Patents by Inventor Masahiro Okada

Masahiro Okada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11979057
    Abstract: A cylindrical part of a rotor for an eddy current deceleration device of the present embodiment has a chemical composition consisting of, by mass %, C: 0.05 to 0.15%, Si: 0.10 to 0.40%, Mn: 0.50 to 1.00%, P: 0.030% or less, S: 0.030% or less, Mo: 0.20 to 1.00%, Nb: 0.020 to 0.060%, V: 0.040 to 0.080%, sol. Al: 0.030 to 0.100%, B: 0.0005 to 0.0050%, N: 0.003 to 0.010%, Cu: 0 to 0.20%, Ni: 0 to 0.20%, Cr: 0 to 0.10%, and the balance: Fe and impurities, and in which the total area fraction of martensite and bainite in a microstructure is more than 95.0%, and the number density of carbides having an equivalent circular diameter of 100 to 500 nm is 0.35 to 0.75 particles/?m2.
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: May 7, 2024
    Assignee: NIPPON STEEL CORPORATION
    Inventors: Nao Otaki, Hirokazu Okada, Yasutaka Noguchi, Kenji Imanishi, Masahiro Tasaka
  • Publication number: 20240141217
    Abstract: Provided is a resin film that has a stress integral value of greater than 10 MPa and 1000 MPa or less when uniaxially stretched at a tensile speed of 300 mm/min at 25° C. until it breaks. The resin film showing these properties is supple and durable.
    Type: Application
    Filed: February 28, 2022
    Publication date: May 2, 2024
    Inventors: Satoshi HONDA, Masahiro KUZE, Kenichi OKADA, Takayuki KUROKAWA, Jian Ping GONG
  • Patent number: 11893559
    Abstract: A unit has a bottom surface, and first and second flange portions. A mounting plate has a first hook portion to be engaged with the first flange portion to control movement of the unit, having been mounted onto an upper plate surface, toward a front side in a depth direction and in a height direction; a second hook portion to be engaged with the second flange portion to control movement of the unit, having been mounted onto the upper plate surface, toward the front side in the depth direction and in the height direction; and a locking portion releasably engaged with the second flange portion to allow movement of the unit, being inserted or removed on the upper plate surface in the depth direction, and to control movement of the unit, having been mounted onto the upper plate surface, toward a rear side in the depth direction.
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: February 6, 2024
    Assignee: NEC Platforms, Ltd.
    Inventors: Masahiro Okada, Tetsuya Tanabe
  • Publication number: 20240036223
    Abstract: Provided is a calibration method for a detector including a plurality of detecting elements each of which generates an electrical pulse signal with a peak value corresponding to an energy value of incident X-ray photons and counts a photon count for each peak value, including: applying a predetermined tube voltage to an X-ray tube for irradiating the detector with X-rays; acquiring the photon count for each peak value from each of the detecting elements; estimating a maximum peak value H within a range in which X-ray photons are detected and at which the peak value is maximum; and calculating, for each of the detecting elements, a calibration value that associates the tube voltage with the maximum peak value H.
    Type: Application
    Filed: March 12, 2021
    Publication date: February 1, 2024
    Inventors: Shuichiro YAMAMOTO, Masahiro OKADA, Masashi YAMASAKI, Daisuke HASHIMOTO, Hiroaki HAYASHI, Natsumi KIMOTO
  • Publication number: 20220275534
    Abstract: The purpose of the present invention is to provide a method of producing a peptide library including a step of bringing a peptide library including peptides having an amino acid sequence containing at least one Trp or derivative thereof into contact with a prenylation enzyme and prenylating at least a part of amino acid residues contained in at least some of the peptides.
    Type: Application
    Filed: October 17, 2019
    Publication date: September 1, 2022
    Inventors: Hiroaki Suga, Yuki Goto, Ikuro Abe, Masahiro Okada, Sumika Inoue
  • Publication number: 20220265714
    Abstract: The present disclosure includes a method of producing a cell population containing Chimeric Antigen Receptor (CAR)-expressing immune cells, comprising co-culturing CAR-expressing immune cells and cells expressing a target antigen of the CAR, wherein the CAR-expressing immune cells are cells into which a CAR gene has been introduced and the target antigen-expressing cells are normal blood cells that have been engineered to express the target antigen.
