Patents by Inventor Masahiro KOTANI

Masahiro KOTANI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230086284
    Abstract: A sample support used for ionizing a component of a sample includes: a substrate having a first surface, a second surface opposite the first surface, and a plurality of through-holes that are open on the first surface and on the second surface; a conductive layer provided on at least the first surface; and a cationizing agent provided in the plurality of through-holes to cationize the component with a predetermined atom.
    Type: Application
    Filed: January 15, 2021
    Publication date: March 23, 2023
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Masahiro KOTANI, Takayuki OHMURA, Akira TASHIRO
  • Publication number: 20230025534
    Abstract: A sample support is a sample support for sample ionization, including: a substrate formed with a plurality of through holes opening to a first surface and a second surface on a side opposite to the first surface; a conductive layer provided not to block the through hole in the first surface; and a reinforcement member disposed inside a part of the plurality of through holes.
    Type: Application
    Filed: October 3, 2022
    Publication date: January 26, 2023
    Inventors: Miu TAKIMOTO, Takayuki Ohmura, Masahiro Kotani
  • Patent number: 11521843
    Abstract: A sample support is a sample support for sample ionization, including: a substrate formed with a plurality of through holes opening to a first surface and a second surface on a side opposite to the first surface; a conductive layer provided not to block the through hole in the first surface; and a reinforcement member disposed inside a part of the plurality of through holes.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: December 6, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Miu Takimoto, Takayuki Ohmura, Masahiro Kotani
  • Patent number: 11442039
    Abstract: Provided is a sample support body that includes: a substrate having a first surface and a second surface opposite to each other; and a conductive layer provided on at least the first surface. A plurality of through-holes, which open to the second surface and a third surface of the conductive layer which is located on a side opposite to the substrate, are formed in the substrate and the conductive layer. At least one of the second surface and the third surface is subjected to surface treatment for providing a difference in an affinity with water between a surface close to the second surface and a surface close to the third surface.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: September 13, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Yasuhide Naito, Takayuki Ohmura, Masahiro Kotani
  • Publication number: 20220260528
    Abstract: Provided is a sample support body that includes a substrate, an ionization substrate, a support, and a frame. The ionization substrate has a plurality of measurement regions for dropping a sample on second surface. A plurality of through-holes that open in a first surface and the second surface are formed at least in the measurement regions of the ionization substrate. A conductive layer is provided on peripheral edges of the through-holes at least on the second surface. The frame has a wall provided on peripheral edges of the measurement regions on the second surface to separate the plurality of measurement regions when viewed in the direction in which the substrate and the ionization substrate face each other.
    Type: Application
    Filed: May 5, 2022
    Publication date: August 18, 2022
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Takayuki OHMURA, Masahiro KOTANI
  • Patent number: 11404256
    Abstract: A sample support body is for ionization of a sample. The sample support body includes a substrate including a first surface and a second surface on sides opposite to each other, and a conduction layer provided at least on the first surface. A plurality of through-holes opening on the first surface and the second surface are formed in an effective region of the substrate, the effective region being for ionizing components of the sample. A width of a second opening on the second surface side is larger than a width of a first opening on the first surface side in each of the plurality of through-holes.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: August 2, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Masahiro Kotani, Takayuki Ohmura
  • Publication number: 20220238317
    Abstract: A sample support is a sample support for sample ionization, including: a substrate formed with a plurality of through holes opening to a first surface and a second surface on a side opposite to the first surface; a conductive layer provided not to block the through hole in the first surface; and a frame body provided in a peripheral portion of the substrate to surround an ionization region in which a sample is ionized when viewed in a thickness direction of the substrate, in which a marker for recognizing a position in the ionization region is provided in the frame body.
    Type: Application
    Filed: April 12, 2022
    Publication date: July 28, 2022
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Miu TAKIMOTO, Takayuki OHMURA, Masahiro KOTANI
  • Publication number: 20220227674
    Abstract: A ceramic matrix composite includes a substrate which contains a fibrous body formed from a silicon carbide fiber, and a matrix which is formed in the substrate, and which contains RE3Al5O12, RE2Si2O7, and the balance being an oxide of RE, Al, and Si, or RE2SiO5, where the RE is Y or Yb.
