Abstract: The present invention aims to provide a compound that may be useful for the prophylaxis or treatment of constipation and the like. The present invention provides a compound represented by the formula (I): wherein R1 is a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, or an optionally substituted C1-6 alkoxy group; and ring A is an optionally further substituted ring, or a salt thereof.

Abstract: A phosphor including a crystal phase of an aluminate compound containing a metal element M constituting a luminescent center ion and aluminum, in which the crystal phase contains crystallites, and an average size of the crystallites is 2 to 100 ?m.

Abstract: A pneumatic tire comprises a tread portion, a pair of sidewall portions, a pair of bead portions, a carcass extending between the portions, and an inner rubber extending between the portions, on the inner side of the carcass. The inner rubber comprises a first portion extending through the tread portion with a first thickness and a second portion extending through the sidewall portions with a second thickness smaller than the first thickness. The land ratio of the tread portion 2 is 65% or more.

Abstract: A pneumatic tire comprises: a tread portion having a ground contacting surface; a sidewall portions having an outer surface; a bead portions; a carcass extending between the bead portions; and an inner rubber extending between bead portions. The inner rubber comprises a first portion extending through the tread portion with a first thickness t1, and a second portion extending through the sidewall portion with a second thickness t2. The first thickness t1 is more than the second thickness t2. In a meridian cross section of the tire under its normal state, when a first reference point (Pb1), a second reference point (Pb2), a shoulder reference point (Ps), a reference line segment (Lb), and a shoulder line segment (Ls) are defined, then a length (L1) of the shoulder line segment (Ls) is 85.9% to 89.3% of a length (L2) of the reference line segment (Lb).

Abstract: A method for producing a phosphor having a core-shell structure that includes: a core part formed of a crystal phase of an inorganic compound containing a metal element M constituting a luminescent center ion and aluminum; and a shell part containing at least one element selected from the group consisting of boron and silicon and formed on at least a portion of a surface of the core part, the method including: mixing a raw material of the crystal phase and a raw material of the shell part; and heating the obtained mixture at a temperature at which the raw material of the shell part is liquefied, but a host crystal of a phosphor to be obtained is maintained, in which the raw material of the crystal phase contains a raw material compound having D50 in a particle diameter distribution of 0.2 to 90 ?m and containing aluminum.

Abstract: According to one embodiment, there is provided a multielement composite oxide powder that includes an oxide particle including a composite oxide, the composite oxide containing: constituent metal elements containing two or more hexavalent metal elements and two or more pentavalent metal elements at a content of 80 atm % or more in total; and oxygen. The oxide particle has a major axis and a minor axis intersecting the major axis, and has a polygonal tunnel structure including one or more polygonal tunnels of five or more vertices in a major axis direction along the major axis.

Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.

Abstract: A hair planting apparatus includes a mounting portion for mounting a base material where planting is performed, and including a work opening for planting, a hair planting unit for binding hair for planting to the base material in the work opening of the mounting portion, and a feed device disposed around the mounting portion and feeding the base material with a roller contacting the base material from below. In the hair planting apparatus, the feed device feeds the base material in at least two intersecting directions.

Abstract: A hair planting apparatus includes a mounting portion for mounting a base material, and including a work opening for planting, a hair planting unit for binding hair for planting to the material in the work opening, a transport mechanism for positioning the hair planting unit relative to each mesh hole of the material mounted on the mounting portion, an imaging unit for capturing images of a plurality of mesh holes of the material mounted on the mounting portion, a tilt detection unit for obtaining, from the image captured by the imaging unit, an alignment direction of the mesh holes of the material, and a correction mechanism for correcting the orientation of the material on the mounting portion according to a tilt angle of the alignment direction of the mesh holes of the material with respect to a predetermined direction.

Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.

Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.

Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.

Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.

Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.

Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.

Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) a S1P receptor agonist; and (b) a sugar alcohol.

Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.

Abstract: An optical head device may include a twin laser light source which is integrally provided with a first laser beam emitting element and a second laser beam emitting element, a light receiving element, and an optical system including an objective lens for converging a laser beam on an optical recording medium. The optical system is provided with a detection lens structured of a toric lens. The toric lens applies an astigmatic difference caused by a toric face to the one of the return light beams, and the toric lens applies the other of the return light beams an astigmatic difference caused by a toric face and astigmatism composed of astigmatism and curvature of image field caused by passing off-axis position to coincide a focusing position of the first laser beam with that of the second laser beam.

Abstract: An object of the present invention is to provide a black paste composition suitable for use in laser direct imaging devices employing a light source emitting a laser having a maximum wavelength of 350 to 420 nm, useful in forming a high-definition black matrix pattern efficiently, and superior in storage stability, a black matrix pattern formed by using the composition, a plasma display having the pattern, and a method of forming the black matrix pattern by using the composition. An alkali development-type black paste composition of the present invention comprises (A) a carboxyl group-containing resin, (B) a glass frit, (C) a black pigment, (D) a compound having at least one radically polymerizable unsaturated group in its molecule, and (E-1) an oxime-based photopolymerization initiator represented by the following general formula (I).

Abstract: Methods for pretreating and improving coking coal quality for producing blast-furnace coke by: (a) rapid-heating the coal charge in a fluidized-bed to a temperature range between not lower than 300° C. and not higher than the temperature at which the coal charge begins to soften, at a rate of 30 to 103 ° C./min., (b) classifying the rapid-heated coal charge to fine- and coarse-size coal, and then (c-1) briquetting the fine-size coal or (c-2) rapid-heating the fine- and coarse-size coal individually in a pneumatic preheater to a temperature range between not lower than 300° C. and not higher than the temperature at which the coal charge begins to soften, at a rate of 103 to 105 ° C./min., and (d) forming the fine-size coal.