Abstract: A method comprises the step of determining a minimum length of a lesion based on an imaging modality used to capture an image of the lesion and a slice thickness of the image, generating an extent cursor corresponding to the minimum size of the lesion, the extent cursor having a circular shape with a diameter corresponding to the minimum length and displaying the image of the lesion with the extent cursor positioned thereover.

Abstract: An apparatus comprises: a database (30) storing medical data including image medical data and non-image medical data for a plurality of patients; a digital processor (40) configured to (i) generate a features vector (56) comprising features indicative of a patient derived from patient medical data stored in the database including both patient image medical data and patient non-image medical data and (ii) perform multivariate analysis (64) on a features vector generated for a patient of interest to determine a proposed diagnosis for the patient of interest; and a user interface (42) configured to output a human perceptible representation of the proposed diagnosis for the patient of interest.

Abstract: This invention relates to a method and a correction system for correcting tracer-uptake measurements for patient specific variations in the tracer-uptake. Input data are received about the patient and subsequently it is determining whether the received input data include tracer-impact data that impact the tracer-uptake measurements for the patient. In case the tracer-impact data are included in the input data a comparing is performed where the tracer-impact data are compared with pre-stored reference data that have associated thereto a correction indicator indicating an amount of deviation of the tracer-uptake measurement due to the tracer-uptake dependent data. The correction indicator of the pre-stored reference data that match with the tracer-impact data is then used to correct the tracer-uptake measurements for the patient.

Abstract: A method comprises the step of determining a minimum length of a lesion based on an imaging modality used to capture an image of the lesion and a slice thickness of the image, generating an extent cursor corresponding to the minimum size of the lesion, the extent cursor having a circular shape with a diameter corresponding to the minimum length and displaying the image of the lesion with the extent cursor positioned thereover.

Abstract: A therapy system includes a diagnostic image scanner (12) that acquires a diagnostic image of a target region to be treated. A planning processor (70) is configured to generate a patient specific adaptive radiation therapy plan based on patient specific biomarkers before and during therapy. A first set of patient specific biomarkers is determined then used for the determination of a first normal tissue complication probability (NTCP) model and a first tumor control probability (TCP) model. A radiation therapy device (40) administers a first dose of radiation to the target region with a protocol based on the first NTCP model and the first TCP model. A second set of patient specific biomarkers is determined. A relationship between the first set and second set of patient specific biomarkers is used to determine a second NTCP model and a second TCP model.

Abstract: A method for radiotherapy monitoring is provided. The method comprises calculation of treatment-guiding indices of side-effects based on processing image derived descriptors and measurement values of selected disease specific biomarkers and optionally questionnaire data. A computer program product is also provided.

Abstract: A method includes obtaining an image of a region of interest of a subject, wherein the image is generated with image data produced by an imaging system used to scan the subject, obtaining a signal indicative of a physiological state of the subject before the scan, and displaying both the image and data indicative of the physiological state. In another aspect, a method includes correcting, via a processor, a tracer uptake value for a target region of interest based on a tracer uptake correction factor.

Abstract: A method allowing display of time-varying merged high resolution and low resolution image data with a smooth frame rate. In one embodiment the high resolution data is structural image data and the low resolution image data is functional image data. The functional image data is gathered (20) into groups and each group is rendered and merged (24) together. The merged images produced are then stored (28) in a First In First Out (FIFO) buffer for display. While the merged images are displayed the next set of functional image data is merged and rendered and supplied to the FIFO buffer, allowing a smooth frame rate to be achieved. A computer program and a medical imaging apparatus using the method are also disclosed.

Abstract: This invention relates to a method and a correction system for correcting tracer-uptake measurements for patient specific variations in the tracer-uptake. Input data are received about the patient and subsequently it is determining whether the received input data include tracer-impact data that impact the tracer-uptake measurements for the patient. In case the tracer-impact data are included in the input data a comparing is performed where the tracer-impact data are compared with pre-stored reference data that have associated thereto a correction indicator indicating an amount of deviation of the tracer-uptake measurement due to the tracer-uptake dependent data. The correction indicator of the pre-stored reference data that match with the tracer-impact data is then used to correct the tracer-uptake measurements for the patient.

Abstract: An apparatus comprises: a database (30) storing medical data including image medical data and non-image medical data for a plurality of patients; a digital processor (40) configured to (i) generate a features vector (56) comprising features indicative of a patient derived from patient medical data stored in the database including both patient image medical data and patient non-image medical data and (ii) perform multivariate analysis (64) on a features vector generated for a patient of interest to determine a proposed diagnosis for the patient of interest; and a user interface (42) configured to output a human perceptible representation of the proposed diagnosis for the patient of interest.

Abstract: This invention relates to a method and a system of evaluating toxicity level of a patient undergoing a cancer treatment protocol. Patient's related data including biomarkers of toxicity level caused by said cancer treatment are received. These biomarkers of toxicity level are then compared with a range of reference biomarkers of toxicity level caused during a similar cancer treatment. Finally, an alert signal is issued in case the biomarkers of toxicity level fall outside said range of reference biomarkers of toxicity level.

