Abstract: A particle imaging apparatus comprises a flow path comprising a first flow path section, a second flow path section connected downstream of the first flow path section, and a third flow path section that is branched from the first flow path section, a particle detection unit comprising a light source and a light detector, a particle sorting unit configured to adjust a flow direction of the particle, and a particle imaging unit configured to take an image of a particle that flows in the second flow path section. The flow path is structured such that a cross-sectional area of the second flow path section is greater than a cross-sectional area of the first flow path section. The first flow path section and the second flow path section are disposed so as to be linearly aligned.

Abstract: A cell analyzing method includes measuring cells that are nuclear stained, by a cytometric device, to obtain a histogram of a parameter of a fluorescence signal, where the parameter indicates an amount of DNA in a nucleus of a cell. A number of cells that are distributed in an area where the parameter of the fluorescence signal is larger than normal cells are obtained by a computer having at least one processor. The possibility of cancer is determined based on the obtained number of cells and the histogram.

Abstract: A cell analysis apparatus includes an optical detection section that accommodates a flow of a measurement sample obtained from a biological sample and a pigment into a flow cell. A light source irradiates the measurement sample flowing in the flow cell and a fluorescence detector detects fluorescence from the measurement sample. A signal processing circuit acquires a value reflecting the height of a waveform of the signal and a value reflecting the length of a ridge line of the waveform of the signal, and a system control section distinguishes between an aggregating cell formed by aggregation of a plurality of cells and a non-aggregating cell, based on the value of the fluorescence signal obtained by the signal processing circuit.

Abstract: A particle imaging apparatus comprises a flow path comprising a first flow path section, a second flow path section connected downstream of the first flow path section, and a third flow path section that is branched from the first flow path section, a particle detection unit comprising a light source and a light detector, a particle sorting unit configured to adjust a flow direction of the particle, and a particle imaging unit configured to take an image of a particle that flows in the second flow path section. The flow path is structured such that a cross-sectional area of the second flow path section is greater than a cross-sectional area of the first flow path section. The first flow path section and the second flow path section are disposed so as to be linearly aligned.

Abstract: A cell analysis apparatus that can accurately distinguish between an aggregating cell and a non-aggregating cell is provided.

Abstract: A cell analysis apparatus that can accurately distinguish between an aggregating cell and a non-aggregating cell is provided.

Abstract: A sample preparation apparatus comprising: a detector for detecting a predetermined cell included in a biological sample; a sample preparation section for preparing a measurement sample from the biological sample and a predetermined reagent; and a controller configured to generate, based on a detection result by the detector, concentration information reflecting a concentration of the predetermined cell in the biological sample and to control, based on the concentration information, the amount of the biological sample supplied to the sample preparation section.

Abstract: A cell analyzing apparatus, comprising: a parameter obtaining section for obtaining a characteristic parameter from a cell in a measurement sample; an imaging section for capturing an image of the cell in the measurement sample; an analyzing section for counting a cell in which the characteristic parameter meets a predetermined requirement among the cells in the measurement sample as a counting target and generating output data based on a counting result; a display section for displaying an image of the cell meeting the predetermined requirement and the output data; and an input section for receiving an instruction to specify the image displayed on the display section, wherein the analyzing section excludes a cell relevant to the specified image from the counting target and regenerates the output data is disclosed. A cell analyzing method is also disclosed.

Abstract: A sample preparation apparatus comprising: a detector for detecting a predetermined cell included in a biological sample; a sample preparation section for preparing a measurement sample from the biological sample and a predetermined reagent; and a controller configured to generate, based on a detection result by the detector, concentration information reflecting a concentration of the predetermined cell in the biological sample and to control, based on the concentration information, the amount of the biological sample supplied to the sample preparation section.

Abstract: The present invention is to present a cell analyzer capable of measuring cells which are approximately 20 to 100 ?m in size with high precision via flow cytometry. The cell analyzer 10 comprises: a flow cell 51 in which a measurement sample including a measurement target cell flows; a light source part 53 for irradiating a light on the measurement sample flowing in the flow cell 51; an optical system 52 for forming a beam spot on the measurement sample flowing in the flow cell 51, the beam spot having a diameter of 3˜8 ?m in a flow direction of the measurement sample and a diameter of 300˜600 ?m in a direction perpendicular to the flow direction of the measurement sample; and a light receiving part 55, 58, 59 for receiving a light from the measurement sample.

