Patents by Inventor Masahiko Iijima

Masahiko Iijima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9557264
    Abstract: To enable determination of if there is an influence of foreign-body reactions on the result of quantitative determination conducted with a scattered light measurement method. Proposed is an automatic analysis device including a light source configured to irradiate a reaction solution with light, a plurality of light receivers configured to receive scattered light generated from the reaction solution at different light-receiving angles, a first data processing unit configured to process reaction process data measured by one of the light receivers to quantitatively determine a concentration of a substance in the reaction solution, and a second data processing unit configured to determine if the quantitative determination of the concentration of the substance has been performed normally on the basis of a ratio of a plurality of computed values, the plurality of computed values having been calculated from a plurality of pieces of reaction process data measured by the respective light receivers.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: January 31, 2017
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Sakuichiro Adachi, Hajime Yamazaki, Masahiko Iijima
  • Patent number: 9506942
    Abstract: An automatic analyzer detects measurement value abnormalities stemming from reaction process anomalies caused by the presence of foreign matter or bubbles. It is determined whether the results of concentration calculation based on light quantity data from multiple target detectors each fall within an applicable determination range. If the results fall within the determination range, an average value of the results of concentration calculation with the target detectors is calculated, and if not, an out-of-determination-range flag is given. A default fluctuation range is retrieved regarding the average value of the results of concentration calculation. The fluctuation range of the results of concentration calculation with the multiple target detectors is calculated.
    Type: Grant
    Filed: November 22, 2012
    Date of Patent: November 29, 2016
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Akihisa Makino, Masahiko Iijima, Akiko Watanabe
  • Patent number: 9400247
    Abstract: An automatic analyzer has a multi-wavelength light source that irradiates a reaction cuvette containing a liquid mixture of a sample to be analyzed and a reagent. A transmitted-light quantity detector detects the amount of light transmitted through the reaction cuvette and internal contents of the reaction cuvette. A single-wavelength light source irradiates the reaction cuvette with single-wavelength light; and a transmitted-light quantity detector detects the amount of single-wavelength light scattered from the reaction cuvette.
    Type: Grant
    Filed: February 12, 2013
    Date of Patent: July 26, 2016
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Kotaro Yamashita, Masahiko Iijima
  • Publication number: 20160077119
    Abstract: The automatic analysis device includes an analysis unit that corrects, based on a measured value at the time of a first light amount measurement with water dispensed in the reaction cell before the sample is dispensed therein; a measured value at the time of a second light amount measurement after the sample and a preprocessing reagent are dispensed into the reaction cell; a liquid amount in the reaction cell at the time of the second light amount measurement; and a liquid amount in the reaction cell at the time of a third light amount measurement after the reaction reagent has been dispensed into the reaction cell and before the reaction reagent and the substance to be measured react with each other.
    Type: Application
    Filed: June 5, 2014
    Publication date: March 17, 2016
    Inventors: Sakuichiro ADACHI, Hajime YAMAZAKI, Masahiko IIJIMA, Shigeki MATSUBARA
  • Publication number: 20150219556
    Abstract: To enable determination of if there is an influence of foreign-body reactions on the result of quantitative determination conducted with a scattered light measurement method. Proposed is an automatic analysis device including a light source configured to irradiate a reaction solution with light, a plurality of light receivers configured to receive scattered light generated from the reaction solution at different light-receiving angles, a first data processing unit configured to process reaction process data measured by one of the light receivers to quantitatively determine a concentration of a substance in the reaction solution, and a second data processing unit configured to determine if the quantitative determination of the concentration of the substance has been performed normally on the basis of a ratio of a plurality of computed values, the plurality of computed values having been calculated from a plurality of pieces of reaction process data measured by the respective light receivers.
    Type: Application
    Filed: June 14, 2013
    Publication date: August 6, 2015
    Inventors: Sakuichiro Adachi, Hajime Yamazaki, Masahiko Iijima
  • Publication number: 20150204794
    Abstract: An automatic analyzer which can reduce the effort necessary for conducting a test of limit of detection/limit of quantification properties and managing the test results is provided. Operation condition-setting means for conducting an evaluation test for at least one of a limit of detection and a limit of quantification for each measurement item, determination condition-setting means for setting a determination condition of the evaluation test, and a calculation unit for obtaining a measurement result of a dilution series containing different dilution concentrations by controlling the sample-dispensing mechanism, the reagent-dispensing mechanism and the measurement unit based on the set operation condition, and calculating a test result of the evaluation test from the measurement result of the dilution series based on the set determination condition are disposed.
    Type: Application
    Filed: July 8, 2013
    Publication date: July 23, 2015
    Inventors: Masahiko Iijima, Akihisa Makino, Manabu Ando
  • Publication number: 20150104351
    Abstract: A high-throughput automatic analyzer integrates a biochemical analysis section and a blood coagulation analysis section. The analyzer is capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk; a first reagent dispensing mechanism that dispenses a reagent to reaction cells on the reaction disk; a photometer that irradiates a reaction solution in the reaction cell with light; a reaction cell cleaning mechanism; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to detect transmitted or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.
