Abstract: Provided is a system or the like capable of reducing mental burdens on an operator who remotely operates a work machine, when an image range acquired by a real machine image pickup device loaded on the work machine is changed. A previous notice indicating a future change mode of a real space area projected in a work environment image displayed at a remote image output device 221 is output to a remote output interface 220. It is possible to make the operator who encounters a virtual sound source Vss displaced according to a displacement mode of the real space area and/or an icon image A1 in an arrow shape indicating the displacement mode of the real space area recognize beforehand that the real space area projected in the work environment image is to be displaced according to the displacement mode in the future.

Abstract: Provided is a structure for individual authentication in which a pillar pattern region including a plurality of nanopillars formed of synthetic quartz glass is formed on at least a part of a surface portion of a synthetic quartz glass substrate. In the pillar pattern region, the nanopillars have an indentation elastic modulus of 35 to 100 GPa as measured by a nanoindentation method, and the nanopillars are plastically deformed.

Abstract: There is provided an imaging lens with excellent optical characteristics which satisfies demand of wide field of view and low F-number. An imaging lens comprising in order from an object side to an image side, a first lens with negative refractive power in a paraxial region, a second lens with positive refractive power having a convex object-side surface in a paraxial region, a third lens with positive refractive power in a paraxial region, a fourth lens, a fifth lens having a concave object-side surface in a paraxial region, and a sixth lens having a concave image-side surface in a paraxial region, and predetermined conditional expressions are satisfied.

Abstract: An objective of the present invention is to provide non-human animal models of cancer pathology, which mimic the hierarchical organization, cancer progression process, or biological property of human cancer tissues, and uses thereof. To achieve the objective described above, first, the present inventors transplanted cells of NOG-established cancer lines into NOG mice and morphologically observed the resulting tissue organization. As a result, the non-human animal models were demonstrated to exhibit pathologies (the hierarchical organization, cancer progression process, or biological properties of the cancer cells) similar to that of human cancer. Specifically, the present inventors succeeded in preparing non-human animal models exhibiting pathologies more similar to a human cancer, and cell culture systems using NOG-established cancer cell lines where the in vitro cell morphology is more similar to that of human cancer.

Abstract: An objective of the present invention is to provide non-human animal models of cancer pathology, which mimic the hierarchical organization, cancer progression process, or biological property of human cancer tissues, and uses thereof. To achieve the objective described above, first, the present inventors transplanted cells of NOG-established cancer lines into NOG mice and morphologically observed the resulting tissue organization. As a result, the non-human animal models were demonstrated to exhibit pathologies (the hierarchical organization, cancer progression process, or biological properties of the cancer cells) similar to that of human cancer. Specifically, the present inventors succeeded in preparing non-human animal models exhibiting pathologies more similar to a human cancer, and cell culture systems using NOG-established cancer cell lines where the in vitro cell morphology is more similar to that of human cancer.

Abstract: An assistance device includes: an object information acquirer that acquires information regarding an object installed in a living space, in which the object is to be reformed, repaired, or produced; a detection information acquirer that acquires a history of detection information detected in the past by a sensor installed in the living space; and a candidate presentation unit that generates and presents a candidate for a method for renovating, repairing, or producing the object, based on information regarding the object acquired by the object information acquirer and a history of the detection information acquired by the detection information acquirer.

Abstract: An imaging lens includes: arranged in order from an object side to an image side IM, a first lens L1 having positive refractive power; a second lens L2 having negative refractive power; a third lens L3 having positive refractive power; a fourth lens L4 having positive refractive power; a fifth lens L5; a sixth lens L6; a seventh lens L7 having negative refractive power; and an eighth lens L8 having negative refractive power, wherein an object-side surface of the sixth lens L6 is concave in a paraxial region, and an object-side surface of the eighth lens L8 is convex in the paraxial region.

