Patents by Inventor Masahiro Sokabe

Masahiro Sokabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mammary gland epithelial cell culture
    Patent number: 9290735
    Abstract: To provide a cell culture method capable of sustaining in-vivo functions for a long time by suppressing dedifferentiation. A cell culture method in accordance with the present invention is to culture cells in a multi-layered state in a minute partitioned space and to obtain a tissue structure having a function resembling an in-vivo function. When the cells are mammary gland epithelial cells, a hollow acinus-like structure can be formed. The minute partitioned space is particularly preferably a micro container in a cell culture container having a plurality of such micro containers on the surface.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: March 22, 2016
    Assignees: National University Corporation Nagoya University, KURARAY Co., Ltd.
    Inventors: Masahiro Sokabe, Kishio Furuya, Go Tazaki, Hitoshi Tsuruta, Motohiro Fukuda
  • CELL CULTURE METHOD
    Publication number: 20100331216
    Abstract: To provide a cell culture method capable of sustaining in-vivo functions for a long time by suppressing dedifferentiation. A cell culture method in accordance with the present invention is to culture cells in a multi-layered state in a minute partitioned space and to obtain a tissue structure having a function resembling an in-vivo function. When the cells are mammary gland epithelial cells, a hollow acinus-like structure can be formed. The minute partitioned space is particularly preferably a micro container in a cell culture container having a plurality of such micro containers on the surface.
    Type: Application
    Filed: February 5, 2009
    Publication date: December 30, 2010
    Applicants: National University Corporation Nagoya University, Kuraray Co., Ltd.
    Inventors: Masahiro Sokabe, Kishio Furuya, Go Tazaki, Hitoshi Tsuruta, Motohiro Fukuda
  • Low-molecular weight peptides inhibiting ion channel activity
    Publication number: 20090181899
    Abstract: It is intended to provide novel polypeptides which specifically inhibit the activity of a mechano-sensitive channel; and mechano-sensitive channel inhibitors or remedies for atrial fibrillation containing these polypeptides or salts thereof. The above objects can be achieved by using polypeptides having amino acid sequences represented by SEQ ID NO: 1 (TVP003), SEQ ID NO:2 (TVP004) and SEQ ID NO:3 (TVP005), salts of these polypeptides, and mechano-sensitive channel inhibitors or remedies for atrial fibrillation containing the same.
    Type: Application
    Filed: May 28, 2008
    Publication date: July 16, 2009
    Applicant: PHARMADESIGN, INC.
    Inventors: Takane Yokotagawa, Masahiro Sokabe, Toshio Furuya
  • Low-molecular weight peptides inhibiting ion channel activity
    Patent number: 7396816
    Abstract: It is intended to provide novel polypeptides which specifically inhibit the activity of a mechano-sensitive channel; and mechano-sensitive channel inhibitors or remedies for atrial fibrillation containing these polypeptides or salts thereof. The above objects can be achieved by using polypeptides having amino acid sequences represented by SEQ ID NO:1 (TVP003), SEQ ID NO:2 (TVP004) and SEQ ID NO:3 (TVP005), salts of these polypeptides, and mechano-sensitive channel inhibitors or remedies for atrial fibrillation containing the same.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: July 8, 2008
    Assignee: Pharmadesign, Inc.
    Inventors: Takane Yokotagawa, Masahiro Sokabe, Toshio Furuya
  • Low-molecular weight peptides inhibiting ion channel activity
    Publication number: 20060229434
    Abstract: It is intended to provide novel polypeptides which specifically inhibit the activity of a mechano-sensitive channel; and mechano-sensitive channel inhibitors or remedies for atrial fibrillation containing these polypeptides or salts thereof. The above objects can be achieved by using polypeptides having amino acid sequences represented by SEQ ID NO:I (TVPOO3), SEQ ID NO:2 (TVPOO4) and SEQ ID NO:3 (TVPOO5), salts of these polypeptides, and mechano-sensitive channel inhibitors or remedies for atrial fibrillation containing the same.
    Type: Application
    Filed: March 25, 2004
    Publication date: October 12, 2006
    Inventors: Takane Yokotagawa, Masahiro Sokabe, Toshio Furuya