    Type: Application
    Filed: July 30, 2020
    Publication date: August 25, 2022
    Applicants: SHINSHU UNIVERSITY, KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION, BrightPath Biotherapeutics Co., Ltd.
    Inventors: Yozo Nakazawa, Shigeki YAGYU, Miyuki TANAKA, Kayoko NAKAMURA, Masahiro OKADA, Makoto KONDO, Tomokuni SHIGEURA, Shogo HIROTA
  • Publication number: 20220092569
    Abstract: A unit has a bottom surface, and first and second flange portions. A mounting plate has a first hook portion to be engaged with the first flange portion to control movement of the unit, having been mounted onto an upper plate surface, toward a front side in a depth direction and in a height direction; a second hook portion to be engaged with the second flange portion to control movement of the unit, having been mounted onto the upper plate surface, toward the front side in the depth direction and in the height direction; and a locking portion releasably engaged with the second flange portion to allow movement of the unit, being inserted or removed on the upper plate surface in the depth direction, and to control movement of the unit, having been mounted onto the upper plate surface, toward a rear side in the depth direction.
    Type: Application
    Filed: January 14, 2020
    Publication date: March 24, 2022
    Applicant: NEC Platforms, Ltd.
    Inventors: Masahiro OKADA, Tetsuya TANABE
  • Patent number: 11099141
    Abstract: A higher accuracy beam hardening correction with a low calculation load is performed with objects whose elements have a wider range of effective atomic numbers Zeff, thereby contributing to presentation of more quantitative X-ray images. Of two or more X-ray energy bins, two X-ray bins are selected to normalize X-ray attenuation amount ?t in those bins such that one or more normalized X-ray attenuation amounts are obtained at each pixel areas. From reference information indicating a theoretical relationship of correspondence between the normalized X-ray attenuation amounts and effective atomic numbers of elements, one ore more effective atomic numbers are estimated every pixel area. Among the one or more effective atomic numbers (ZHigh, ZLow) and an effective atomic number (Zm) preset for the beam hardening correction, two or more atomic numbers are subjected to their equality determination.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: August 24, 2021
    Assignee: JOB Corporation
    Inventors: Tsutomu Yamakawa, Shuichiro Yamamoto, Masahiro Okada
  • Patent number: 11016040
    Abstract: In a data processing apparatus, image data are calculated based on photon counts of an X-ray beam transmitted through an object. Based on the image data, X-ray attenuation information is calculated. The attenuation information includes i) inherent information inherently depending on a type or a property of the object, the inherent information being indicated by a quantity of a vector in an n-dimensional coordinate whose dimension is equal in number to the n-piece energy ranges; and ii) associated information being associated with the inherent information and depending on a length of a path along which the X-ray beam passes though the object. From the attenuation information, only the inherent information is produced which is independent of the associated information. Scattering points corresponding to the inherent information are calculated to be mapped in the n-dimensional coordinate or in a coordinate whose dimension is less than the n-dimensional coordinate.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: May 25, 2021
    Assignee: JOB CORPORATION
    Inventors: Tsutomu Yamakawa, Shuichiro Yamamoto, Masahiro Okada
  • Patent number: 11009470
    Abstract: Based on counts detected by a photon counting detector, a characteristic of X-ray attenuation amounts ?t is acquired for each X-ray energy bin. This characteristic is defined by a plurality of mutually different known thicknesses t and linear attenuation coefficients in the X-ray transmission direction. This substance is composed of a material which is included in an object and which is the same in type as the object or which can be regarded as being similar to the object in terms of the effective atomic number. Correcting data for replacing the characteristic of the X-ray attenuation amounts ?t by a linear target characteristic are calculated. The linear target characteristic is set to pass through the origin of a two-dimensional coordinate having a lateral axis assigned to thicknesses t and a longitudinal axis assigned to the X-ray attenuation amounts ?t. The correcting data are calculated for each X-ray energy bin.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: May 18, 2021
    Assignee: JOB CORPORATION
    Inventors: Tsutomu Yamakawa, Shuichiro Yamamoto, Masahiro Okada
  • Publication number: 20200249179
    Abstract: A higher accuracy beam hardening correction with a low calculation load is performed with objects whose elements have a wider range of effective atomic numbers Zeff, thereby contributing to presentation of more quantitative X-ray images. Of two or more X-ray energy bins, two X-ray bins are selected to normalize X-ray attenuation amount ?t in those bins such that one or more normalized X-ray attenuation amounts are obtained at each pixel areas. From reference information indicating a theoretical relationship of correspondence between the normalized X-ray attenuation amounts and effective atomic numbers of elements, one ore more effective atomic numbers are estimated every pixel area. Among the one or more effective atomic numbers (ZHigh, ZLow) and an effective atomic number (Zm) preset for the beam hardening correction, two or more atomic numbers are subjected to their equality determination.
