changes include, without limitation, altered activation states of proteins involved in signaling pathways. Changes occur in signaling pathways of these immune cells that are predictive of the recovery status of the individual.
    Type: Application
    Filed: February 23, 2015
    Publication date: August 27, 2015
    Inventors: Brice L. Gaudilliere, Gabriela K. Fragiadakis, Martin S. Angst, Garry P. Nolan
  • Publication number: 20150157664
    Abstract: Methods and compositions are provided for treating a subject for aging-associated conditions, e.g., cognitive impairment conditions. Aspects of the methods include administering a young plasma-comprising blood product to an individual in need thereof, e.g., an individual suffering from or at risk of developing the aging-associated condition, e.g., aging-associated cognitive impairment. Also provided are compositions and kits thereof that find use in practicing methods of the invention.
    Type: Application
    Filed: December 5, 2014
    Publication date: June 11, 2015
    Inventors: Anton Wyss-Coray, Saul A. Villeda, Joseph M. Castellano, Jinte Middeldorp, Martin S. Angst, Jian Luo
  • Patent number: 8551949
    Abstract: The invention provides for methods and compositions for treatment of pain via craniofacial mucosal administration of an analgesic compound (e.g. a non-opioid analgesic peptide, an NOP agonist or N/OFQ). Intranasal administration of certain analgesic peptides such as N/OFQ results in global analgesic effects.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: October 8, 2013
    Assignee: Nocicepta LLC
    Inventors: Lawrence R. Toll, David C. Yeomans, Martin S. Angst, Daniel I. Jacobs
  • Patent number: 8501691
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: August 6, 2013
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research & Education
    Inventors: David C. Yeomans, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs
  • Publication number: 20120322736
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Application
    Filed: May 24, 2012
    Publication date: December 20, 2012
    Inventors: David C. Yeomans, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs
  • Patent number: 8258096
    Abstract: The present invention relates to methods for the treatment or prevention of trigeminal nerve-associated pain, in particular chronic, acute and procedural-related pain. The methods comprise administration of analgesic agents to the trigeminal nerve system which results in analgesia to the facial or head region.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: September 4, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research Foundation
    Inventors: David C. Yeomans, William H. Frey, II, Daniel I. Jacobs, Martin S. Angst
  • Patent number: 8252745
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: August 28, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research Foundation
    Inventors: David C. Yeomans, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs
  • Patent number: 8202838
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: June 19, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research Foundation
    Inventors: David C. Yeomans, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs
  • Patent number: 8198240
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: June 12, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research Foundation
    Inventors: David C. Yeomans, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs
  • Publication number: 20120028898
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Application
    Filed: October 7, 2011
    Publication date: February 2, 2012
    Inventors: David C. YEOMANS, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs
  • Publication number: 20110021426
    Abstract: The invention provides for methods and compositions for treatment of pain via craniofacial mucosal administration of an analgesic compound (e.g. a non-opioid analgesic peptide, an NOP agonist or N/OFQ). Intranasal administration of certain analgesic peptides such as N/OFQ results in global analgesic effects.
    Type: Application
    Filed: July 27, 2010
    Publication date: January 27, 2011
    Inventors: Lawrence R. TOLL, David C. YEOMANS, Martin S. ANGST, Daniel I. JACOBS
  • Publication number: 20090291900
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Application
    Filed: March 23, 2009
    Publication date: November 26, 2009
    Inventors: David C. YEOMANS, Martin S. ANGST, William H. FREY, II, Daniel I. JACOBS
  • Publication number: 20090181880
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Application
    Filed: September 15, 2008
    Publication date: July 16, 2009
    Inventors: David C. YEOMANS, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs