Patents by Inventor Mary Starnes Saunders

Mary Starnes Saunders has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay preparation containing capture and detection polynucleotides covalently bound to substrates with a heterobifunctional crosslinking agent
    Patent number: 5663318
    Abstract: Heterofunctional crosslinking agents are used to produce a device for detecting a target polynucleotide. Synthetic single stranded capture and detector polynucleotides are covalently immobilized to plastic surfaces by novel heterofunctional reagents. The capture and detector polynucleotides are covalently attached through a synthetic region of amine-bearing nucleotides that interact with reactive moieties on the heterofunctional crosslinker. The regions of the capture and detector polynucleotides that can hybridize a diagnostically important target polynucleotide are protected from binding to a solid phase support by intrastrand pairing. This system provides monolayers of immobilized polynucleotides with precise orientation and unimpaired diagnostic coding regions.
    Type: Grant
    Filed: January 31, 1995
    Date of Patent: September 2, 1997
    Inventors: Randall Kevin Pegg, Mary Starnes Saunders