    Type: Application
    Filed: April 7, 2022
    Publication date: July 21, 2022
    Applicant: IHI Corporation
    Inventors: Takeshi NAKAMURA, Hiroto HIRANO, Masahiro KOTANI, Takahiko SHINOHARA
  • Patent number: 11393667
    Abstract: A sample support body includes: a substrate having a first surface and a second surface opposite to each other; and a conductive layer provided on at least the first surface. A plurality of through-holes, which open to the second surface and to a third surface of the conductive layer which is locate at a side opposite to the substrate, are provided in the substrate and the conductive layer. A protective film having a higher affinity with water than the substrate is provided on the second surface, the third surface, and each inner surface of the plurality of through-holes.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: July 19, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Yasuhide Naito, Takayuki Ohmura, Masahiro Kotani
  • Publication number: 20220223396
    Abstract: A sample support is used for ionization of a sample. The sample support includes a film part having a first front surface and a first back surface, the film part being formed with a plurality of through-holes, and a support part defining a measurement region for ionizing the sample with respect to the film part and supporting the film part. The support part includes an inner portion having a second front surface and a second back surface, the film part being fixed to the inner portion, and an outer portion having a third front surface and a third back surface and extending along an outer edge of the inner portion. A difference generated between a position of the first front surface and a position of the third front surface in a thickness direction of the film part is smaller than a thickness of the film part.
    Type: Application
    Filed: April 1, 2020
    Publication date: July 14, 2022
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Akira TASHIRO, Masahiro KOTANI, Takayuki OHMURA
  • Publication number: 20220199387
    Abstract: A sample support body for ionization of a sample, including: a substrate having a first surface, a second surface on a side opposite to the first surface, and a plurality of through-holes opening on each of the first surface and the second surface; a conductive layer provided on the first surface; and a matrix crystal layer provided on at least one of the conductive layer and the second surface, in which the matrix crystal layer is formed of a plurality of matrix crystal grains so as to include a gap communicating the plurality of through-holes with an outside.
    Type: Application
    Filed: January 23, 2020
    Publication date: June 23, 2022
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Masahiro KOTANI, Takayuki OHMURA, Akira TASHIRO
  • Publication number: 20220189752
    Abstract: An ionization method includes: a first process of preparing a sample support body including an electrically insulating substrate having a first surface, a second surface on a side opposite to the first surface, and a plurality of through-holes opening on each of the first surface and the second surface and an electrically insulating frame attached to the substrate; a second process of mounting a sample on a mount surface of a mount portion and mounting the sample support body on the mount surface so that the second surface is in contact with the sample; and a third process of ionizing components of the sample that have moved to the first surface side via the plurality of through-holes by irradiating the first surface with charged-droplets and sucking the ionized components.
    Type: Application
    Filed: January 23, 2020
    Publication date: June 16, 2022
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Masahiro KOTANI, Takayuki OHMURA, Daisuke SAIGUSA
  • Publication number: 20220189757
    Abstract: A sample support body is a sample support body for ionization of a sample, including: a substrate having a first surface, a second surface on a side opposite to the first surface, and a plurality of through-holes opening on each of the first surface and the second surface; and a frame attached to the substrate, in which a thermal conductivity of the frame is 1.0 W/m·K or less.
