Abstract: The magnetic recording medium has a magnetic layer containing multiple nonmagnetic particles having a ratio, major axis length/minor axis length, of less than or equal to 1.5, the multiple nonmagnetic particles are present in the magnetic layer in a state where, when the depth to which each of the multiple nonmagnetic particles is embedded in the magnetic layer in observation of a sectional image picked up by SEM is denoted as b and the thickness of the magnetic layer as t, the average value of the ratio of b/t is less than or equal to 0.9, and the number of protrusions 5 nm or greater in height is 800 or greater and the number of protrusions 20 nm or greater in height is 20 or less as measured by AFM per an area 40 ?m×40 ?m on the magnetic layer side surface of the magnetic recording medium.

Abstract: The magnetic recording medium includes a non-magnetic support; a non-magnetic layer including a non-magnetic powder and a binding agent on the non-magnetic support; and a magnetic layer including a ferromagnetic powder, a binding agent, and a non-magnetic powder on the non-magnetic layer, in which a skewness Rsk obtained using an atomic force microscope in a measurement region of a surface of the magnetic layer having a size of 5 ?m×5 ?m is greater than 0, a maximum peak height Rmax is equal to or smaller than 30.0 nm, and the number of projections having a height equal to or greater than 10 nm is equal to or greater than 10, and a magnetic recording and reproducing device including: this magnetic recording medium; and a magnetic head.

Abstract: It is an object of the present invention to provide a pharmaceutical composition comprising an anti-fractalkine antibody that provides therapeutically effective improvement to Crohn's disease, after the administration thereof to a human subject, and a method for treating Crohn's disease. Provided is a pharmaceutical composition for treating Crohn's disease. The present pharmaceutical composition comprises an anti-fractalkine antibody and a pharmaceutically acceptable excipient, and is used, such that the anti-fractalkine antibody is intravenously administered to a human at a dose of at least 10 mg/kg of human body weight in a method for treating Crohn's disease.

Abstract: A manufacturing machine is capable of subtractive manufacturing and additive manufacturing for a workpiece. The manufacturing machine includes: a first headstock and a second headstock disposed in a first processing area and configured to hold a workpiece; a lower tool rest and a tool spindle disposed in the first processing area and configured to hold a tool to be used for subtractive manufacturing for the workpiece; an additive manufacturing head disposed in a second processing area; and a robot arm configured to hold a workpiece and transport the workpiece between the first processing area and the second processing area. The additive manufacturing head is configured to discharge a material toward the workpiece held by the robot arm during additive manufacturing for the workpiece. Accordingly, the manufacturing machine configured simply to be capable of subtractive manufacturing and additive manufacturing is provided.

Abstract: An object of the present invention is to provide a pharmaceutical composition comprising an anti-fractalkine antibody, and a method for treating rheumatoid arthritis using the pharmaceutical composition, wherein the pharmaceutical composition and the method bring about therapeutically effective amelioration in rheumatoid arthritis after administration to a human subject. The present invention provides a pharmaceutical composition for the treatment of rheumatoid arthritis. The pharmaceutical composition in a method for treating rheumatoid arthritis comprises an anti-fractalkine antibody and a pharmaceutically acceptable excipient and is used such that at least 100 mg per dose of the anti-fractalkine antibody is subcutaneously administered to a human in need thereof.

Abstract: A manufacturing machine is capable of additive manufacturing. The manufacturing machine includes: a connecting part configured to be connectable to a machine tool capable of subtractive manufacturing; and an additive manufacturing head configured to be positioned in a machining area of the machine tool and discharge a material, when the connecting part is connected to the machine tool. The manufacturing machine for additive manufacturing that can be installed at a low cost is thus provided.

Abstract: A manufacturing machine is capable of subtractive manufacturing and additive manufacturing for a workpiece. The manufacturing machine includes: a first headstock and a second headstock disposed in a machining area and configured to hold a workpiece; a tool spindle and a lower tool rest disposed in the machining area and configured to hold a tool to be used for subtractive manufacturing for the workpiece: an additive manufacturing head configured to discharge a material during additive manufacturing for the workpiece a workpiece gripper configured to grip the workpiece during transportation of the workpiece into and out of the machining area; and a robot arm on which the additive manufacturing head and the workpiece gripper are mountable. Accordingly, the manufacturing machine improving the productivity in the simple and easy manner is provided.