Abstract: There is provided an imaging lens with excellent optical characteristics which satisfies demand of a low profile and a low F-number. An imaging lens comprises in order from an object side to an image side, a first lens with positive refractive power, a second lens with negative refractive power, a third lens, a fourth lens with positive refractive power, and a fifth lens with negative refractive power, wherein said first lens has an object-side surface being convex in a paraxial region, said third lens has an image-side surface being convex in a paraxial region, and said fifth lens is formed in a biconcave shape having an object-side surface being concave and an image-side surface being concave in the paraxial region, and predetermined conditional expressions are satisfied.

Abstract: An imaging lens includes: arranged in order from an object side to an image side, a first lens L1 having positive refractive power; a second lens L2 having negative refractive power; a third lens L3 having positive refractive power; a fourth lens L4 having negative refractive power; a fifth lens L5; a sixth lens L6; a seventh lens L7; and an eighth lens L8 having negative refractive power, wherein the eighth lens has an aspheric image-side surface having at least one inflection point, and a conditional expression below is satisfied: ?12.0<f4/f<?3.0 where f: a focal length of entire optical system of the imaging lens, and f4: a focal length of the fourth lens.

Abstract: There is provided an imaging lens with excellent optical characteristics which satisfies demand of a low profile and a low F-number. An imaging lens comprises in order from an object side to an image side, a first lens with positive refractive power, a second lens with positive or negative refractive power, a third lens with positive or negative refractive power, a fourth lens, a fifth lens with negative refractive power, a sixth lens with positive refractive power, and a seventh lens with negative refractive power, wherein said first lens has an object-side surface being convex in a paraxial region, said third lens has an object-side surface being convex in a paraxial region, said fifth lens is formed in a biconcave shape having an object-side surface and an image-side surface being concave in a paraxial region, and said seventh lens has an image-side surface being concave in a paraxial region, and predetermined conditional expressions are satisfied.

Abstract: There is provided an imaging lens with excellent optical characteristics which satisfies demand of wide field of view and low F-number. An imaging lens comprising in order from an object side to an image side, a first lens with negative refractive power in a paraxial region, a second lens with positive refractive power having a convex object-side surface in a paraxial region, a third lens with positive refractive power in a paraxial region, a fourth lens, a fifth lens having a concave object-side surface in a paraxial region, and a sixth lens having a concave image-side surface in a paraxial region, and predetermined conditional expressions are satisfied.

Abstract: A space management device includes: a space information retaining unit that retains information regarding a living space including a building or premises where a person lives, lodges, or stays; a condition retaining unit that retains a condition regarding a position of a person or a movable body in the living space; a position information acquirer that acquires, from a detection device for detecting identification information and position information of a person or a movable body present in the living space, the identification information and position information; and a determination unit that refers to a condition retained in the condition retaining unit to determine whether or not a person or a movable body present in the living space is allowed to stay at the position or move to another position, based on the identification information and position information acquired by the position information acquirer.

Abstract: Provided are methods for culturing a cancer stem cell-derived tissue, which comprise the step of three-dimensionally culturing a cancer stem cell-derived tissue after treating it with a therapeutic agent for diseases. The culture methods of the present disclosure enable the construction of cell clusters analogous to therapeutic agent-resistant tissues which are characteristically seen in tissues of patients who have actually been administered with a therapeutic agent for diseases. The cell clusters of the present disclosure are useful for elucidating the mechanism for acquiring anticancer agent resistance, identifying a therapeutic target therefor, or screening for a therapeutic agent. The preferred disease in the present disclosure is cancer.

Abstract: A gear position of a multi-position transmission, which shifts and drives a vehicle according to a turn motion of a shift drum, is detected by a plurality of sensors. An end portion of the shift drum is fitted with an end portion of an elongated shaft rotated coaxially with the shift drum. A first sensor which is fitted to other end portion of the elongated shaft detects a turn position of the elongated shaft. A second sensor which is located outside in a radial direction of the elongated shaft between the one end portion and the other end portion of the elongated shaft detects that the elongated shaft is located at a specified turn position. The first sensor and the second sensor are fitted from the outside of a transmission case of the multi-position transmission and are exposed to the outside of the transmission case.

