Abstract: A vehicle control device for controlling platooning of platoon participating vehicles by connecting the platoon participating vehicles to one another via radio communication, the platoon participating vehicles include a lead vehicle and follow-up vehicles that perform automatic follow-up running in line at a predetermined intervehicle distance from the lead vehicle, the device comprises a control portion that, during execution of the platooning, sets a permissible output range of a drive amount with a current gear ratio of an automatic transmission remaining kept, as a change characteristic of the drive amount in each of the platoon participating vehicles so that change of the drive amount in response to change of a drive demand amount lies within a predetermined range, the automatic transmission being included in each of the platoon participating vehicles to transmit power of a power source to driving wheels.

Abstract: The present invention establishes a molecular therapy for glycogen storage disease type Ia. The present invention provides an oligonucleotide of 15-30 bases comprising a nucleotide sequence complementary to die cDNA of G6PC gene with c.648G>T mutation, wherein the oligonucleotide comprises a sequence complementary to a region comprising any site between the 82nd to the 92nd nucleotide from the 5? end of exon 5 of the G6PC gene with c.648C>T mutation, a pharmacologically acceptable salt or solvate thereof. Also provided is a pharmaceutical drug comprising the oligonucleotide, a pharmacologically acceptable salt or solvate thereof (e.g., therapeutic drug for glycogen storage disease type Ia).

Abstract: A vehicle control apparatus includes: a follow-up-running control portion configured to execute a follow-up running control for causing a vehicle to run following a preceding vehicle with a target inter-vehicle distance; and a shift control portion configured to change a gear ratio of an automatic transmission in accordance with a predetermined shifting condition. The shift control portion is configured to set a high fluid-temperature determination value, based on information relating to the preceding vehicle that affects an air flow rate. When a fluid temperature of the automatic transmission is not lower than the high fluid-temperature determination value, the shift control portion is configured to change the shifting condition such that a higher-speed gear position making the gear ratio lower is more frequently established in the automatic transmission than when the fluid temperature of the automatic transmission is lower than the high fluid-temperature determination value.

Abstract: To output music other than original music, which is suitable to keep a player excited, in the place of a part of the original music, such as a beginning or ending thereof, which is unsuitable to serve as game music. When main part end timing TE arrives while outputting original music MO1, connection music MI2, correlated with original music MO2, which is next game music, begins playing.

Abstract: To output music other than original music, which is suitable to keep a player excited, in the place of a part of the original music, such as a beginning or ending thereof, which is unsuitable to serve as game music. When main part end timing TE arrives while outputting original music MO1, connection music MI2, correlated with original music MO2, which is next game music, begins playing.