    Type: Application
    Filed: May 24, 2013
    Publication date: April 16, 2015
    Inventors: Akihisa Makino, Hajime Yamazaki, Keiko Yoshikawa, Manabu Ando, Masahiko Iijima
  • Publication number: 20150033831
    Abstract: An automatic analyzer has a multi-wavelength light source that irradiates a reaction cuvette containing a liquid mixture of a sample to be analyzed and a reagent. A transmitted-light quantity detector detects the amount of light transmitted through the reaction cuvette and internal contents of the reaction cuvette. A single-wavelength light source irradiates the reaction cuvette with single-wavelength light; and a transmitted-light quantity detector detects the amount of single-wavelength light scattered from the reaction cuvette.
    Type: Application
    Filed: February 12, 2013
    Publication date: February 5, 2015
    Inventors: Kotaro Yamashita, Masahiko Iijima
  • Publication number: 20140356964
    Abstract: An automatic analyzer detects measurement value abnormalities stemming from reaction process anomalies caused by the presence of foreign matter or bubbles. It is determined whether the results of concentration calculation based on light quantity data from multiple target detectors each fall within an applicable determination range. If the results fall within the determination range, an average value of the results of concentration calculation with the target detectors is calculated, and if not, an out-of-determination-range flag is given. A default fluctuation range is retrieved regarding the average value of the results of concentration calculation. The fluctuation range of the results of concentration calculation with the multiple target detectors is calculated.
    Type: Application
    Filed: November 22, 2012
    Publication date: December 4, 2014
    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Akihisa Makino, Masahiko Iijima, Akiko Watanabe
  • Patent number: 8153332
    Abstract: Fuel cells 100 of the invention are operable at a temperature of about 500° C. The unit cell has a solid oxide electrolyte layer formed on a hydrogen separable metal layer. An anode has a catalyst supported thereon to accelerate a reforming reaction of methane. A fuel gas is produced by reforming a hydrocarbon-containing material in a reformer 20. Setting a lower reaction temperature enables production of the fuel gas containing both methane and hydrogen. In the fuel cells 100 receiving a supply of the fuel gas, the reforming reaction of methane contained in the fuel gas proceeds simultaneously with consumption of hydrogen contained in the fuel gas. This methane reforming reaction is endothermic to absorb heat produced in the process of power generation and thereby equalizes the operation temperature of the fuel cells 100.
    Type: Grant
    Filed: March 10, 2004
    Date of Patent: April 10, 2012
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventors: Satoshi Aoyama, Satoshi Iguchi, Koichi Numata, Masahiko Iijima, Naoki Ito
  • Patent number: 7833675
    Abstract: A proton conductor includes a water-soluble electrolyte membrane with proton conductivity and a proton-conductive ceramic that is provided on at least one surface of the water-soluble electrolyte membrane.
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: November 16, 2010
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventor: Masahiko Iijima
  • Patent number: 7829235
    Abstract: First, a solid-state electrolyte layer that has conductivity for ions of one of hydrogen and oxygen is formed. After that, a dense layer made of an electrode material that has electron conductivity, catalyst activity to accelerate the electrochemical reaction, and a characteristic of allowing permeation of ions and/or atoms of the other one of hydrogen and oxygen is formed on a surface of the electrolyte layer. Then, a fuel cell structure that includes the electrolyte layer and the dense layer is built. After that, the electrochemical reaction is caused to progress by supplying a fuel and oxygen to the fuel cell structure, so that in the dense layer, many micropores extending through the dense layer in the film thickness direction are created due to the generated water that is created between the electrolyte layer and the dense layer.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: November 9, 2010
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventor: Masahiko Iijima
  • Publication number: 20100183938
    Abstract: A fuel cell (100) includes: a fuel electrode (10) that is tubular in form and is made of a hydrogen permeable metal; a solid electrolyte membrane (20) that has proton conductivity and is formed on the fuel electrode; and an oxygen electrode (40) that is provided on the solid electrolyte membrane (20), and that is disposed opposite to the fuel electrode (10) across the solid electrolyte membrane (20).
    Type: Application
    Filed: July 9, 2008
    Publication date: July 22, 2010
    Inventors: Masahiko IIjima, Naoki Ito
  • Patent number: 7615297
    Abstract: A fuel cell of the invention has a hydrogen permeable metal layer, which is formed on a plane of an electrolyte layer that has proton conductivity and includes a hydrogen permeable metal. The fuel cell includes a higher temperature zone and a lower temperature zone that has a lower temperature than the higher temperature zone. The hydrogen permeable metal layer includes a lower temperature area A corresponding to the lower temperature zone and a higher temperature area B corresponding to the higher temperature zone. The lower temperature area A and the higher temperature area B have different settings of composition and/or layout of components. This arrangement effectively prevents potential deterioration of cell performance due to an uneven distribution of internal temperature of the fuel cell including the hydrogen permeable metal layer.