Abstract: An imaging lens is provided with: a first lens with negative power; a second lens with negative power; a third lens with positive power; and a fourth lens with positive power. The cemented fourth lens is formed from an object side lens with negative power and an image side lens with positive power. The thickness of a resin adhesive layer that bonds the object side lens and the image side lens is 20 ?m or greater on the optical axis, and when Sg1H is the amount of sag in the image side lens surface of the object side lens and Sg2H is the amount of sag in the object side lens surface of the image side lens. The bonding operation is easy without damage occurring to the cemented surfaces, with a design that takes into account thickness of the resin adhesive layer; therefore various forms of aberration can be corrected.

Abstract: An imaging lens is provided with: a first lens with negative power; a second lens with negative power; a third lens with positive power; and a fourth lens with positive power. The cemented fourth lens is formed from an object side lens with negative power and an image side lens with positive power. The thickness of a resin adhesive layer that bonds the object side lens and the image side lens is 20 ?m or greater on the optical axis, and when Sg1H is the amount of sag in the image side lens surface of the object side lens and Sg2H is the amount of sag in the object side lens surface of the image side lens. The bonding operation is easy without damage occurring to the cemented surfaces, with a design that takes into account thickness of the resin adhesive layer; therefore various forms of aberration can be corrected.

Abstract: A gear position detecting device includes a rotation angle sensor for detecting a turn position of a shift drum and a position sensor for detecting that the shift drum is at a neutral position. The rotation angle sensor is a volume sensor that linearly increases or decreases an output voltage according to a turning motion of the shift drum. The neutral position is set in such a way as not to overlap a dead zone. It is determined according to an output signal of the rotation angle sensor and an output signal of the position sensor whether the shift drum is at a reverse gear position located between the neutral position and the dead zone or a fifth gear position turned by 360 degrees from the reverse gear position. Such detecting device detects a gear position with a high accuracy even if the number of gear positions are increased.

Abstract: An imaging lens is formed from a first group lens having negative power, a second group lens having positive power, a third group lens having negative power, and a fourth group lens having positive power, disposed in order from the subject side to the image side. Letting f be the focal distance for the entire lens system and ff2 the focal distance for the second group lens, 1.0?ff2/f?2.0 is satisfied; therefore, the entire length of the lens system can be kept short and image curvature can be suppressed. In addition, each of the subject side lens surfaces and the image side lens surfaces for the second group lens, third group lens, and fourth group lens are provided with aspherical surface shapes; therefore, the imaging lens is constituted to be bright.

Abstract: An imaging lens is formed from a first group lens having negative power, a second group lens having positive power, a third group lens having negative power, and a fourth group lens having positive power, disposed in order from the subject side to the image side. Letting f be the focal distance for the entire lens system and ff2 the focal distance for the second group lens, 1.0?ff2/f?2.0 is satisfied; therefore, the entire length of the lens system can be kept short and image curvature can be suppressed. In addition, each of the subject side lens surfaces and the image side lens surfaces for the second group lens, third group lens, and fourth group lens are provided with aspherical surface shapes; therefore, the imaging lens is constituted to be bright.

Abstract: According to one embodiment, an apparatus for generating an occupancy grid map constituted with a two-dimensional grid around a first moving body includes processing circuitry configured to acquire data of a distance from the first moving body to an obstacle lying in surroundings of the first moving body; acquire first information indicating the movement status of the first moving body at current time and determine an operation mode of the first moving body; set a range of interest in a grid of a resolution higher than a resolution of the grid of the occupancy grid map, from the operation mode; and align the occupancy grid map to the range of interest and generate the occupancy grid map in such a manner that the obstacle exists in the grid of the occupancy grid map and the grid of the range of interest with respect to a position corresponding to the distance data.