Patents by Inventor Masakatsu Hasegawa

Masakatsu Hasegawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8455616
    Abstract: The present invention provides a peptide comprising amino acid sequences R I, F I and R I G C and containing 25 or fewer amino acid residues, and capable of transporting a functional molecule into a cell, and also into a nucleus, more efficiently than a previous PTD.
    Type: Grant
    Filed: March 6, 2008
    Date of Patent: June 4, 2013
    Assignee: National Center for Global Health and Medicine
    Inventors: Yukihito Ishizaka, Masakatsu Hasegawa, Satoshi Nohara
  • Publication number: 20100203611
    Abstract: The present invention provides a peptide comprising amino acid sequences R I, F I and R I G C and containing 25 or fewer amino acid residues, and capable of transporting a functional molecule into a cell, and also into a nucleus, more efficiently than a previous PTD.
    Type: Application
    Filed: March 6, 2008
    Publication date: August 12, 2010
    Inventors: Yukihito Ishizaka, Masakatsu Hasegawa, Satoshi Nohara
  • Patent number: 7678777
    Abstract: A composition for promoting bacterial proliferation and selectively proliferating Lactobacillus casei subsp. casei is disclosed, which includes a dextran. A variety of biological activities originating from L. casei subsp. casei can be sustained in a living body by selectively growing-proliferating and colonizing L. casei subsp. casei in the intestine of a human being, animal, or the like or by selectively growing-proliferating L. casei subsp. casei in the intestine, without supplying L. casei subsp. casei at all times.
    Type: Grant
    Filed: August 12, 2008
    Date of Patent: March 16, 2010
    Assignee: Meito Sangyo Co., Ltd.
    Inventors: Kenji Yasuda, Tomohiko Ogawa, Masakatsu Hasegawa
  • Publication number: 20080305090
    Abstract: A composition for promoting bacterial proliferation and selectively proliferating Lactobacillus casei subsp. casei is disclosed, which includes a dextran. A variety of biological activities originating from L. casei subsp. casei can be sustained in a living body by selectively growing-proliferating and colonizing L. casei subsp. casei in the intestine of a human being, animal, or the like or by selectively growing-proliferating L. casei subsp. casei in the intestine, without supplying L. casei subsp. casei at all times.
    Type: Application
    Filed: August 12, 2008
    Publication date: December 11, 2008
    Applicant: Meito Sangyo Co., Ltd.
    Inventors: Kenji Yasuda, Tomohiko Ogawa, Masakatsu Hasegawa
  • Publication number: 20060127378
    Abstract: The present invention relates to a composition for promoting bacterial proliferation for selectively proliferating Lactobacillus casei subsp. casei, which includes a dextran. According to the present invention, a variety of biological activities originated from L. casei subsp. casei can be sustained in a living body by selectively growing-proliferating and colonizing L. casei subsp. casei in the intestine of a human being, animal, or the like or by selectively growing-proliferating L. casei subsp. casei in the intestine, without supplying L. casei subsp. casei at all times.
    Type: Application
    Filed: July 22, 2003
    Publication date: June 15, 2006
    Inventors: Kenji Yasuda, Tomohiko Ogawa, Masakatsu Hasegawa
  • Patent number: 6165378
    Abstract: The present invention provides a polysaccharide-magnetic metal oxide complex consisting of a polysaccharide derivative obtained by carboxyalkyl-etherifying and unsubstituted or substituted aminoalkyl-etherifying a polysaccharide (the above carboxy group and/or amino group may be of a salt form) and a magnetic metal oxide. The above complex has a slow blood clearance and a low toxicity and is useful as a nuclear magnetic resonance imaging contrast medium.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: December 26, 2000
    Assignee: Meito Sangyo Kabushiki Kaisha
    Inventors: Shigeo Maruno, Masakatsu Hasegawa, Takamasa Hanaichi, Katsutoshi Murase, Hisato Yamada, Hideo Nagae, Kyoji Kito
  • Patent number: 5766572
    Abstract: A water-soluble carboxypolysaccharide-magnetic iron oxide complex of small particle diameter composed of a water-soluble carboxypolysaccharide and a magnetic iron oxide having a core diameter ranging from about 2 to about 7 nm, wherein the total diameter ranges from about 10 to about 50 nm, the ratio of the total diameter to the core diameter is about 15 or less, and the T.sub.2 -relaxivity ranges from about 10 to about 150 (mM.sec).sup.-1. Said complex has low toxicity and small side effects and is useful in the fields of medical treatment, biology and engineering as an iron-supplementing agent, an X-ray contrast medium, an MRI contrast medium, a reagent for blood flow rate measurement, a carrier for drug administration, etc.
