Patents by Inventor Masakatsu Shibasaki

Masakatsu Shibasaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10974232
    Abstract: A catalyst represented by General Formula (1) below: where in the General Formula (1), R1 to R14 each independently represent a hydrogen atom or a substituent.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: April 13, 2021
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Naoya Kumagai, Christopher Roderick Opie, Hidetoshi Noda, Masakatsu Shibasaki
  • Publication number: 20200206724
    Abstract: A catalyst represented by General Formula (1) below: where in the General Formula (1), R1 to R14 each independently represent a hydrogen atom or a substituent.
    Type: Application
    Filed: August 14, 2018
    Publication date: July 2, 2020
    Inventors: Naoya Kumagai, Christopher Roderick Opie, Hidetoshi Noda, Masakatsu Shibasaki
  • Patent number: 10413892
    Abstract: A catalyst including: neodymium; sodium; and a ligand, which is a compound expressed by Structural Formula (1) below, wherein the neodymium and the ligand form a complex at a molar ratio of 1:2 (neodymium:ligand):
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: September 17, 2019
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Masakatsu Shibasaki, Naoya Kumagai, Akihito Nonoyama, Kazuki Hashimoto, Akira Saito
  • Publication number: 20180345260
    Abstract: A catalyst including: neodymium; sodium; and a ligand, which is a compound expressed by Structural Formula (1) below, wherein the neodymium and the ligand form a complex at a molar ratio of 1:2 (neodymium:ligand):
    Type: Application
    Filed: November 21, 2016
    Publication date: December 6, 2018
    Inventors: Masakatsu SHIBASAKI, Naoya KUMAGAI, Akihito NONOYAMA, Kazuki HASHIMOTO, Akira SAITO
  • Patent number: 9951067
    Abstract: A method for producing an optically active ?-trifluoromethyl-?-amino acid derivative, the method including: allowing a compound represented by the following General Formula (1) and a compound represented by the following General Formula (2) to react in the presence of a copper-optically active phosphine complex obtained from a copper compound and an optically active phosphine compound, to thereby obtain an optically active ?-trifluoromethyl-?-amino acid derivative represented by the following General Formula (3):
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: April 24, 2018
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Masakatsu Shibasaki, Naoya Kumagai, Liang Yin
  • Patent number: 9901913
    Abstract: A catalyst, which is obtained by mixing a compound expressed by the following Structural Formula (1), a nitroalkane compound, a neodymium-containing compound, a sodium-containing compound, and a carbon structure:
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: February 27, 2018
    Assignee: MICROBIAL CHEMISTRY RESEARCH FOUNDATION
    Inventors: Masakatsu Shibasaki, Naoya Kumagai, Takanori Ogawa
  • Publication number: 20170283411
    Abstract: A method for producing an optically active ?-trifluoromethyl-?-amino acid derivative, the method including: allowing a compound represented by the following General Formula (1) and a compound represented by the following General Formula (2) to react in the presence of a copper-optically active phosphine complex obtained from a copper compound and an optically active phosphine compound, to thereby obtain an optically active ?-trifluoromethyl-?-amino acid derivative represented by the following General Formula (3):
    Type: Application
    Filed: September 18, 2015
    Publication date: October 5, 2017
    Applicant: MICROBIAL CHEMISTRY RESEARCH FOUNDATION
    Inventors: Masakatsu SHIBASAKI, Naoya KUMAGAI, Liang YIN
  • Patent number: 9493492
    Abstract: A method for producing a compound represented by General Formula (1), the method including: reacting a compound represented by General Formula (3) and a compound represented by General Formula (4): where R1 and R2 each represent aliphatic group which may have substituent, or aromatic group which may have substituent (with the proviso that R1 and R2 are different groups), R3 represents aromatic group which may have substituent, and R4 represents aliphatic group which may have substituent, or aromatic group which may have substituent, where R1 and R2 each represent aliphatic group which may have substituent, or aromatic group which may have substituent (with the proviso that R1 and R2 are different groups), and R3 represents aromatic group which may have substituent, where R4 represents aliphatic group which may have substituent, or aromatic group which may have substituent.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: November 15, 2016
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Masakatsu Shibasaki, Naoya Kumagai, Liang Yin, Youmei Bao
  • Publication number: 20160145278
    Abstract: A method for producing a compound represented by General Formula (1), the method including: reacting a compound represented by General Formula (3) and a compound represented by General Formula (4): where R1 and R2 each represent aliphatic group which may have substituent, or aromatic group which may have substituent (with the proviso that R1 and R2 are different groups), R3 represents aromatic group which may have substituent, and R4 represents aliphatic group which may have substituent, or aromatic group which may have substituent, where R1 and R2 each represent aliphatic group which may have substituent, or aromatic group which may have substituent (with the proviso that R1 and R2 are different groups), and R3 represents aromatic group which may have substituent, where R4 represents aliphatic group which may have substituent, or aromatic group which may have substituent.
    Type: Application
    Filed: October 8, 2013
    Publication date: May 26, 2016
    Inventors: Masakatsu SHIBASAKI, Naoya KUMAGAI, Liang YIN, Youmei BAO
  • Publication number: 20150375219
    Abstract: A catalyst, which is obtained by mixing a compound expressed by the following Structural Formula (1), a nitroalkane compound, a neodymium-containing compound, a sodium-containing compound, and a carbon structure:
    Type: Application
    Filed: February 7, 2014
    Publication date: December 31, 2015
    Applicant: Microbial Chemistry Rsearch Fiundation
    Inventors: Masakatsu SHIBASAKI, Naoya KUMAGAI, Takanori OGAWA
  • Patent number: 9187498
    Abstract: A compound represented by the following General Formula (1): where R1 represents a protective group for a hydroxyl group or a hydrogen atom, and R2 represents a methyl group or an ethyl group.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: November 17, 2015
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Masakatsu Shibasaki, Naoya Kumagai
  • Publication number: 20150183807
    Abstract: A compound represented by the following General Formula (1): where R1 represents a protective group for a hydroxyl group or a hydrogen atom, and R2 represents a methyl group or an ethyl group.