Abstract: A workpiece processing method is a method for successively processing a plurality of workpieces including a first workpiece and a second workpiece in a single machining area. The workpiece processing method includes: performing additive manufacturing on the second workpiece in the machining area; and performing subtractive manufacturing on the first workpiece in the machining area while keeping on standby the second workpiece on which additive manufacturing is performed. In this way, the workpiece processing method with improved productivity is provided.

Abstract: The magnetic tape has a nonmagnetic layer, a magnetic layer, and a backcoat layer; with one or both of the magnetic layer and nonmagnetic layer comprising at least one type of lubricant; with the backcoat layer comprising at least one type of lubricant; with a surface lubricant index as measured on a surface of the magnetic layer ranging from 1.00 to 4.00; and with a state of a presence of indentations on the surface of the magnetic layer satisfying condition 1 and condition 2: condition 1: a number of indentations greater than or equal to 5 nm and less than 10 nm in depth of 5 to 1,000 per 350 ?m×260 ?m area; and condition 2: a number of indentations greater than or equal to 10 nm in depth of less than or equal to 100 per 350 ?m×260 ?m area.

Abstract: An electro-optical modulator includes a substrate 201; an optical waveguide formed of a silicon-containing i-type amorphous semiconductor 204 on the substrate; and a silicon-containing p-type semiconductor layer 203 and a silicon-containing n-type semiconductor layer 205 arranged apart from each other with the silicon-containing optical waveguide formed of an i-type amorphous semiconductor 204 interposed therebetween and constituting optical waveguides together with the silicon-containing optical waveguide formed of an i-type amorphous semiconductor. The silicon-containing p-type semiconductor layer 203 and/or silicon-containing n-type semiconductor layer 205 area crystalline semiconductor layer.

Abstract: An optical semiconductor device in which a first optical waveguide 407 comprising a silicon-containing amorphous semiconductor layer and a second optical waveguide 409 containing a silicon-containing i-type semiconductor layer as a constituent element are disposed in different layers in a range in which optical interaction can occur. An electro-optical modulator 409 having a pin junction structure comprising a p-type semiconductor layer 403, an i-type semiconductor layer 404, and an n-type semiconductor layer 405 is provided to at least a portion of the second optical waveguide 409, and the index of refraction of the second optical waveguide is varied by the electro-optical modulator, whereby light waves propagated through the first optical waveguide are modulated.

Abstract: The magnetic recording medium has a magnetic layer containing multiple nonmagnetic particles having a ratio, major axis length/minor axis length, of less than or equal to 1.5, the multiple nonmagnetic particles are present in the magnetic layer in a state where, when the depth to which each of the multiple nonmagnetic particles is embedded in the magnetic layer in observation of a sectional image picked up by SEM is denoted as b and the thickness of the magnetic layer as t, the average value of the ratio of b/t is less than or equal to 0.9, and the number of protrusions 5 nm or greater in height is 800 or greater and the number of protrusions 20 nm or greater in height is 20 or less as measured by AFM per an area 40 ?m×40 ?m on the magnetic layer side surface of the magnetic recording medium.

Abstract: An aspect of the present invention relates to a method of manufacturing hexagonal ferrite magnetic powder. The method of manufacturing hexagonal ferrite magnetic powder comprises wet processing hexagonal ferrite magnetic particles obtained following acid treatment in a water-based solvent to prepare an aqueous magnetic liquid satisfying relation (1) relative to an isoelectric point of the hexagonal ferrite magnetic particles: pH0?pH*?2.5, wherein, pH0 denotes the isoelectric point of the hexagonal ferrite magnetic particles and pH* denotes a pH of the aqueous magnetic liquid, which is a value of equal to or greater than 2.0, adding a surface-modifying agent comprising an alkyl group and a functional group that becomes an anionic group in the aqueous magnetic liquid to the aqueous magnetic liquid to subject the hexagonal ferrite magnetic particles to a surface-modifying treatment, and removing the water-based solvent following the surface-modifying treatment to obtain hexagonal ferrite magnetic particles.

