Patents by Inventor Mary Dyszlewski

Mary Dyszlewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MATRIX METALLOPROTEASE (MMP) TARGETED AGENTS FOR IMAGING AND THERAPY
    Publication number: 20140271465
    Abstract: The present invention provides compound conjugates of matrix metalloprotease inhibitors and linked metal chelators which are useful for imaging solid tumors and treating and diagnosing certain types of diseases such as cancer.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: Mallinckrodt LLC
    Inventors: John N. Freskos, Mary Dyszlewski, Lori Chinen, Hector Knight, Michelle Schmidt
  • Risk Stratification of Patients with Chronic Myocardial Infarction
    Publication number: 20090299177
    Abstract: The present invention is directed to novel radiopharmaceuticals, which can be used to image myocardium. In addition, the present invention is directed to methods for risk stratification of patients who have suffered at least one myocardial infarction.
    Type: Application
    Filed: June 2, 2009
    Publication date: December 3, 2009
    Applicant: Mallinckrodt Inc.
    Inventors: Raghoottama Pandurangi, Raghavan Rajagopalan, Mary Dyszlewski, Robert Carretta, Joseph Pierro
  • Formulation of Tc and Re carbonyl complexes using stannous ion as the reductant for pertechnetate and perrhenate
    Publication number: 20050276755
    Abstract: The invention relates to novel aminocarboxylate ligands that are suitable for complexing with a radionuclide, and are useful as therapeutic agents and as imaging agents for diagnostic purposes. In accordance with the present invention, a method of preparing a compound of formula fac-[M(CO)3(OH2)3]+??(I) where M is MN, 99mTc, 186Re or 188Re, involves reacting a metal in permetallate form with carbon monoxide and stannous ion. The compound of formula (I) can be reacted with a ligand Lx to form a compound of the formula fac-[M(CO)3Lx]n??(II) wherein M is as defined above, Lx is a monodentate or multidentate ligand or a mixture of these ligands, and n is a charge of the ligand Lx increased with one+charge. The invention also is directed to novel compounds, and kits for carrying out the disclosed methods.
    Type: Application
    Filed: August 17, 2005
    Publication date: December 15, 2005
    Applicant: Mallinckrodt, Inc.
    Inventors: David Pipes, Mary Dyszlewski, Elizabeth Webb