Abstract: A method for radiotherapy monitoring is provided. The method comprises calculation of treatment-guiding indices of side-effects based on processing image derived descriptors and measurement values of selected disease specific biomarkers and optionally questionnaire data. A computer program product is also provided.

Abstract: A therapy system includes a diagnostic image scanner (12) that acquires a diagnostic image of a target region to be treated. A planning processor (70) is configured to generate a patient specific adaptive radiation therapy plan based on patient specific biomarkers before and during therapy. A first set of patient specific biomarkers is determined then used for the determination of a first normal tissue complication probability (NTCP) model and a first tumor control probability (TCP) model. A radiation therapy device (40) administers a first dose of radiation to the target region with a protocol based on the first NTCP model and the first TCP model. A second set of patient specific biomarkers is determined. A relationship between the first set and second set of patient specific biomarkers is used to determine a second NTCP model and a second TCP model.

Abstract: A method includes obtaining an image of a region of interest of a subject, wherein the image is generated with image data produced by an imaging system used to scan the subject, obtaining a signal indicative of a physiological state of the subject before the scan, and displaying both the image and data indicative of the physiological state. In another aspect, a method includes correcting, via a processor, a tracer uptake value for a target region of interest based on a tracer uptake correction factor.

Abstract: The invention relates to a system and a method for the investigation of a body volume (3), particularly for the diagnosis of breast cancer According to the method, a sequence of X-ray projections (P, P?) from different directions is produced by a rotatable X-ray source (1) and a stationary digital X-ray detector (5). From these projections (P, P?), a set of sectional images (a, b, c, d) is calculated by tomosynthesis. A physician may indicate a suspicious structure on a reference image (R) that is derived from one of the projections (P, P?) or sectional images (a, b, c, d) and displayed on a monitor (6). The computer (7) may then locate the structure on all sectional images (a, b, c, d) and calculate the similarity of a corresponding image feature. The sectional 10 image at which the similarity is strongest then indicates the depth (zo) at which the structure (4) is positioned in the body volume (3).

Abstract: A method allowing display of time-varying merged high resolution and low resolution image data with a smooth frame rate. In one embodiment the high resolution data is structural image data and the low resolution image data is functional image data. The functional image data is gathered (20) into groups and each group is rendered and merged (24) together. The merged images produced are then stored (28) in a First In First Out (FIFO) buffer for display. While the merged images are displayed the next set of functional image data is merged and rendered and supplied to the FIFO buffer, allowing a smooth frame rate to be achieved. A computer program and a medical imaging apparatus using the method are also disclosed.

Abstract: The invention relates to a system and a method for the investigation of a body volume (3), particularly for the diagnosis of breast cancer According to the method, a sequence of X-ray projections (P, P?) from different directions is produced by a rotatable X-ray source (1) and a stationary digital X-ray detector (5). From these projections (P, P?), a set of sectional images (a, b, c, d) is calculated by tomosynthesis. A physician may indicate a suspicious structure on a reference image (R) that is derived from one of the projections (P, P?) or sectional images (a, b, c, d) and displayed on a monitor (6). The computer (7) may then locate the structure on all sectional images (a, b, c, d) and calculate the similarity of a corresponding image feature. The sectional 10 image at which the similarity is strongest then indicates the depth (z0) at which the structure (4) is positioned in the body volume (3).

Abstract: The invention relates to a display device for rendering gray tone images on a monitor (31) controlled by s electron rays, wherein a correction unit (33) is provided for generating s output image signals As, which comprise gray tone values forming part of a set K of correction gray tones, from an image signal (34) which comprises gray tone values forming part of a set M of original gray tones (23), and the s output image signals As, after a D/A conversion, are fed each to one electron ray for a brightness-corrected rendering of a gray tone in one pixel of the monitor (31) for the purpose of adapting the brightness distribution of the monitor to the optimum perceptional brightness distribution.

Abstract: In a method and arrangement for correcting an arrangement for driving imagereproducing means subject to inertia, and particularly liquid crystal displays, wherein a stored correcting variable is added to infed video signals to compensate for the effects of inertia, which correcting variable depends on changes in the video signals from frame to frame, and wherein the corrected video signals are conveyed to the image-reproducing means, provision is made for a test pattern that contains signal jumps that occur from frame to frame to be generated, for the signal jumps to vary in respect of their sign, their size and their position in the amplitude range of the video signals, for the test video signals to be shown on the imagereproducing means at least in a part that is covered by at least one opto-electrical sensor, and for correcting parameters to be derived from the signals generated by the at least one optoelectrical sensor while taking account of the totality of the signals generated by the at least one opto-

Abstract: In a system for driving inertia-prone picture-reproducing devices, in particular liquid-crystal displays, in which a correcting value that depends on changes in the video signals from frame to frame is added to incoming video signals to compensate for the inertial effects and in which the corrected video signals are passed to the picture-reproducing device to form the correcting value, a model of the picture-reproducing device is provided that has a state variable as an output variable, the video signals as a first input variable and the state variable from a preceding frame as a second input variable. Furthermore, to derive the correcting value, a function having the incoming video signals and the state variable of the preceding variable as input variables and the corrected video signals as an output variable.