Abstract: A radiotherapy device controller includes: a visual line calculator configured to calculate a visual line based on a position on a transmissive image imaged using a radiation penetrating a subject, a specific part of the subject being shown at the position; a position calculator configured to calculate a position of the specific part based on a position of a trajectory of the specific part and a position of the visual line; and an emitter configured to control a radiation emitter that emits a therapeutic radiation, so that the therapeutic radiation penetrates at the position of the specific part.

Abstract: The present invention provides a rare earth magnet, which is formed through at least hot molding, the rare earth magnet containing grains including an R2X14B phase as a main phase, and a grain boundary phase surrounding peripheries of the grains, in which R is at least one element selected from the group consisting of Nd, Pr, Dy, Tb and Ho, and X is Fe or Fe with a part being substituted by Co; in which an element RH is more concentrated in the grain boundary phase than in the grains, in which the element RH is at least one element selected from the group consisting of Dy, Tb and Ho; and the element RH is present with a substantially constant concentration distribution from the surface part of the magnet to the central part of the magnet.

Abstract: Provided is a technique for observing in real time the state of a disease condition in a tissue of an animal or the state of a functionally adverse condition which is a prelude to the disease condition without injuring the animal. This can be achieved by the use of a gene construct having a reporter gene integrated under the control of a hypoxia responsible promoter an ODD domain (oxygen dependent degradation domain) integrated upstream to the reporter gene.

Abstract: To identify a domain in HIF-1? protein, which participates in stabilization of a fused protein, DNA encoding the following polypeptide (A) or (B) is provided: (A) a polypeptide having the amino acid sequence of SEQ ID NO: 1 (B) a polypeptide having an amino acid sequence comprising at least 16 amino acid residues in the amino acid sequence of SEQ ID NO: 1, and imparting stability dependent on an oxygen concentration to other protein in a cell harboring a fused protein, when the polypeptide is fused with a nuclear localization signal and the other protein to form the fused protein.

Abstract: The present invention provides a rare earth magnet, which is formed through at least hot molding, the rare earth magnet containing grains including an R2X14B phase as a main phase, and a grain boundary phase surrounding peripheries of the grains, in which R is at least one element selected from the group consisting of Nd, Pr, Dy, Tb and Ho, and X is Fe or Fe with a part being substituted by Co; in which an element RH is more concentrated in the grain boundary phase than in the grains, in which the element RH is at least one element selected from the group consisting of Dy, Tb and Ho; and the element RH is present with a substantially constant concentration distribution from the surface part of the magnet to the central part of the magnet.

Abstract: In an electric bulb wherein a pair of lead-in wires 14a, 14b for suspending a filament 16 is supported with a space by heating and melting a glass bead 15 made of glass, a concave portions 15a, 15b are formed at the contact portion of an outer surface of the glass bead 15 and the lead-in wires 14a, 14b, so that rising of the molten glass along the lead-in wires is suppressed. Thus, break of filament 16 owing to the generation of glass bead chippings or minute cracks is avoided, thereby providing a electric bulb having high production yield and high reliability.

Abstract: A method for the production of a material for cancer treatment, which comprises preparing a first aqueous acidic to neutral solution containing a metal to be insoluble in an alkaline solution and a carboxylic acid amide, and a second aqueous solution containing an enzyme catalyzing hydrolysis of the carboxylic acid amide and an organic polymer becoming gel by reaction with a component of the first aqueous solution or energy application from the outside, adding the second aqueous solution to the first aqueous solution, and drying. The material for cancer treatment is easy to be transported by a catheter and stay in a diseased part.

Abstract: Exothermic elements (30) for hyperthermic treatment having, as a main component thereof, ferromagnetic layers (20) coated outside nucleus particles (10). The ferromagnetic layers (20) comprise an oxide having a magnetic domain structure mainly formed of at least one of a single domain and a pseudo-single domain. These exothermic elements for hyperthermic treatment may be manufactured by heating after depositing iron hydroxide on the nucleus particles (10) by a liquid phase process.

Abstract: In an electric bulb wherein a pair of lead-in wires 14a, 14b for suspending a filament 16 is supported with a space by heating and melting a glass bead 15 made of glass, a concave portions 15a, 15b are formed at the contact portion of an outer surface of the glass bead 15 and the lead-in wires 14a, 14b, so that rising of the molten glass along the lead-in wires is suppressed. Thus, break of filament 16 owing to the generation of glass bead chippings or minute cracks is avoided, thereby providing a electric bulb having high production yield and high reliability.