Abstract: A topical barrier composition contains a, synthetic, polymeric, hydrophobic silicone material, a bentonite component, zinc oxide, water and an unctuous carrier base for the other ingredients of the composition. The composition provides a barrier function protecting mammalian epidermis against external insults such as hyperhydration and maceration from any cause with an intended use for protection against extended periods of exposure to urine and feces.

Abstract: Decubitus ulcers are treated with a preconditioning aqueous medium and then with a non-systemic basic ointment. The aqueous medium comprises an aqueous solution of pyridoxine hydrochloride, zinc chloride, dextrose, ethanol and sodium chloride, with a trace of phenyl mercuric nitrate N.F., and has a pH in the range of 4.3 to 6.8 so as to facilitate ionization of naturally occurring amino acids at the wound site. The ointment comprises calcium carbonate, magnesium hydroxide, aluminum hydroxide, zinc chloride, sodium chloride, anhydrous lanolin, hydrophilic ointment and vitamin A and has a pH in the range of from about 6.5 to 9.0 so as to facilitate chelation of the amino acid and zinc ions and enhance tissue repair.

Abstract: A topical ointment composition is provided which includes a mixture of non-systemic bases comprising calcium carbonate, magnesium hydroxide, and aluminum hydroxide. The composition also includes an anhydrous lanolin base carrier material and a hydrophilic ointment base carrier material, and the ointment composition is effective to essentially adjust the acid-base balance at the area of topical application to a point which corresponds with normal healthy body tissue. The composition may further include a compound having pharmaceutically acceptable anesthetic properties. In addition to the topical ointment composition, a method is provided for treating skin injuries involving inflammation or destruction of tissue, such as decubitus ulcers, varicose ulcers and burns, which method involves preparing the above noted composition and applying it to the affected area.