    Type: Application
    Filed: October 26, 2018
    Publication date: August 6, 2020
    Inventors: Tsutomu YAMAKAWA, Shuichiro YAMAMOTO, Masahiro OKADA
  • Patent number: 10697904
    Abstract: An X-ray apparatus includes a two-dimensional pixel array having rectangular pixels outputting an electrical signal responsively to an incident X-ray photon. This array has a row direction oblique to a scan direction. When viewing in the scan direction, a pixel group is provided solely or repeatedly, the pixel group being composed of “M rows × N pieces” of pixels (M is a positive integer equal to or larger than 1, N is a positive integer equal to or larger than 2, and M and N have a relationship of prime numbers). The pixel group occupies a quadrangle whose diagonal line is parallel with the scan direction. In a memory space, the frame data from the pixels are converted to frame data in a Cartesian coordinate system having a row direction which is in parallel with the scan direction and a column direction orthogonal to the row direction.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: June 30, 2020
    Assignee: JOB CORPORATION
    Inventors: Tsutomu Yamakawa, Shuichiro Yamamoto, Masashi Yamasaki, Masahiro Okada
  • Patent number: 10502698
    Abstract: The type and/or properties of a substance included in an object is identified highly accurately regardless of the thickness of the substance. A data processing apparatus processes counts detected at each of pixels of a photo counting detector in each of a plurality of energy ranges of X-rays. The X-rays are radiated from an X-ray tube, and transmitted through an object. The apparatus calculates an image of the object based on the counts, and sets a region of interest on the image. The apparatus further removes, from the image, pixel information showing a background present in the region of interest, and calculates, pixel by pixel, inherent information inherent to the substance, based on the counts detected at each of the respective pixels in each of the energy ranges of the X-rays in the region of interest. The inherent information indicates a transmission characteristic inherent to the X-rays.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: December 10, 2019
    Assignee: JOB CORPORATION
    Inventors: Tsutomu Yamakawa, Shuichiro Yamamoto, Yoshiharu Obata, Masashi Yamasaki, Masahiro Okada
  • Publication number: 20190162679
    Abstract: In a data processing apparatus, image data are calculated based on photon counts of an X-ray beam transmitted through an object. Based on the image data, X-ray attenuation information is calculated. The attenuation information includes i) inherent information inherently depending on a type or a property of the object, the inherent information being indicated by a quantity of a vector in an n-dimensional coordinate whose dimension is equal in number to the n-piece energy ranges; and ii) associated information being associated with the inherent information and depending on a length of a path along which the X-ray beam passes though the object. From the attenuation information, only the inherent information is produced which is independent of the associated information. Scattering points corresponding to the inherent information are calculated to be mapped in the n-dimensional coordinate or in a coordinate whose dimension is less than the n-dimensional coordinate.
    Type: Application
    Filed: May 16, 2018
    Publication date: May 30, 2019
    Inventors: Tsutomu YAMAKAWA, Shuichiro YAMAMOTO, Masahiro OKADA
  • Publication number: 20190017943
    Abstract: Circuitry for converting frame data outputted from an obliquely arranged detector, to frame data in a coordinate system for reconstruction is avoided from becoming larger in size and an processing amount is reduced. An X-ray apparatus is provided with a two-dimensional pixel array, the two-dimensional pixel array having a plurality of rectangular pixels, having a predetermined size and outputting an electrical signal in response to an incident X-ray photon. The pixels of the array are arranged in the row and column directions in a first Cartesian coordinate system. The row direction is set obliquely to a scan direction.