Abstract: A cell analysis apparatus that can accurately distinguish between an aggregating cell and a non-aggregating cell is provided.

Abstract: The present invention is to present a cell analyzer capable of measuring cells which are approximately 20 to 100 ?m in size with high precision via flow cytometry. The cell analyzer 10 comprises: a flow cell 51 in which a measurement sample including a measurement target cell flows; a light source part 53 for irradiating a light on the measurement sample flowing in the flow cell 51; an optical system 52 for forming a beam spot on the measurement sample flowing in the flow cell 51, the beam spot having a diameter of 3˜8 ?m in a flow direction of the measurement sample and a diameter of 300˜600 ?m in a direction perpendicular to the flow direction of the measurement sample; and a light receiving part 55, 58, 59 for receiving a light from the measurement sample.

Abstract: Highly accurate and easy discrimination of cancer/atypical cells is achieved. A cancer/atypical cell discrimination method comprises: measuring a plurality of cells by a flow cytometer; acquiring a scattered light signal for each of the cells; calculating at least one characteristic parameter by analyzing the waveform of the scattered light signal; and discriminating a cancer/atypical cell from the plurality of cells based on the characteristic parameter.

Abstract: A cell processing method for processing and collecting cells in a cell suspension fluid with reagent comprising: filtering a cell suspension fluid using a membrane filter; processing the cells ion the membrane filter with reagent; supplying a collection fluid to produce a shearing force that acts on the cells processed with reagent so as to separate the cells on the membrane filter into the collection fluid; and recovering the collection fluid that retains the cells separated from the membrane filter.

Abstract: The invention provides a reagent for diagnosing cervical cancer, which can not only detect the presence or absence of cervical cancer but can also distinguish squamous cell carcinoma and adenocarcinoma from each other, a method for screening cervical cancer by using the reagent, particularly a screening method capable high speed processing by utilizing flow cytometry. The reagent comprises a first labeled antibody reacting with gland cells, a second labeled antibody reacting with adenocarcinoma cells and a third labeled antibody reacting with atypical cervical squamous cells, the antibodies being labeled with mutually distinguishable labels respectively.

Abstract: An optical information measuring apparatus includes: a light source section capable of emitting a plurality of light beams; a light guiding section for directing and supplying the plurality of light beams from the light source section to an object; an object lens arranged facing the object; a plurality of light receiving sections for respectively receiving the light beams from the object via the object lens; and a frame section for integrally mounting a plurality of optical elements including the light source section, the light guiding section, the object lens, and the light-receiving sections.

Abstract: The boundary of an object is determined based on its optically captured image by: (a) converting a density data of each of a plurality of pixels forming the captured image into a binary signal; (b) converting the binary signal into a neighbor pixel state value so that only the pixels located on the boundary r in the interior of the object have a value corresponding to the binary signals of the surrounding pixels; (c) normalizing the neighbor pixel state value using an absolute chain direction value of a previous chain direction; (d) obtaining a relative chain direction value for a pixel located on the boundary of the object in the image relative to the direction from which the chain has proceeded, with reference to the neighbor pixel state value of the pixel; (e) calculating an absolute chain direction value of a next chain direction on the basis of the relative chain direction value; and (f) repeating the steps (c) to (e) for each pixel located on the boundary to trace the boundary of the object for determin

Abstract: A multiple light source unit includes a plurality of light sources for emitting light beams. There is a condensing lens and the light beams are parallel to an optical axis of the condensing lens. Included is a mirror for directing the light beams from the plurality of light sources to the condensing lens. A light guiding element for receiving the condensed light beams through a light receiving section and for emitting the light beams through a light emitting section is also provided. The light beams from the plurality of light sources are incident, through respective positions on the condensing lens, into the light receiving section of the light guiding element.