Abstract: An optical semiconductor device in which a first optical waveguide 407 comprising a silicon-containing amorphous semiconductor layer and a second optical waveguide 409 containing a silicon-containing i-type semiconductor layer as a constituent element are disposed in different layers in a range in which optical interaction can occur. An electro-optical modulator 409 having a pin junction structure comprising a p-type semiconductor layer 403, an i-type semiconductor layer 404, and an n-type semiconductor layer 405 is provided to at least a portion of the second optical waveguide 409, and the index of refraction of the second optical waveguide is varied by the electro-optical modulator, whereby light waves propagated through the first optical waveguide are modulated.

Abstract: An object of the present invention is to provide an electro-optical modulator that allows high-speed carrier injection into a silicon-containing i-type amorphous semiconductor, particularly a-Si:H, and has little optical loss. An electro-optical modulator comprises: a substrate 201; an optical waveguide comprising a silicon-containing i-type amorphous semiconductor 204 formed on the substrate; and a silicon-containing p-type semiconductor layer 203 and a silicon-containing n-type semiconductor layer 205 arranged apart from each other with the silicon-containing optical waveguide comprising an i-type amorphous semiconductor 204 interposed therebetween and constituting optical waveguides together with the silicon-containing optical waveguide comprising an i-type amorphous semiconductor. The silicon-containing p-type semiconductor layer 203 and/or silicon-containing n-type semiconductor layer 205 are a crystalline semiconductor layer.

Abstract: The magnetic tape has a nonmagnetic layer, a magnetic layer, and a backcoat layer; with one or both of the magnetic layer and nonmagnetic layer comprising at least one type of lubricant; with the backcoat layer comprising at least one type of lubricant; with a surface lubricant index as measured on a surface of the magnetic layer ranging from 1.00 to 4.00; and with a state of a presence of indentations on the surface of the magnetic layer satisfying condition 1 and condition 2: condition 1: a number of indentations greater than or equal to 5 nm and less than 10 nm in depth of 5 to 1,000 per 350 ?m×260 ?m area; and condition 2: a number of indentations greater than or equal to 10 nm in depth of less than or equal to 100 per 350 ?m×260 ?m area.

Abstract: A method is provided for processing a silicon-based wire optical waveguide, by which an optical transmission loss of the silicon-based wire optical waveguide due to ion irradiation with high energy is suppressed, and an end portion of the silicon-based wire optical waveguide that is three-dimensionally curved in a self-aligning manner is obtained. According to the method a protective film is selectively formed on the silicon-based wire optical waveguide exclusive of the end portion of the silicon-based wire optical waveguide; and ions are implanted to the silicon-based wire optical waveguide in a particular direction, so as to curve the end portion of the silicon-based wire optical waveguide to the particular direction in a self-alignment manner.

Abstract: There is provided a processing machine and a processing machine line for which it is easy for an operator to view a screen display, including an operation panel with a free vertical and horizontal posture of a display in which a longitudinal dimension and a lateral dimension are different, in which a first display aspect which displays one screen that is displayed on the display and a second display aspect which is disposed lined up with two screens are switched. Switch buttons are set in order to perform switching between the first display aspect screen and the second display aspect screen, and the first display aspect screen and the second display aspect screen are mutually switched by operating the switching button, and during the switching, are rotated 90° with respect to the display.

Abstract: An interlayer light wave coupling device includes a substrate; a first core disposed on the substrate and having a first acute structure; a third core spatially set apart from the first core and having a second acute structure; and a second core disposed between the first core and the third core and having a smaller index of refraction than the first core and the third core. The acute structures of the first core and the third core are disposed so as to have no overlap as viewed from above.

Abstract: An interlayer light wave coupling device includes a substrate; a first core disposed on the substrate and having a first acute structure; a third core spatially set apart from the first core and having a second acute structure; and a second core disposed between the first core and the third core and having a smaller index of refraction than the first core and the third core. The acute structures of the first core and the third core are disposed so as to have no overlap as viewed from above.