    Type: Application
    Filed: March 27, 2017
    Publication date: January 17, 2019
    Inventors: Tsutomu YAMAKAWA, Shuichiro YAMAMOTO, Masashi YAMASAKI, Masahiro OKADA
  • Patent number: 10072883
    Abstract: According to one embodiment, a heat source unit apparatus includes air heat exchangers, each includes a plurality of fins arranged at prescribed intervals, heat exchanging pipes penetrating the fins, and bent strips extending at sides and bent in the same direction, and a heat exchange module includes two air heat exchangers, each having the bent strips opposed to those of the other air heat exchanger, the air heat exchangers being inclined such that lower edges are close to each other and upper edges are spaced apart, whereby the heat exchange module is shaped like a letter V as seen from side.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: September 11, 2018
    Assignee: Toshiba Carrier Corporation
    Inventors: Hideki Tanno, Masahiro Okada, Kenjiro Matsumoto, Takamitsu Ishiguro
  • Publication number: 20180214113
    Abstract: Based on counts detected by a photon counting detector, a characteristic of X-ray attenuation amounts ?t is acquired for each X-ray energy bin. This characteristic is defined by a plurality of mutually different known thicknesses t and linear attenuation coefficients in the X-ray transmission direction. This substance is composed of a material which is included in an object and which is the same in type as the object or which can be regarded as being similar to the object in terms of the effective atomic number. Correcting data for replacing the characteristic of the X-ray attenuation amounts ?t by a linear target characteristic are calculated. The linear target characteristic is set to pass through the origin of a two-dimensional coordinate having a lateral axis assigned to thicknesses t and a longitudinal axis assigned to the X-ray attenuation amounts ?t. The correcting data are calculated for each X-ray energy bin.
    Type: Application
    Filed: October 24, 2016
    Publication date: August 2, 2018
    Inventors: Tsutomu YAMAKAWA, Shuichiro YAMAMOTO, Masahiro OKADA
  • Publication number: 20180209922
    Abstract: The type and/or properties of a substance is identified highly accurately regardless of the thickness of the substance. A data processing apparatus processes counts detected at each of pixels of a photo counting detector in each of a plurality of energy ranges of X-rays. The X-rays are radiated from an X-ray tube, and transmitted through an object. The apparatus calculates an image of the object based on the counts, and sets a region of interest on the image. The apparatus further removes, from the pixel, pixel information showing a background present in the region of interest, and calculates, pixel by pixel, inherent information inherent to the substance, based on the counts detected at each of the respective pixels in each of the energy ranges of the X-rays in the region of interest. The inherent information indicates a transmission characteristic inherent to the X-rays.
    Type: Application
    Filed: April 20, 2016
    Publication date: July 26, 2018
    Inventors: Tsutomu YAMAKAWA, Shuichiro YAMAMOTO, Yoshiharu OBATA, Masashi YAMASAKI, Masahiro OKADA
  • Patent number: 10023844
    Abstract: The present invention aims at establishing a novel means for purifying norovirus VLPs. There is provided a purification method of norovirus virus-like particles, comprising: contacting solution containing norovirus virus-like particles with support for hydroxyapatite chromatography, binding the virus-like particles to the support, subsequently washing the support with buffer, and then eluting the virus-like particles from the support with buffer containing phosphate, wherein the phosphate concentration of the buffer used for elution is less than 10 mM.
    Type: Grant
    Filed: May 21, 2014
    Date of Patent: July 17, 2018
    Assignees: UMN PHARMA INC.
    Inventors: Masahiro Okada, Akiko Mukai, Tomonori Nishino, Daisuke Arinobu, Hiroyuki Ito, Mamoru Satoh
  • Patent number: 9642938
    Abstract: In order to provide (i) a medical composition that has a strong angiogenic effect, has low invasiveness to a body of a patient, and is easy to administer to a living subject and (ii) a medical kit using a medical composition, the medical composition includes: a carrier in a particle form, the carrier having (a) a support made from a bioabsorbable polymer and (b) a surface layer made from hydroxyapatite and provided on the support; and cells provided on a surface of the carrier.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: May 9, 2017
    Assignees: OSAKA CITY UNIVERSITY, JAPAN HEALTH SCIENCES FOUNDATION
    Inventors: Shinya Fukumoto, Hidenori Koyama, Yoshiki Nishizawa, Tsutomu Furuzono, Masahiro Okada