    Type: Application
    Filed: January 23, 2020
    Publication date: June 16, 2022
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Masahiro KOTANI, Takayuki OHMURA
  • Patent number: 11360049
    Abstract: Provided is a sample support body that includes a substrate, an ionization substrate, a support, and a frame. The ionization substrate has a plurality of measurement regions for dropping a sample on second surface. A plurality of through-holes that open in a first surface and the second surface are formed at least in the measurement regions of the ionization substrate. A conductive layer is provided on peripheral edges of the through-holes at least on the second surface. The frame has a wall provided on peripheral edges of the measurement regions on the second surface to separate the plurality of measurement regions when viewed in the direction in which the substrate and the ionization substrate face each other.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: June 14, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Takayuki Ohmura, Masahiro Kotani
  • Patent number: 11355333
    Abstract: Provided is a sample support body that includes a substrate and an ionization substrate. The ionization substrate has a measurement region for dropping a sample on a second surface. A plurality of through-holes that open in a first surface and the second surface are formed in at least the measurement region of the ionization substrate. A conductive layer is provided on peripheral edges of the through-holes on at least the second surface. At least a part of the substrate which is adjacent to the ionization substrate is formed to enable the sample to move to the inside of the substrate.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: June 7, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Takayuki Ohmura, Masahiro Kotani
  • Patent number: 11348772
    Abstract: A sample support is a sample support for sample ionization, including: a substrate formed with a plurality of through holes opening to a first surface and a second surface on a side opposite to the first surface; a conductive layer provided not to block the through hole in the first surface; and a frame body provided in a peripheral portion of the substrate to surround an ionization region in which a sample is ionized when viewed in a thickness direction of the substrate, in which a marker for recognizing a position in the ionization region is provided in the frame body.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: May 31, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Miu Takimoto, Takayuki Ohmura, Masahiro Kotani
  • Publication number: 20220157588
    Abstract: The sample support includes a substrate having a plurality of through holes opened in a first surface and a second surface, a frame surrounding a measurement region of the substrate and supporting the substrate when viewed in a thickness direction of the substrate, and a protective layer disposed to face the first surface and having a facing portion facing the measurement region. A through hole penetrating in the thickness direction is formed in the facing portion. The through hole of the facing portion includes a narrow portion having a width smaller than an outer diameter of a tip of a pipette tip for dropping a sample solution into the measurement region.
    Type: Application
    Filed: December 11, 2019
    Publication date: May 19, 2022
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Masahiro KOTANI, Takayuki OHMURA, Akira TASHIRO
  • Publication number: 20220157587
    Abstract: The sample support is used for ionization of a sample contained in a sample solution dropped using a pipette tip. The sample support includes a substrate formed with a plurality of through holes opened in a first surface and a second surface, and a frame that is formed with a through hole penetrating in a thickness direction of the substrate so as to overlap a measurement region when viewed from the thickness direction and that is bonded to the first surface of the substrate. The through hole of the frame includes a narrow portion having a width smaller than the outer diameter of a tip of the pipette tip.
    Type: Application
    Filed: December 11, 2019
    Publication date: May 19, 2022
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Masahiro KOTANI, Takayuki OHMURA, Akira TASHIRO
  • Patent number: 11335546
    Abstract: A laser desorption/ionization method, includes: a first step of preparing a sample support body including a substrate on which a plurality of through holes opening to a first surface and a second surface facing each other are formed, a conductive layer provided on at least the first surface, and a solvent provided in the plurality of through holes with refractoriness in a vacuum; a second step of mounting a sample on a mounting surface of a mounting portion, and of disposing the sample support body on the sample such that the second surface is in contact with the sample; and a third step of ionizing a component of the sample that is mixed with the solvent and is moved to the first surface side from the second surface side through the through hole by irradiating the first surface with laser beam while applying a voltage to the conductive layer.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: May 17, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Yasuhide Naito, Takayuki Ohmura, Masahiro Kotani
  • Patent number: 11302522
    Abstract: A first-stage dynode is a first-stage dynode to be used in a photomultiplier tube, and includes a bottom wall portion and a pair of side wall portions extending from both end portions of the bottom wall portion in a predetermined direction to one side. An electron emission surface is formed by a bottom surface of the bottom wall portion on the one side and a pair of side surfaces of the pair of side wall portions on the one side, and each of the pair of side surfaces is a curved surface that is curved in a concave shape in a cross section parallel to the predetermined direction.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: April 12, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Yuki Nishimura, Masahiro Kotani, Takanori Ichinomiya