Abstract: A dispensing tip holder is used when a dispensing tip is attached to a tip of a pipette, and includes a peripheral wall having a shape surrounding an outer peripheral surface of the dispensing tip, and an insertion portion having an insertion opening into which the dispensing tip is to be inserted. The peripheral wall has a first end into which the dispensing tip is to be inserted, and has a second end provided at a position opposite to the first end. The insertion portion is formed in the peripheral wall such that an outer peripheral surface of the dispensing tip abuts against an edge of the insertion opening, and is formed in the peripheral wall such that a tip of the dispensing tip does not project from the second end of the peripheral wall, when the dispensing tip is inserted into the insertion opening from the first end.

Abstract: A magnetic particle manipulating apparatus includes a magnetic force source moving mechanism, an operation controller configured to control operation of the magnetic source moving mechanism, an openable cover for covering the device holder, a pressing mechanism provided on the cover to press the tubular device held by the device holder when the cover is closed so that warpage of the tubular device is corrected, an open/close state detector provided so as to detect an open/close state of the cover. The operation controller is configured to execute the processing operation only in a case where the open/close state detector detects that the cover is closed.

Abstract: A manufacturing method of an operation pipe, which use a gel to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components that are biological components such as nucleic acids. More specifically, a manufacturing method of an operation pipe, with which it is possible to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components in a sealable pipe by operating magnetic particles in the pipe under a magnetic field from outside of the pipe.

Abstract: A preprocessing apparatus uses preprocessing kits prepared for samples, respectively, sets the preprocessing kits in plural processing ports provided so as to correspond to preprocessing items, and executes a predetermined preprocessing item. A controller which controls operations of a carrying mechanism holding and carrying the preprocessing kits, and processing parts executing the preprocessing items in the respective processing ports, includes a processing-state control part, a random access part, and a preprocessing part. The random access part is configured to check availability of a preprocessing port corresponding to a preprocessing item to be executed on a sample contained in a preprocessing kit, and set the preprocessing kit in a processing port if the processing port is available as a processing port corresponding to the preprocessing item. The preprocessing part executes a corresponding preprocessing item on a sample in a preprocessing kit when the preprocessing kit is set in the processing port.

Abstract: The present invention relates to a method for simultaneously detecting a plurality of pathogens from biologically-derived samples, and a kit for carrying out the method. Specifically, the present invention relates to a method for simultaneously detecting a plurality of pathogens that cause infectious uveitis, one of eye infections from samples such as anterior chamber fluid or vitreous by polymerase chain reaction (PCR), and a kit for carrying out the method.

Abstract: A purpose of the present invention is to suppress reduction in recovery rate of a target component due to a gel adhering to an inner wall surface of a treatment liquid layer. After passing magnetic particles through a gel layer, when moving the magnetic particles in the treatment liquid layer adjacent to the gel layer, the magnetic force source is automatically operated in a longitudinal direction of a tubular container so that the magnetic particles do not enter a range of a certain distance from the gel layer through which the magnetic particles have passed.

Abstract: This invention provides a simple analysis method by a PCR method that simultaneously performs, in a single container, separating nucleic acid of pathogens contained in a tissue fragment and preparing a PCR buffer solution, and a kit used for the analysis method. A method for detecting a pathogen includes: (1) obtaining a liquid specimen mixture by adding a tissue fragment containing a pathogen to a PCR buffer solution containing a proteolytic enzyme; (2) heating the liquid specimen mixture at a first temperature; (3) further heating at a second temperature; (4) performing PCR by adding a portion of the liquid mixture obtained in (3) above to a solid composition for PCR reaction containing DNA polymerase and one or more kinds of PCR primer pair; and (5) detecting a PCR product generated in (4) above.

Abstract: The present invention relates to a method for operating magnetic particles in a device in which gel-like medium layer and liquid layer are alternately arranged inside the hollow tube and, first liquid layer and second liquid layer are separated by gel-like medium layer, and magnetic solid with large particle size exists in the first liquid layer rather than magnetic particles and the said magnetic particles. The method of the present invention comprises the first step of moving the magnetic particles and the magnetic solid in the first liquid layer to the gel-like medium layer, the second step of moving the magnetic particles and the magnetic solid moved into the gel-like medium layer into the second liquid layer, and the third step of inverting the movement of the magnetic particles and the magnetic solid moved into the second liquid layer into the gel-like medium layer, by operating a magnetic field.

Abstract: A reaction vessel has plural wells each configured to accommodate a sample on the same plane or on the same straight line. Among the wells of a well plate, a specific well other than a well at a center of point symmetry is an orientation recognizing well in which a fluorescent dye is placed. The reaction vessel can identify a position of the orientation recognizing well by using fluorescence emitted from the fluorescent dye, and can thereby recognize an orientation of the reaction vessel.

Abstract: A dispensing tip holder is used when a dispensing tip is attached to a tip of a pipette, and includes a peripheral wall having a shape surrounding an outer peripheral surface of the dispensing tip, and an insertion portion having an insertion opening into which the dispensing tip is to be inserted. The peripheral wall has a first end into which the dispensing tip is to be inserted, and has a second end provided at a position opposite to the first end. The insertion portion is formed in the peripheral wall such that an outer peripheral surface of the dispensing tip abuts against an edge of the insertion opening, and is formed in the peripheral wall such that a tip of the dispensing tip does not project from the second end of the peripheral wall, when the dispensing tip is inserted into the insertion opening from the first end.

