Abstract: A method of examining for cancer in a non-primate mammal such as a pet animal may include, for example, a method of examining or diagnosing for cancer in a non-primate mammal, including evaluating taxic behavior of nematodes toward a urine sample from a subject mammal.

Abstract: To provide a vehicle that includes a balancer mechanism for reducing vibration of the engine and can leave a space margin for increasing the fuel tank in size and/or arranging equipment or components at the rear of the cylinder and above the crankcase. A vehicle includes: an engine mounted on a body frame. The engine comprises a crankcase with a ceiling wall, a crankshaft provided in the crankcase, and a balancer mechanism for reducing vibration of the engine by power transmitted from the crankshaft. The balancer mechanism comprises an idler gear disposed behind the crankshaft and rotated by power transmitted from the crankshaft, and a first balancer disposed behind the idler gear and rotated by power transmitted from the idler gear. The idler gear and the first balancer are disposed along the ceiling wall.

Abstract: A flush toilet includes: a toilet main unit having a bowl portion, and a water conduit formed in the toilet main unit and configured to supply flush water into the bowl portion. The water conduit has: a first water-guiding portion extending from a water supply portion to a first spout port located on one of right and left sides of the bowl portion; and a second water-guiding portion extending from the water supply portion to a second spout port located on the other of the right and left sides of the bowl portion. The water supply portion is located at a right-sided or left-sided position in a right and left direction. The flush water is supplied to the water supply portion in a direction inclined with respect to a front and back direction and intersected with an inside surface of the water supply portion, as seen in plan view.

Abstract: The purpose of the present invention is to provide a nucleic acid medication for cancer treatment, the medication being capable of suppressing the growth of cancer stem cells and thus effectively treating cancer. hsa-miR-136-5p, hsa-miR-3065-3p, hsa-miR-4727-5p, hsa-miR-378g, hsa-miR-181a-5p, hsa-miR-362-5p, and hsa-miR-608 have remarkably excellent growth inhibitory action on cancer stem cells and are thus useful as a nucleic acid medication for the treatment of various cancers.

Abstract: An object to be achieved by the present invention is to provide a technique for enhancing the anticancer effect of ubenimex; in particular, enhancing its anticancer effect on solid cancer. This object can be achieved by a compound containing a chain structure in which a plurality of ubenimex molecules is linked to a chain polymer.

Abstract: The water conduit has: a first water-guiding portion extending from a water supply portion, where the flush water is supplied to the water conduit, to a first spout port located on one of right and left sides of the bowl portion; and a second water-guiding portion extending from the water supply portion to a second spout port located on the other side. The water supply portion is located at a position on the one side. The flush water is supplied to the water supply portion in a direction from the water supply portion toward the first water-guiding portion. A collision wall is provided on a way of the first water-guiding portion such that at least a part of the supplied flush water collides with the collision wall. The at least part of the flush water having collided with the collision wall is supplied to the second water-guiding portion.

Abstract: A lubrication mechanism for supplying oil to a bearing of a vehicle electric motor that includes the bearing, a housing, a stator and a rotor having a rotor shaft rotatably held by the housing through the bearing. The housing defines an oil passage to which oil discharged from an oil pump is to be supplied. The oil passage and the bearing are located on respective opposite sides of a wall of the housing. The lubrication mechanism includes: a bolt hole passing through the wall; and a bolt engaged in the bolt hole.

Abstract: A vehicle electric motor including: a tubular-shaped stator core constituted by laminated steel sheets; a casing including an outer circumferential wall and a bottom wall, and storing therein an axial end portion of the stator core; a casing cover including an outer circumferential wall and a bottom wall, and storing therein another axial end portion of the stator core, and a rotor disposed inside the stator core. The stator core includes fastened portions protruding radially outwardly from respective portions of an outer circumferential surface of the stator core which are circumferentially spaced apart from each other. The stator core is fastened at the fastened portions to the bottom wall of one of the casing and the casing cover. The other of the casing and the casing cover includes protrusion portions protruding from its inner wall surface toward the stator core so as to restrain inclination of the stator core.

Abstract: The present invention provides a specific combination of colon cancer markers based on statistical knowledge, which is capable of detecting a larger number of colon cancer patients in an earlier stage while maintaining high specificity. A multiplex colon cancer marker panel comprising a combination of five colon cancer markers of Carcinoembryonic antigen-related cell adhesion molecule 5, Carbohydrate antigen 19-9, Galectin-4, APEX nuclease and Actin-related protein 2. A method for analyzing colon cancer markers using multiplex colon cancer marker panel.

Abstract: A method for forming a sealing film, in which a buffer layer and a barrier layer whose density is higher than that of the buffer layer are alternately formed on a substrate, includes forming a first buffer layer on a surface of the substrate, forming a first barrier layer on a surface of the first buffer layer, and forming a second buffer layer on a surface of the first barrier layer. A ratio of a thickness of a portion of the first buffer layer in a thickness direction of the substrate relative to a thickness of a portion of the first buffer layer in an inclined direction that is inclined with respect to the thickness direction is closer to 1 than a ratio of a thickness of a portion of the second buffer layer in the thickness direction relative to a thickness of a portion of the second buffer layer in the inclined direction.