    Type: Application
    Filed: March 16, 2015
    Publication date: July 2, 2015
    Inventors: Masakatsu SHIBASAKI, Naoya KUMAGAI
  • Patent number: 8981123
    Abstract: A compound represented by the following General Formula (1): where R1 represents a protective group for a hydroxyl group or a hydrogen atom, and R2 represents a methyl group or an ethyl group.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: March 17, 2015
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Masakatsu Shibasaki, Naoya Kumagai
  • Patent number: 8940919
    Abstract: A compound represented by the following general formula (1), and a method for producing the compound represented by the general formula (1), the method comprising: reacting together a compound represented by the following general formula (2), a compound represented by the following general formula (3), and a compound represented by the following general formula (4): wherein R1 represents any of a protective group of a carboxyl group, and a hydrogen atom, R2 and R3 each independently represent any of a protective group of an amino group, and a hydrogen atom, and R4 represents any of a protective group of a carboxyl group, and a hydrogen atom.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: January 27, 2015
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Masakatsu Shibasaki, Kenzo Yamatsugu
  • Publication number: 20140296539
    Abstract: A compound represented by the following General Formula (1): where R1 represents a protective group for a hydroxyl group or a hydrogen atom, and R2 represents a methyl group or an ethyl group.
    Type: Application
    Filed: June 11, 2014
    Publication date: October 2, 2014
    Inventors: Masakatsu SHIBASAKI, Naoya KUMAGAI
  • Patent number: 8785690
    Abstract: A thioamide compound represented by the following general formula (1): wherein, in the general formula (1), R1 represents one of —OR11 and —NR12R13; R2 and R3 each independently represent one of a protecting group of an amide group and a hydrogen atom; the R11 represents one of a protecting group of a hydroxyl group and a hydrogen atom; and the R12 and R13 each independently represent one of a protecting group of an amino group and a hydrogen atom, where the R12 and R13 may together form a protecting group having a cyclic structure.
    Type: Grant
    Filed: August 20, 2013
    Date of Patent: July 22, 2014
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Masakatsu Shibasaki, Naoya Kumagai
  • Publication number: 20140046087
    Abstract: A compound represented by the following general formula (1), and a method for producing the compound represented by the general formula (1), the method comprising: reacting together a compound represented by the following general formula (2), a compound represented by the following general formula (3), and a compound represented by the following general formula (4): wherein R1 represents any of a protective group of a carboxyl group, and a hydrogen atom, R2 and R3 each independently represent any of a protective group of an amino group, and a hydrogen atom, and R4 represents any of a protective group of a carboxyl group, and a hydrogen atom.
    Type: Application
    Filed: September 4, 2013
    Publication date: February 13, 2014
    Applicant: Microbial Chemistry Research Foundation
    Inventors: Masakatsu SHIBASAKI, Kenzo YAMATSUGU
  • Publication number: 20130338375
    Abstract: A thioamide compound represented by the following general formula (1); wherein, in the general formula (1), R1 represents one of —OR11 and —NR12R13; R2 and R3 each independently represent one of a protecting group of an amide group and a hydrogen atom; the R11 represents one of a protecting group of a hydroxyl group and a hydrogen atom; and the R12 and R13 each independently represent one of a protecting group of an amino group and a hydrogen atom, where the R12 and R13 may together form a protecting group having a cyclic structure.
    Type: Application
    Filed: August 20, 2013
    Publication date: December 19, 2013
    Applicant: Microbial Chemistry Research Foundation
    Inventors: Masakatsu SHIBASAKI, Naoya KUMAGAI
  • Publication number: 20100298559
    Abstract: There is provided a novel optically active dinickel complex and/or a production method of an optically active amine by an asymmetric Mannich reaction using the dinickel complex as a catalyst. An optically active dinickel complex of Formula (I) or Formula (I?): [where R0, R1, R2, R3, R4, R5, R6, and R7 are each independently a hydrogen atom, a halogen atom, a C1-10 alkyl group or a C1-10 alkoxy group, etc., R2 and R3 together form, together with a benzene ring bonded to them, a naphthalene ring, etc. A novel production method of an optically active amine by an asymmetric Mannich reaction using the dinickel complex as a catalyst.
    Type: Application
    Filed: December 10, 2008
    Publication date: November 25, 2010
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Masakatsu Shibasaki, Shigeki Matsunaga, Zhihua Chen
  • Patent number: 7820862
    Abstract: Disclosed is a novel asymmetric ligand which can be synthesized by a short process at low cost and is capable of exhibiting higher catalytic activity and enantioselectivity than the conventional ligands derived from sugars. Also disclosed are a method for producing such an asymmetric ligand, and a catalyst using such an asymmetric ligand. Specifically disclosed is a ligand represented by the general formula I below or the like. (In the formula, R1 and R2 independently represent 0-5 substituents; X represents P, As or N; m represents an integer of 0-7; n represents an integer of 0-3; A1-A4 independently represent hydrogen, fluorine, chlorine, bromine, benzoyl or acetyl, or alternatively A2 and A3 combine together to form a ring.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: October 26, 2010
    Assignee: The University of Tokyo
    Inventors: Masakatsu Shibasaki, Motomu Kanai, Ikuo Fujimori, Kenzo Yamatsugu, Shin Kamijo