Patents by Inventor Masanori Sugita

Masanori Sugita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5380723
    Abstract: Disclosed are indole derivatives of formula (I) ##STR1## wherein X and Y each independently represent H or --CH.sub.2 CH.sub.2 R; R represents pyridyl or substituted amino of NR.sub.1 R.sub.2 ;R.sub.1 represents H or C.sub.1 -C.sub.6 alkyl;R.sub.2 represents 2-(3-indolyl)ethyl or aralkyl; orR.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached may form an N-containing 5 to 6 membered hetero ring, an N, O-containing hetero ring, which hetero ring may be fused with benzene;n is an integer of 4 to 8;with the proviso that X and Y both do not represent H or piperizinoethyl when n is 4, or pharmaceuticaly acceptable acid addition salts thereof. They are useful as an antiulcer agent.
    Type: Grant
    Filed: April 15, 1994
    Date of Patent: January 10, 1995
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Toshihiro Takahashi, Hitoshi Inoue, Masato Horigome, Kenichi Momose, Masanori Sugita, Kouichi Katsuyama, Chikako Suzuki, Shinji Nagai, Masao Nagase, Koichi Nakamaru
  • Patent number: 5326879
    Abstract: Disclosed are indole derivatives of formula (I) ##STR1## wherein X and Y each independently represent H or --CH.sub.2 CH.sub.2 R;R represents pyridyl or substituted amino of NR.sub.1 R.sub.2 ;R.sub.1 represents H or C.sub.1 -C.sub.6 alkyl;R.sub.2 represents 2-(3-indolyl)ethyl or aralkyl; orR.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached may form an N-containing 5 to 6 membered hetero ring, an N, O-containing hetero ring, which hetero ring may be fused with benzene;n is an integer of 4 to 8;with the proviso that X and Y both do not represent H or piperizinoethyl when n is 4, or pharmaceuticaly acceptable acid addition salts thereof. They are useful as an antiulcer agent.
    Type: Grant
    Filed: September 22, 1992
    Date of Patent: July 5, 1994
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Toshihiro Takahashi, Hitoshi Inoue, Masato Horigome, Kenichi Momose, Masanori Sugita, Kouichi Katsuyama, Chikako Suzuki, Shinji Nagai, Masao Nagase, Koichi Nakamaru
  • Patent number: 5252580
    Abstract: Disclosed are indole derivatives of formula (I) ##STR1## wherein Y represents H, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy or halogen;Z represents --CH.sub.2 N(R.sub.5)--;R represents H or --CH.sub.2 CH.sub.2 X where X represents pyridyl, aralkyloxy or substituted amino of NR.sub.6 R.sub.7 where R.sub.6 represents H, C.sub.1 -C.sub.6 alkyl, aralkyl, C.sub.1 -C.sub.6 alkoxycarbonyl, aralkyloxycarbonyl or halogenated C.sub.1 -C.sub.6 alkoxycarbonyl and R.sub.7 represents H, C.sub.1 -C.sub.6 alkyl or aralkyl, or together with R.sub.2 may form a ring of --(CH.sub.2).sub.n -- (n is 1-4) or ##STR2## R.sub.1 represents H, C.sub.1 -C.sub.6 alkyl, aralkyl or arylsulfonyl; R.sub.2 represents C.sub.1 -C.sub.6 alkyl, hydroxy, C.sub.1 -C.sub.6 alkoxy or aralkyloxy;R.sub.3 represents H, C.sub.1 -C.sub.6 alkyl, aralkyl or halogenated C.sub.1 -C.sub.6 alkyl;R.sub.4 and R.sub.5 may be the same or different and each represents H, C.sub.1 -C.sub.6 alkyl or aralkyl or both may together form a ring of --(CH.sub.2).sub.
    Type: Grant
    Filed: September 18, 1992
    Date of Patent: October 12, 1993
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Toshihiro Takahashi, Hitoshi Inoue, Masato Horigome, Kenichi Momose, Masanori Sugita, Kouichi Katsuyama, Chikako Suzuki, Shinji Nagai, Masao Nagase, Koichi Nakamaru
  • Patent number: 5217398
    Abstract: A pedal operated catamaran includes a pair of side-by-side buoyant hulls, and a rigid frame releasably mounted to the hulls in one of two alternative positions, to maintain the hulls parallel to one another. The catamaran includes a propeller mounted for rotation with an elongated, longitudinal propeller drive shaft. A gear train drivably associates the propeller drive shaft and a crankshaft, for propeller rotation responsive to rotation of the crankshaft. The propeller drive shaft further is pivotally mounted to allow selective alternative latching of the propeller in a retracted position and in one of several operating positions, as controlled by a hand-operated lever. The latching mechanism allows on-the-fly adjustment of the propeller position. In the retracted position, the propeller is automatically angularly locked above the hulls, to facilitate car top carrying of the craft without disassembly.
