Abstract: A catheter and method of using the catheter for the delivery of therapeutic or diagnostic liquid within a body lumen of a patient. The catheter has an outer inflatable member which has a wall with a plurality of apertures which eject therapeutic or diagnostic liquid in a jet-like form deep within the lumenal tissue adjacent to the outer inflatable member. In one embodiment the catheter has an inner inflatable member disposed within the outer inflatable member which upon inflation expands the outer tubular member so as to dilatate a stenotic region of a body lumen such as an artery. The inflatable member may be provided with proximal and distal ends which expand to larger diameters than the central inflatable section so as to seal the larger ends and prevent the loss of fluid.

Abstract: Providing fluid to an internal delivery site of a patient includes moving the fluid from a fluid reservoir through a conduit and through a delivery device at the delivery site while maintaining the fluid at a predetermined pressure. The delivery device may comprise an inflatable balloon with apertures formed in its periphery for directing the fluid into the vessel walls. Pressurized fluid is provided through the apertures of the balloon to the vessel wall. The pressure is automatically controlled to avoid both pressure spikes and unacceptable deflation of the balloon during administration of the fluid. A further feature includes comparing the pressure with the volume infused and in the event that pressure decreases while the volume infused increases beyond certain limits, the delivery of the fluid is stopped. Further features include a timer for limiting the inflation time of the delivery device and a volume detector for controlling the amount of fluid delivered.