Patents by Inventor Marvin R. Williams

Marvin R. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10866254
    Abstract: A system that rapidly detects the presence of a target analyte in a biological test sample, which includes a sensor for measuring a detectable signal generated upon the reaction of a biosensor reagent with a specific target analyte within the sample; a reservoir card that includes the biosensor reagent that further includes living, engineered biological cells, and wherein the reservoir card is configured to interface with a test cartridge base; a test cartridge base configured to accept the reservoir card and to be placed within the testing device, wherein the test cartridge base further includes a reaction chamber adapted to receive both the biosensor reagent and the sample and a fluid displacement mechanism that includes a dispensing plunger, wherein actuation of the dispensing plunger displaces the biosensor reagent in the reservoir into the reaction chamber where the biosensor reagent is mixed with the sample; and a function verification cartridge adapted to be received and recognized by the testing devic
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: December 15, 2020
    Assignee: Fundamental Solutions Corporation
    Inventors: Christopher T. Phelan, Stephan M. Lawson, Andrew Weiman, Marvin R. Williams, Charles McBrairty, Joel S. Lwande
  • Patent number: 10613083
    Abstract: A biosensor system for the detection of target analytes that includes a living biological cell of a predetermined type; a signal-generating reporter associated with the living biological cell; a signal transduction pathway or other activator mechanism or means associated with the signal-generating reporter; a universal detector element associated with the activator mechanism; and an analyte binding element associated with the universal detector element, wherein the analyte binding element is specific to both the universal detector element and a target analyte.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: April 7, 2020
    Assignee: Fundamental Solutions Corporation
    Inventors: Thomas J. Zupancic, Joseph D. Kittle, Lingchun Zeng, Srikanth Vedamoorthy, Richard S. Brody, Marvin R. Williams
  • Publication number: 20190317116
    Abstract: A system that rapidly detects the presence of a target analyte in a biological test sample, which includes a sensor for measuring a detectable signal generated upon the reaction of a biosensor reagent with a specific target analyte within the sample; a reservoir card that includes the biosensor reagent that further includes living, engineered biological cells, and wherein the reservoir card is configured to interface with a test cartridge base; a test cartridge base configured to accept the reservoir card and to be placed within the testing device, wherein the test cartridge base further includes a reaction chamber adapted to receive both the biosensor reagent and the sample and a fluid displacement mechanism that includes a dispensing plunger, wherein actuation of the dispensing plunger displaces the biosensor reagent in the reservoir into the reaction chamber where the biosensor reagent is mixed with the sample; and a function verification cartridge adapted to be received and recognized by the testing devic
    Type: Application
    Filed: April 16, 2018
    Publication date: October 17, 2019
    Inventors: Christopher T. PHELAN, Stephan M. LAWSON, Andrew WEIMAN, Marvin R. WILLIAMS, Charles MCBRAIRTY, Joel S. LWANDE
  • Publication number: 20190128913
    Abstract: A system for use in sample analysis that includes a biosensor reagent that includes living biological cells that are adapted to recognize an analyte of interest; a plurality of reservoir cards, wherein each reservoir card is adapted to store the biosensor reagent; and at least one dispensing unit for storing the reservoir cards and dispensing the reservoir cards one at a time, wherein the at least one dispensing unit further includes a housing that includes an internal chamber for containing a plurality of reservoir cards stacked on top of one another; a moveable platform positioned within the housing, wherein the platform is positioned beneath the stack of reservoir cards, and where in the platform is adapted to lift the stack of reservoir cards a predetermined distance after a reservoir card has been dispensed; and a shuttle positioned within the housing, wherein the shuttle is positioned on top of the stack of reservoir cards, and wherein the shuttle is adapted to dispense a single reservoir card from the
    Type: Application
    Filed: October 26, 2017
    Publication date: May 2, 2019
    Inventors: Christopher T. PHELAN, Stephan M. LAWSON, Andrew WEIMAN, Marvin R. WILLIAMS, Charles MCBRAIRTY, Joel S. LWANDE
  • Patent number: 10241054
    Abstract: A system for use in rapid sample analysis that includes a biosensor reagent, wherein the biosensor reagent includes living biological cells; a reservoir card, wherein the reservoir card stores the biosensor reagent; and a test cartridge base, wherein the test cartridge base is configured to accept the reservoir card, and wherein the test cartridge base further includes a contoured reaction chamber; and an inlet channel connected to and entering the reaction chamber at a predetermined angle thereto.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: March 26, 2019
    Assignee: Fundamental Solutions Corporation
    Inventors: Marvin R. Williams, Charles McBrairty, Daniel W. Pfautz, Thomas J. Zupancic, Lingchun Zeng, Andrew Weiman, Richard S. Brody, Joseph D. Kittle, Anthony Truscott, Robert Baranowski
  • Patent number: 10094783
    Abstract: A system for use in rapid sample analysis that includes a biosensor reagent, wherein the biosensor reagent includes living biological cells; a reservoir card, wherein the reservoir card stores the biosensor reagent; and a test cartridge base, wherein the test cartridge base is configured to accept the reservoir card, and wherein the test cartridge base further includes a reaction chamber having a central axis, wherein the reaction chamber has the shape of a revolved half ellipse; and an inlet channel connected to the reaction chamber, wherein the inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal, and wherein the inlet channel is offset from the central axis of the reaction chamber.