    Type: Grant
    Filed: April 14, 1992
    Date of Patent: June 8, 1993
    Assignee: Yamaha Hatsudoki Kabushiki Kaisha
    Inventors: Abraham Meron, Masanori Sugita
  • Patent number: 5182267
    Abstract: A pharmaceutical oil-in-water type microemulsion having an action of potentiating the activities of anti-cancer agents, said micro-emulsion comprisesfine particles of a vegetable oil or a triglyceride of a medium-chain fatty acid having 8 to 12 carbon atoms containing 0.1 to 10% (w/v) of N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine malate of formula (I) below, ##STR1## an aqueous medium, and 0.05 to 25% (w/v) of a physiologically acceptable phospholipid for dispersing said fine particles in said aqueous medium.
    Type: Grant
    Filed: December 12, 1990
    Date of Patent: January 26, 1993
    Assignees: Lederle (Japan), Ltd., Nisshin Flour Milling Co., Ltd.
    Inventors: Osamu Ogawa, Ikuo Kishi, Yoshiyuki Tahara, Masanori Sugita
  • Patent number: 5060745
    Abstract: An improved drive unit and suspension arrangement therefor for a small snowmobile having an open tubular frame. The drive unit includes an internal combustion engine and a pulley type transmission. The pulley type transmission is supported within a transmission casing and is affixed to the frame for rigidifying the frame. The suspension permits more vertical compliance than for and aft compliance for vibration dampening without adversely effecting the rigidity.
    Type: Grant
    Filed: February 15, 1990
    Date of Patent: October 29, 1991
    Assignee: Yamaha Hatsudoki Kabushiki Kaisha
    Inventors: Toshihiro Yasui, Masanori Sugita, Tsuneo Isobe, Haruhiko Nakanosono
  • Patent number: 5004756
    Abstract: A pharmaceutical oil-in-water type microemulsion having an action of potentiating the activities of anti-cancer agents, said micro-emulsion comprises fine particles of a vegetable oil or a triglyceride of a medium-chain fatty acid having 8 to 12 carbon atoms containing 0.1 to 10% (w/v) of N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine malate of formula (I) below, ##STR1## an aqueous medium, and, 0.05 to 25% (w/v) of a physiologically acceptable phospholipid for dispersing said fine particles in said aqueous medium.
    Type: Grant
    Filed: August 8, 1989
    Date of Patent: April 2, 1991
    Assignees: Lederle (Japan) Ltd., Nisshin Flour Milling Co., Ltd.
    Inventors: Osamu Ogawa, Ikuo Kishi, Yoshiyuki Tahara, Masanori Sugita
  • Patent number: 4917207
    Abstract: An improved drive unit and suspension arrangement therefor for a small snowmobile having an open tubular frame. The drive unit includes an internal combustion engine and a pulley type transmission. The pulley type transmission is supported within a transmission casing and is affixed to the frame for rigidifying the frame. The suspension permits more vertical compliance than fore and aft compliance for vibration dampening without adversely effecting the rigidity.
    Type: Grant
    Filed: February 29, 1988
    Date of Patent: April 17, 1990
    Assignee: Yamaha Hatsudoki Kabushiki Kaisha
    Inventors: Toshihiro Yasui, Masanori Sugita, Tsuneo Isobe, Haruhiko Nakanosono
  • Patent number: 4892165
    Abstract: A small snowmobile embodying a light weight welded up tubular frame assembly that has a generally open configuration for facilitating servicing and which is the nevertheless extremely robust.
    Type: Grant
    Filed: March 1, 1988
    Date of Patent: January 9, 1990
    Assignee: Yamaha Hatsudoki Kabushiki Kaisha
    Inventors: Toshihiro Yasui, Masanori Sugita
  • Patent number: 4892164
    Abstract: A frame and body construction for a small snowmobile comprised of a generally open tubular frame to which a light weight generally inverted cup shape body is detachably connected. To prevent carburetor icing, an insulating box encircles the carburetor and cooperates with the body, when the body is in place.
    Type: Grant
    Filed: March 2, 1988
    Date of Patent: January 9, 1990
    Assignee: Yamaha Hatsuodoki Kabushiki Kaisha
    Inventors: Toshihiro Yasui, Masanori Sugita, Tsuneo Isobe
  • Patent number: 4649135
    Abstract: Mycotrienin-related compounds called the T-23-X, -XI, -XII, -XIII and -XIV. These compounds are isolated and characterized by structural formula and other identifying data. They are useful in the treatment of tumors.
    Type: Grant
    Filed: April 15, 1986
    Date of Patent: March 10, 1987
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Noboru Otake, Haruo Seto, Tetsuo Sasaki, Masanori Sugita, Shigeru Hiramoto
  • Patent number: 4587237
    Abstract: Mycotrienin-related compounds called the T-23-VIII and T-23-IX substances. These substances are isolated and characterized by structural formula and other identifying data. These substances are useful in the treatment of tumors.
    Type: Grant
    Filed: September 6, 1985
    Date of Patent: May 6, 1986
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Noboru Otake, Haruo Seto, Tetsuo Sasaki, Masanori Sugita, Shigeru Hiramoto
  • Patent number: 4521339
    Abstract: The disclosure describes a microbiological process for the preparation of mycotrien-related compounds.The compounds are isolated and characterized by structural formula and other identifying data.The compounds are useful in the treatment of tumors.
    Type: Grant
    Filed: November 24, 1982
    Date of Patent: June 4, 1985
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Noboru Otake, Haruo Seto, Tetsuo Sasaki, Masanori Sugita, Yohei Natori, Noriyoshi Sueda