Patents by Inventor Mary Ann Zink

Mary Ann Zink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric viral packaging signal without gag gene sequences
    Patent number: 6573091
    Abstract: A chimeric viral packaging signal is described for the transmission of genetic materials via retrovirus. The packaging signal contains an essential packaging nucleic acid sequence and a non-essential nucleic acid sequence. The packaging signal lacks gag gene sequences, and has approximately one order of magnitude greater infectivity than retrovirus-derived packaging signals without gag gene sequences. The packaging signal of the invention can be used to transmit genetic material for gene therapy, cell therapy, or other biotechnological applications.
    Type: Grant
    Filed: September 18, 2000
    Date of Patent: June 3, 2003
    Assignee: Nature Technology Corporation
    Inventors: Clague Hodgson, Mary Ann Zink, Guoping Xu
  • Self-assembling genes, vectors and uses thereof
    Patent number: 6410220
    Abstract: The invention relates to a method for directing the self-assembly of a gene or gene assembly having three and preferably six or more fragments in a directionally and spatially ordered fashion to produce a gene, gene vector or large nucleic acid molecule. The method can be used to create libraries, such as combinatorial libraries. In another embodiment of the invention a vector is described for the incorporation and screeming of endogenous mouse promoter elements for the identification of cell-specific promoters.
    Type: Grant
    Filed: August 26, 1999
    Date of Patent: June 25, 2002
    Assignee: Nature Technology Corp
    Inventors: Clague P. Hodgson, Mary Ann Zink, Guoping Xu