    Type: Grant
    Filed: July 20, 2016
    Date of Patent: October 9, 2018
    Assignee: Fundamental Solutions Corporation
    Inventors: Marvin R. Williams, Charles McBrairty, Daniel W. Pfautz, Thomas J. Zupancic, Lingchun Zeng, Andrew Weiman, Richard S. Brody, Joseph D. Kittle, Anthony Truscott, Robert Baranowski
  • Publication number: 20180180608
    Abstract: A biosensor system for the detection of target analytes that includes a living biological cell of a predetermined type; a signal-generating reporter associated with the living biological cell; a signal transduction pathway or other activator mechanism or means associated with the signal-generating reporter; a universal detector element associated with the activator mechanism; and an analyte binding element associated with the universal detector element, wherein the analyte binding element is specific to both the universal detector element and a target analyte.
    Type: Application
    Filed: December 20, 2017
    Publication date: June 28, 2018
    Inventors: Thomas J. ZUPANCIC, Joseph D. KITTLE, Lingchun ZENG, Srikanth VEDAMOORTHY, Richard S. BRODY, Marvin R. WILLIAMS
  • Publication number: 20180066300
    Abstract: A method for enhancing the performance of a reaction chamber for use in a sample analysis system that includes providing a reaction chamber, wherein the reaction chamber has a predetermined geometry, wherein the reaction chamber has light collecting properties, and wherein the reaction chamber has an inner surface; and modifying the inner surface of the reaction chamber to include a predetermined degree of reflectivity, wherein the predetermined degree of reflectivity enhances the light collecting properties of the reaction chamber.
    Type: Application
    Filed: October 23, 2017
    Publication date: March 8, 2018
    Inventors: Marvin R. WILLIAMS, Charles MCBRAIRTY, Andrew WEIMAN, Daniel W. PFAUTZ, Thomas J. ZUPANCIC
  • Patent number: 9701994
    Abstract: A system for use in rapid sample analysis that includes a biosensor reagent, wherein the biosensor reagent includes living biological cells; a reservoir card, wherein the reservoir card stores the biosensor reagent; and a test cartridge base, wherein the test cartridge base is configured to accept the reservoir card, and wherein the test cartridge base further includes a reaction chamber having a central axis, wherein the reaction chamber has the shape of a revolved half ellipse; and an inlet channel connected to the reaction chamber, wherein the inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal, and wherein the inlet channel is offset from the central axis of the reaction chamber.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: July 11, 2017
    Assignee: Fundamental Solutions Corporation
    Inventors: Marvin R. Williams, Charles McBrairty, Daniel W. Pfautz, Thomas J. Zupancic, Lingchun Zeng, Andrew Weiman, Richard S. Brody, Joseph D. Kittle, Anthony Truscott, Robert Baranowski
  • Patent number: 9701995
    Abstract: A test cartridge for use in sample analysis is provided. The test cartridge includes a reservoir card that further includes a reagent that includes living biological cells; and a test cartridge base configured to accept the reservoir card. The reservoir card is configured to interface with a test cartridge base through at least one fluid port. The test cartridge base includes an elliptical reaction chamber having a central axis and an inlet channel connected to the reaction chamber. The inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal and is offset from the central axis of the reaction chamber. Upon introducing a sample to be analyzed into the test cartridge base through the inlet channel, the sample is homogeneously mixed with the reagent while minimizing damage to the living biological cells.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: July 11, 2017
    Assignee: Fundamental Solutions Corporation
    Inventors: Marvin R. Williams, Charles McBrairty, Daniel W. Pfautz, Thomas J. Zupancic, Lingchun Zeng, Andrew Weiman, Richard S. Brody, Joseph D. Kittle, Anthony Truscott, Robert Baranowski
  • Publication number: 20160327487
    Abstract: A system for use in rapid sample analysis that includes a biosensor reagent, wherein the biosensor reagent includes living biological cells; a reservoir card, wherein the reservoir card stores the biosensor reagent; and a test cartridge base, wherein the test cartridge base is configured to accept the reservoir card, and wherein the test cartridge base further includes a contoured reaction chamber; and an inlet channel connected to and entering the reaction chamber at a predetermined angle thereto.
    Type: Application
    Filed: July 19, 2016
    Publication date: November 10, 2016
    Inventors: Marvin R. WILLIAMS, Charles McBRAIRTY, Daniel W. PFAUTZ, Thomas J. ZUPANCIC, Lingchun ZENG, Andrew WEIMAN, Richard S. BRODY, Joseph D. KITTLE, Anthony TRUSCOTT, Robert BARANOWSKI
  • Publication number: 20160327488
    Abstract: A system for use in rapid sample analysis that includes a biosensor reagent, wherein the biosensor reagent includes living biological cells; a reservoir card, wherein the reservoir card stores the biosensor reagent; and a test cartridge base, wherein the test cartridge base is configured to accept the reservoir card, and wherein the test cartridge base further includes a reaction chamber having a central axis, wherein the reaction chamber has the shape of a revolved half ellipse; and an inlet channel connected to the reaction chamber, wherein the inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal, and wherein the inlet channel is offset from the central axis of the reaction chamber.