Abstract: The present invention relates to a method for simultaneously detecting a plurality of pathogens from biologically-derived samples, and a kit for carrying out the method. Specifically, the present invention relates to a method for simultaneously detecting a plurality of pathogens that cause infectious uveitis, one of eye infections from samples such as anterior chamber fluid or vitreous by polymerase chain reaction (PCR), and a kit for carrying out the method.

Abstract: To improve a sealing property of a reaction container over a period before and after implementing gene amplification processing. A gene amplification device includes: a reaction container holder having a container insertion part into which a main body of a reaction container including the main body and a lid attached to an upper portion of the main body is inserted, the reaction container holder having a function of raising and lowering a temperature of the reaction container inserted into the container insertion part; and a heat seal part disposed near an contacting portion between the main body and the lid of the reaction container inserted into the container insertion part of the reaction container holder, the heat seal part heating a temperature of the contacting portion to a temperature higher than a heatproof temperature of the main body or the lid of the reaction container.

Abstract: An operation pipe and a device equipped with the operation pipe, which use a gel to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components that are biological components such as nucleic acids. More specifically, an operation pipe and a device, with which it is possible to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components in a sealable pipe by operating magnetic particles in the pipe under a magnetic field from outside of the pipe.

Abstract: A container has a tubular form, and has gel-like medium layers and liquid layers alternately stacked in a longitudinal direction. Magnetic particles, having a target substance immobilized thereon and loaded inside the container, can be moved sequentially through the gel-like medium layers and the liquid layers by moving an external magnet. The container has an information holding part that holds identification information. The identification information is correlated to a control program product for moving the magnet.

Abstract: A magnet is disposed close to and outside a container held by a container holding part, and relatively moves along the container, so as to move the magnetic particles in the container by a magnetic force. A housing accommodates the magnet and the container holding part in the housing in a state where a position of the magnet relatively moving along the container is not visually recognizable from the outside. A display unit is provided on the housing so as to be visually recognizable from the outside and has light emitting regions that can emit light. A processing step execution unit sequentially executes a plurality of processing steps by relatively moving the magnet. When the plurality of processing steps are sequentially executed, a light emission control unit causes the light emitting regions to emit light according to a position of the magnet.

Abstract: Disclosed herein is a reagent preparation supporting device including: reagent kit information storing means that stores amounts of reagents required for one analysis and a composition of a reaction liquid to be prepared; an input unit that inputs the number of samples to be analyzed; reagent amount calculating means that calls up, from the reagent kit information storing means, the data regarding the reagent kit to calculate required amounts of the reagents included in the reagent kit and a composition of the reaction liquid according to the number of samples inputted through the input unit; and a display unit that displays, as a reagent preparation table, the required amounts of the reagents included in the reagent kit and the composition of the reaction liquid to be prepared based on results calculated by the reagent amount calculating means.

Abstract: A gene measurement apparatus includes: a temperature control block that is provided with, on its upper surface, a plurality of reaction vessel wells each being used to house a reaction vessel, and that performs temperature treatment on a specimen in the reaction vessel by controlling temperature of the plurality of reaction vessel wells using a heating element or a cooling element; and a reaction vessel detector configured to detect whether the reaction vessel is housed in each of the plurality of reaction vessel wells of the temperature control block before the temperature treatment is started.

Abstract: A stool collection container includes: a stool collection container main body having a structure in which a stick holder for holding a stool collection stick is detachably mounted on one end side while the stool collection part and the stool collection stick are housed inside; and a collection needle penetrating through a wall surface of the another end side of the stool collection container main body so that a tip thereof is inserted into the stool collection container main body, the collection needle being provided so as to be detachable from the stool collection container main body. When the stick holder is mounted on one end side of the stool collection container main body, the tip of the collection needle is inserted into the opening of the stool collection part housed inside the stool collection container main body.

Abstract: A stool collection container includes: a stool collection container main body having a structure in which a stick holder for holding a stool collection stick is detachably mounted on one end side while the stool collection part and the stool collection stick are housed inside; and a collection needle penetrating through a wall surface of the another end side of the stool collection container main body so that a tip thereof is inserted into the stool collection container main body, the collection needle being provided so as to be detachable from the stool collection container main body. When the stick holder is mounted on one end side of the stool collection container main body, the tip of the collection needle is inserted into the opening of the stool collection part housed inside the stool collection container main body.

Abstract: A gene polymorphism analysis device for determining the allele mating type of a gene polymorphism on the basis of the first fluorescence intensity change over time and the second fluorescence intensity change over time measured on the first allele and second allele that constitute a gene polymorphism of a target DNA. The determination of the allele mating type of the gene polymorphism is performed on samples arranged in M rows and N columns, and the determination results and graphs are displayed on a display device. The graphs show the first fluorescence intensity change over time and the second fluorescence intensity change over time of each sample. The determination results and the graphs are arranged in M rows and N columns so as to correspond to the layout including M rows and N columns of the samples.