Patents by Inventor Martyn Alun Sharpe

Martyn Alun Sharpe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method And Apparatus For Oncomagnetic Treatment
    Publication number: 20230271024
    Abstract: To disrupt mitochondrial function in certain cells, controlling hardware causes a magnet to oscillate so as to generate an oscillating magnetic field. The oscillating magnetic field is applied to a volume of tissue including cells with degraded mitochondria to trigger apoptosis in the cells with degraded mitochondria.
    Type: Application
    Filed: February 7, 2023
    Publication date: August 31, 2023
    Inventors: Santosh Anand Helekar, David Stuart Baskin, Martyn Alun Sharpe, Kumar Pichumani
  • Method and apparatus for oncomagnetic treatment
    Patent number: 11571585
    Abstract: The disclosure provides methods of cancer treatment and apparatus and, more particularly, to non-invasive cancer treatments utilizing oscillating magnetic fields to disrupt mitochondrial function or induce apoptosis or another mechanism of cell death in cancer cells. The disclosure also provides a device for providing an OMF treatment to a subject.
    Type: Grant
    Filed: December 31, 2021
    Date of Patent: February 7, 2023
    Assignee: THE METHODIST HOSPITAL
    Inventors: Santosh Anand Helekar, David Stuart Baskin, Martyn Alun Sharpe, Kumar Pichumani
  • METHOD AND APPARATUS FOR ONCOMAGNETIC TREATMENT
    Publication number: 20220193436
    Abstract: The disclosure provides methods of cancer treatment and apparatus and, more particularly, to non-invasive cancer treatments utilizing oscillating magnetic fields to disrupt mitochondrial function or induce apoptosis or another mechanism of cell death in cancer cells. The disclosure also provides a device for providing an OMF treatment to a subject.
    Type: Application
    Filed: December 31, 2021
    Publication date: June 23, 2022
    Inventors: Santosh Anand Helekar, David Stuart Baskin, Martyn Alun Sharpe, Kumar Pichumani
  • METHOD AND APPARATUS FOR ONCOMAGNETIC TREATMENT
    Publication number: 20210402199
    Abstract: To disrupt mitochondrial function in certain cells, controlling hardware causes a magnet to oscillate so as to generate an oscillating magnetic field. The oscillating magnetic field is applied to a volume of tissue including cells with degraded mitochondria to trigger apoptosis in the cells with degraded mitochondria.
    Type: Application
    Filed: November 13, 2019
    Publication date: December 30, 2021
    Inventors: Santosh Anand Helekar, David Stuart Baskin, Martyn Alun Sharpe, Kumar Pichumani
  • Chemotherapeutic compositions and methods for treating human gliomas
    Patent number: 10555936
    Abstract: Disclosed are compound for targeting chemotherapeutic agents to mammalian mitochondria. Also disclosed are monoamine oxidase-specific compositions, and methods of using them for the selective therapy of mammalian cancers, and in particular, in the treatment of human gliomas. Also disclosed are methods employing the novel targeted chemotherapeutics with one or more conventional anti-cancer therapies, including, for example, radiotherapy, or multi-drug regimens.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: February 11, 2020
    Assignee: THE METHODIST HOSPITAL
    Inventors: David S. Baskin, Martyn Alun Sharpe
  • Chemotherapeutic Compositions and Methods for Treating Human Gliomas
    Publication number: 20140323513
    Abstract: Disclosed are compound for targeting chemotherapeutic agents to mammalian mitochondria. Also disclosed are monoamine oxidase-specific compositions, and methods of using them for the selective therapy of mammalian cancers, and in particular, in the treatment of human gliomas. Also disclosed are methods employing the novel targeted chemotherapeutics with one or more conventional anti-cancer therapies, including, for example, radiotherapy, or multi-drug regimens.
    Type: Application
    Filed: April 30, 2014
    Publication date: October 30, 2014
    Inventors: David S. Baskin, Martyn Alun Sharpe
  • Compositions and Methods for Quantitative Histology, Calibration of Images in Fluorescence Microscopy, and ddTUNEL Analyses
    Publication number: 20130157261
    Abstract: Disclosed are compositions and methods for quantitation and calibration of images in fluorescence microscopy. Also provided are tissue phantoms that contain known amount(s) of fluorophore standard(s), as well as components and diagnostic kits containing the same for use in various histological analyses. In certain embodiments, three distinct nucleic-acid based assays provide improvements over conventional TUNEL methods to facilitate precise quantitation of a variety of nucleic acids obtained from a biological sample.
    Type: Application
    Filed: June 1, 2012
    Publication date: June 20, 2013
    Applicant: The Methodist Hospital Research Institute
    Inventors: Martyn Alun Sharpe, David S. Baskin