    Type: Application
    Filed: July 20, 2016
    Publication date: November 10, 2016
    Inventors: Marvin R. WILLIAMS, Charles McBRAIRTY, Daniel W. PFAUTZ, Thomas J. ZUPANCIC, Lingchun ZENG, Andrew WEIMAN, Richard S. BRODY, Joseph D. KITTLE, Anthony TRUSCOTT, Robert BARANOWSKI
  • Publication number: 20150198594
    Abstract: A test cartridge for use in sample analysis is provided. The test cartridge includes a reservoir card that further includes a reagent that includes living biological cells; and a test cartridge base configured to accept the reservoir card. The reservoir card is configured to interface with a test cartridge base through at least one fluid port. The test cartridge base includes an elliptical reaction chamber having a central axis and an inlet channel connected to the reaction chamber. The inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal and is offset from the central axis of the reaction chamber. Upon introducing a sample to be analyzed into the test cartridge base through the inlet channel, the sample is homogeneously mixed with the reagent while minimizing damage to the living biological cells.
    Type: Application
    Filed: March 26, 2015
    Publication date: July 16, 2015
    Inventors: Marvin R. WILLIAMS, Charles MCBRAIRTY, Daniel W. PFAUTZ, Thomas J. ZUPANCIC, Lingchun ZENG, Andrew WEIMAN, Richard S. BRODY, Joseph D. KITTLE, Anthony TRUSCOTT, Robert BARANOWSKI
  • Publication number: 20150197784
    Abstract: A system for use in rapid sample analysis that includes a biosensor reagent, wherein the biosensor reagent includes living biological cells; a reservoir card, wherein the reservoir card stores the biosensor reagent; and a test cartridge base, wherein the test cartridge base is configured to accept the reservoir card, and wherein the test cartridge base further includes a reaction chamber having a central axis, wherein the reaction chamber has the shape of a revolved half ellipse; and an inlet channel connected to the reaction chamber, wherein the inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal, and wherein the inlet channel is offset from the central axis of the reaction chamber.
    Type: Application
    Filed: March 26, 2015
    Publication date: July 16, 2015
    Inventors: Marvin R. WILLIAMS, Charles MCBRAIRTY, Daniel W. PFAUTZ, Thomas J. ZUPANCIC, Lingchun ZENG, Andrew WEIMAN, Richard S. BRODY, Joseph D. KITTLE, Anthony TRUSCOTT, Robert BARANOWSKI
  • Patent number: 9023640
    Abstract: A portable system for real time detection of the presence of an infectious agent in a biological sample employs a reagent which detects the presence of a specific infectious agent in the sample, and emits a detectable signal when the reagent reacts with the sample and detects the presence of the infectious agent. A test cartridge has a reaction chamber for receiving the sample and the reagent. The reaction chamber has a predetermined internal geometry and at least one inner surface. Introducing the sample and the reagent into the test cartridge mixes the sample and the reagent. A testing unit receives the test cartridge, and includes a sensor for detecting an emitted detectable signal. The detection of the emitted detectable signal is indicative of the presence of the infectious agent in the sample.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: May 5, 2015
    Assignee: Fundamental Solutions Corporation
    Inventors: Marvin R. Williams, Charles McBrairty, Daniel W. Pfautz, Thomas J. Zupancic, Lingchun Zeng, Andrew Weiman, Richard S. Brody, Joseph Kittle, Anthony Truscott, Robert Baranowski
  • Patent number: 4089662
    Abstract: An oil treatment system for reclaiming used oil including apparatus for feeding the oil first through a filter for removing solid contaminants therefrom then through a vaporizer unit wherein it is heated under a vacuum while in a flowing film form to remove water, dissolved gases and volatile contaminants therefrom, and automatic control devices whereby treated oil cannot be discharged until it has been subjected to heat and vacuum in the necessary degrees, and whereby the system, once initiated by a starting or stopping signal, is automated to initiate or terminate operation of the various components of the system in a sequence operable to produce efficient, trouble-free operation of the system as a whole.
    Type: Grant
    Filed: June 22, 1977
    Date of Patent: May 16, 1978
    Assignee: Allen Filters, Inc.
    Inventor: Marvin R. Williams
  • Patent number: D806890
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: January 2, 2018
    Assignee: Fundamental Solutions Corporation
    Inventors: Marvin R. Williams, Charles McBrairty, Daniel W. Pfautz, Andrew Weiman
  • Patent number: D807213
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: January 9, 2018
    Assignee: Fundamental Solutions Corporation
    Inventors: Marvin R. Williams, Charles McBrairty, Daniel W. Pfautz, Andrew Weiman, Edward Mitchell
  • Patent number: D846145
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: April 16, 2019
    Assignee: Fundamental Solutions Corporation
    Inventors: Marvin R. Williams, Charles McBrairty, Daniel W. Pfautz, Andrew Weiman