    Type: Grant
    Filed: February 6, 1995
    Date of Patent: June 16, 1998
    Assignee: Meito Sangyo Kabushiki Kaisha
    Inventors: Masakatsu Hasegawa, Yoshio Ito, Hisato Yamada, Hideo Nagae, Nahoko Tozawa, Yukari Hino, Kyoji Kito, Shusaburo Hokukoku, Rudiger Lawaczeck, Wolfgang Ebert, Detlef Pfefferer, Susanne Wagner, Mayk Kresse
  • Patent number: 5592849
    Abstract: A yarn unevenness information analyzing apparatus which can perform an analysis of periodic yarn unevennesses without being restricted by another analysis of non-periodic yarn unevennesses. Signals from a large number of yarn evenness detectors are inputted to a CPU for yarn unevenness analysis by way of a first switch for changing over the signals in a short period to successively output the signals and a second switch for changing over the signals in a long period to successively output the signals.
    Type: Grant
    Filed: November 13, 1995
    Date of Patent: January 14, 1997
    Assignee: Murata Kikai Kabushiki Kaisha
    Inventors: Kazuhiko Nakade, Shujiro Suzuki, Masakatsu Hasegawa
  • Patent number: 5424419
    Abstract: An oxidized complex comprising a water-soluble carboxypolysaccharide and magnetic iron oxide, which is characterized by being obtained by oxidizing a complex comprising a water-soluble carboxypolysaccharide and magnetic iron oxide. Said oxidized complex has very low toxicity, is very stable, exhibits little or no blood pressure-reducing action and has low platelets-aggregating action when administered directly into the blood vessels of animals, and is useful in medical fields such as contrast medium for magnetic resonance imaging, exothermic medium for hyperthermia and the like.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: June 13, 1995
    Assignee: Meito Sangyo Kabushiki Kaisha
    Inventors: Masakatsu Hasegawa, Hideo Nagae, Yoshio Ito, Akihiro Mizutani, Kimio Hirose, Masahiro Ohgai, Yasuji Yamashita, Nahoko Tozawa, Keiko Yamada, Kyoji Kito, Shusaburo Hokukoku
  • Patent number: 5328681
    Abstract: A composition containing magnetic metal oxide ultrafine particles, which comprises an aqueous sol of a complex of the magnetic metal oxide ultrafine particles with a polysaccharide, a polysaccharide derivative and/or a protein; and an organic monocarboxylic acid. The composition is free of side effects such as platelet aggregation, is safe for use with living bodies, and, in the case of intravascular administration, has no harmful effects on living bodies, and is useful in fields such as medicine and diagnostic drugs.
    Type: Grant
    Filed: September 17, 1992
    Date of Patent: July 12, 1994
    Assignee: Meito Sangyo Kabushiki Kaisha
    Inventors: Kyoji Kito, Hideo Nagae, Masakatsu Hasegawa, Yoshio Ito, Akihiro Mizutani, Kimio Hirose, Yasuji Yamashita, Nahoko Tozawa, Keiko Yamada, Masahiro Ohgai, Shusaburo Hokukoku
  • Patent number: 5204457
    Abstract: A complex of a carboxyalkyl ether of a polysaccharide with a magnetic metal oxide. This complex is extremely excellent in stability in preservation in the form of aqueous sol and has only a low toxicity, and thus is useful, for example, for medical use as a nuclear magnetic imaging molding agent or the like.
    Type: Grant
    Filed: June 20, 1991
    Date of Patent: April 20, 1993
    Assignees: Meito Sangyo Kabushiki Kaisha, Shigeo Maruno
    Inventors: Shigeo Maruno, Masakatsu Hasegawa
  • Patent number: 4101435
    Abstract: A magnetic iron oxide-dextran complex. This novel compound can be produced by reacting an aqueous sol of magnetic iron oxide with dextran having an intrinsic viscosity of about 0.02 to about 0.5 at an elevated temperature in an aqueous medium, and is useful not only in pharmaceutical and medical fields as a hematinic medium, a radiopaque medium, a blood measuring agent, or a carrier for a medicinal substance, but also in wide range of other technological fields where its magnetic property can be utilized.
    Type: Grant
    Filed: June 14, 1976
    Date of Patent: July 18, 1978
    Assignee: Meito Sangyo Kabushiki Kaisha
    Inventors: Masakatsu Hasegawa, Syusaburo Hokkoku