Patents by Inventor Martin Sumner-Smith

Martin Sumner-Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucagon-like peptide-2 analogs
    Patent number: 5789379
    Abstract: Analogs of glucagon-like peptide 2, a product of glucagon gene expression, have been identified as intestinal tissue growth factors. Their formulation as pharmaceutical, and therapeutic use in treating disorders of the small bowel, are described.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: August 4, 1998
    Assignees: Allelix Biopharmaceutical Inc., 1149336 Ontario Inc.
    Inventors: Daniel J. Drucker, Anna E. Crivici, Martin Sumner-Smith
  • Anti-viral compositions
    Patent number: 5674849
    Abstract: An anti-viral composition includes a synergistic combination of an anti-viral nucleoside analogue, which may inhibit a virus-specific enzyme, such as viral thymidine kinase and reverse transcriptase, an anti-viral oligonucleotide compound having from 6 to 12 amino acid residues substantially all of which are D-arginine residues, and a pharmaceutically acceptable carrier. A method for treating a viral infection is also described.
    Type: Grant
    Filed: January 9, 1995
    Date of Patent: October 7, 1997
    Assignee: Allelix Biopharmaceuticals Inc.
    Inventors: Michael Twist, Martin Sumner-Smith
  • Peptide-based inhibitors of HIV replication
    Patent number: 5646120
    Abstract: Described herein are oligopeptides useful to inhibit replication in virally infected individuals. In a preferred embodiment of the invention, the oligopeptide is a D-arginine nonamer having N- and C-terminal protecting groups, which, at a 5 uM concentration, exhibits greater than 95% inhibition of HIV replication, in a standard assay.
    Type: Grant
    Filed: December 14, 1994
    Date of Patent: July 8, 1997
    Assignee: Allelix Biopharmaceuticals, Inc.
    Inventors: Martin Sumner-Smith, Richard W. Barnett, Lorne S. Reid, Nahum Sonenberg
  • Treatment of cytomegalovirus infection
    Patent number: 5633230
    Abstract: Described herein are anti-cytomegalovirus peptides. In a preferred embodiment, the peptide is acetyl-[D-Arg].sub.9 -NH.sub.2. The use of these peptides, either per se or in combination with other anti-CMV compounds, is disclosed as an effective method for controlling CMV infection.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: May 27, 1997
    Assignee: Allelix Biopharmaceuticals, Inc.
    Inventors: Michael Twist, deceased, Martin Sumner-Smith