Abstract: The terminal portion extends onto a surface of the protrusion portion from part positioned in the second layer and corresponding to the second portion, and part on the surface of the protrusion portion contacts an electrode of the drive element.

Abstract: A flush toilet includes a toilet main body, a flush water tank device, and connection conduits for supplying, to a toilet main body, flush water supplied from a reservoir tank. The reservoir tank includes a large tank portion on a large volume side in the reservoir tank when the reservoir tank is divided into two at the left-right center and a small tank portion on a small volume side in the reservoir tank when the reservoir tank is divided into two at the left-right center. The upstream end of one connection conduit is connected to the large tank portion and, on the other hand, the downstream end of the other connection conduit is connected to the other side of the toilet main body divided into two at the left-right center.

Abstract: A wireless power-feeding apparatus that enables efficient wireless feeding to a power-receiving coil embedded at the center of a spherical power-receiving device. The apparatus includes: a holding member for holding the power-receiving device; a power-transmitting coil; a driver circuit for supplying the power-transmitting coil with high-frequency current to generate a magnetic flux for wireless power-feeding to the power-receiving coil; and a wireless data receiver for receiving data transmitted regularly from a wireless data transmitter, the power-transmitting coil being positioned relative to the holding member in such a manner that the axes of the power-receiving coil and the power-transmitting coil are parallel to each other when the power-receiving device is held by the holding member in such a manner that a mark provided on the surface of the power-receiving device faces a predetermined direction.

Abstract: A rotating machine lubrication structure is applied to a rotating machine including a cylindrical stator, a rotor and a shaft. A resolver is disposed concentrically with the rotating machine center line between the bearing and the rotor in a direction of the rotating machine center line in the casing, the resolver includes an annular resolver stator fixed to an inner side surface of the casing in an outer circumferential portion of the resolver stator, and a resolver rotor disposed on an inner circumferential side of the resolver stator and fixed to and integrally rotated with the shaft, and the resolver stator is provided with an oil through-hole allowing the lubricating oil to flow through at a portion on an inner circumferential side relative to a part fixed to the casing.

Abstract: The purpose of the present invention is to provide a therapeutic agent which is for inflammatory bowel disease and exhibits superior prophylactic or therapeutic effects on inflammatory bowel disease by using miR-29a and/or miR-29h. The prophylactic or therapeutic agent for inflammatory bowel disease comprises composite particles in which miR-29a and/or miR-29b is/are carried on carbonate apatite particles, and said agent is administered systemically.

Abstract: A bearing unit structure includes a bearing and a bearing holding unit. The bearing rotatably supports a drive shaft. The bearing holding unit is provided to a crankcase so as to hold the bearing. A groove portion is formed on an inner peripheral surface ? of the bearing holding unit, and the inner peripheral surface ? faces the bearing. A thermal expansion correction band made of a resin is integrally formed with the bearing holding unit in a state of being embedded into the groove portion.

Abstract: A vehicle electric motor including: a tubular-shaped stator core constituted by electromagnetic steel sheets that are laminated on each other; a rotor disposed inside the stator core so as to be rotated about an axis; and a housing storing therein the tubular-shaped stator core and the rotor, and including a circumferential wall and axially opposite end walls that are opposed to each other in a direction parallel with the axis. The stator core is fixed at one of its axially end portions to one of the axially opposite end walls of the housing. The housing includes a stator-core-inclination restraining portion that protrudes from an inner circumferential surface of the circumferential wall of the housing toward a part of an outer circumferential surface of the stator core, wherein the part is located on a side of the other of the axially end portions of the stator core.

Abstract: A ball rotation amount measurement system which includes a magnetic sensor fixed to a ball to measure geomagnetism in at least one axis direction, and a computation unit configured to compute the rotation amount of the ball using data of a large number of the geomagnetism time-sequentially acquired by the magnetic sensor. The computation unit includes a difference data calculation unit configured to calculate a difference between two of the time-sequential geomagnetic data to thereby time-sequentially obtain a large number of difference data, a difference waveform calculation unit configured to determine a difference waveform that represents a time variation waveform of a large number of the difference data, and a rotation amount calculation unit configured to calculate the rotation amount of the ball, based on information of zero cross points at which the difference waveform crosses a straight line indicating zero-difference within a predetermined period.

Abstract: A flush toilet includes: a toilet main unit having a bowl portion, and a water conduit formed in the toilet main unit and configured to supply flush water into the bowl portion. The water conduit has: a first water-guiding portion extending from a water supply portion to a first spout port located on one of right and left sides of the bowl portion; and a second water-guiding portion extending from the water supply portion to a second spout port located on the other of the right and left sides of the bowl portion. The water supply portion is located at a right-sided or left-sided position in a right and left direction. The flush water is supplied to the water supply portion in a direction inclined with respect to a front and back direction and intersected with an inside surface of the water supply portion, as seen in plan view.

Abstract: The purpose of the present invention is to provide: a cancer stem cell having an excellent ability to form tumor tissue; and a method for establishing the cancer stem cell. Cells having a low metabolic function of 26S proteasome are isolated and concentrated from a cancer stem cell group containing cancer stem cells, thereby obtaining cancer stem cells which can form tumor tissue in a living body even when the number of cells is 200 or less.