    Type: Grant
    Filed: December 16, 2004
    Date of Patent: November 10, 2009
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventors: Satoshi Aoyama, Naoki Ito, Masahiko Iijima, Shigeru Ogino, Kenji Kimura, Hiromichi Sato, Yasuhiro Izawa, Satoshi Iguchi
  • Publication number: 20090233151
    Abstract: A fuel cell (100) is provided that includes a hydrogen separation membrane (10), an electrolyte membrane (20), provided on the hydrogen separation membrane, that has a proton conductivity and includes a perovskite type electrolyte having a A1-xA?xB1-y-zB?yB?zO3 structure, and a cathode (30) provided on the electrolyte membrane. The tolerance factor T of the perovskite type electrolyte satisfies 0.940?T?0.996.
    Type: Application
    Filed: May 23, 2007
    Publication date: September 17, 2009
    Inventor: Masahiko Iijima
  • Publication number: 20090220846
    Abstract: A proton conductor includes a water-soluble electrolyte membrane with proton conductivity and a proton-conductive ceramic that is provided on at least one surface of the water-soluble electrolyte membrane.
    Type: Application
    Filed: February 19, 2009
    Publication date: September 3, 2009
    Applicant: Toyota Jidosha Kabushiki Kaisha
    Inventor: Masahiko Iijima
  • Publication number: 20090220383
    Abstract: Disclosed herein is an automatic analyzer that can eliminate the generation of air bubbles of dissolved gas in a liquid circulating in a thermostat bath enabling stable photometry. A degasifier for removing the dissolved gas in the liquid and a bypass passage for ensuring a flow rate required for temperature control of the circulating liquid are provided in a passage for temperature-controlled liquid circulating in the thermostat bath. The automatic analyzer can reduce the dissolved gas concentration to a level at which air bubbles of the dissolved gas in the liquid do not appear while maintaining a flow rate required for temperature control of the liquid circulating in the thermostat bath, thus eliminating air bubbles passing through the light flux during photometry and accordingly enabling stable photometry.
    Type: Application
    Filed: January 16, 2009
    Publication date: September 3, 2009
    Inventors: Masahiko IIJIMA, Kazumi Kusano, Shinji Azuma
  • Publication number: 20090155657
    Abstract: A hydrogen permeable film (1) includes a hydrogen permeable base material (2) including V or a V alloy, a Pd film (3) including Pd or a Pd alloy and having hydrogen permeability, and an intermediate layer (4) provided between the hydrogen permeable base material (2) and the Pd film (3) and including a first intermediate layer (5) in contact with the hydrogen permeable base material (2) and a second intermediate layer (6) in contact with the Pd film (3). The first intermediate layer (5) includes at least one selected from the group consisting of Ta, Nb and an alloy thereof and the second intermediate layer (6) includes at least one selected from the group consisting of a Group 8 element, a Group 9 element, a Group 10 element and an alloy thereof and has a thickness of 1-100 nm. A fuel battery includes a proton conductive film on a Pd film of such a hydrogen permeable film.
    Type: Application
    Filed: September 21, 2006
    Publication date: June 18, 2009
    Inventors: Osamu Mizuno, Masahiko Iijima
  • Patent number: 7491462
    Abstract: The invention provides an electrolyte membrane that allows an operating temperature of a solid polymer membrane fuel cell to be raised and an operating temperature of a solid oxide fuel cell to be lowered. This electrolyte membrane can be used in a fuel cell that is operable in an intermediate temperature range. The invention also provides a fuel cell using such an electrolyte membrane. The electrolyte membrane has a hydrated electrolyte layer, and dense layers made of a hydrogen permeable material that are formed on both sides of this electrolyte layer. Both sides of the electrolyte membrane are coated with dense layers. Consequently, evaporation of moisture contained in the electrolyte layer is suppressed, and increase in the resistance of the membrane is inhibited. As a result, the range of the operating temperature of the fuel cell can be enlarged.
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: February 17, 2009
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventors: Naoki Ito, Masahiko Iijima, Satoshi Aoyama, Satoshi Iguchi, Koichi Numata
  • Publication number: 20080138679
    Abstract: A hydrogen generation device includes a catalyst; a sulfur-trap member; a soot-trap member; a pair of reformers; and a control portion. In each reformer, a reforming reaction is carried out to generate hydrogen-containing gas using gasoline and cathode off-gas on the catalyst, and an exothermic reaction is carried out to heat the catalyst using anode off-gas and air. The control portion executes a control such that the reactant and the exothermic material are alternately supplied to each reformer, whereby the reforming reaction and the exothermic reaction are alternately carried out in each reformer. A fuel cell system includes the hydrogen generation device.
    Type: Application
    Filed: April 4, 2006
    Publication date: June 12, 2008
    Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: Masahiko Iijima, Satoshi Iguchi, Satoshi Shiokawa