Patents by Inventor Masanori Sugita
Masanori Sugita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5380723Abstract: Disclosed are indole derivatives of formula (I) ##STR1## wherein X and Y each independently represent H or --CH.sub.2 CH.sub.2 R; R represents pyridyl or substituted amino of NR.sub.1 R.sub.2 ;R.sub.1 represents H or C.sub.1 -C.sub.6 alkyl;R.sub.2 represents 2-(3-indolyl)ethyl or aralkyl; orR.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached may form an N-containing 5 to 6 membered hetero ring, an N, O-containing hetero ring, which hetero ring may be fused with benzene;n is an integer of 4 to 8;with the proviso that X and Y both do not represent H or piperizinoethyl when n is 4, or pharmaceuticaly acceptable acid addition salts thereof. They are useful as an antiulcer agent.Type: GrantFiled: April 15, 1994Date of Patent: January 10, 1995Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Toshihiro Takahashi, Hitoshi Inoue, Masato Horigome, Kenichi Momose, Masanori Sugita, Kouichi Katsuyama, Chikako Suzuki, Shinji Nagai, Masao Nagase, Koichi Nakamaru
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Patent number: 5326879Abstract: Disclosed are indole derivatives of formula (I) ##STR1## wherein X and Y each independently represent H or --CH.sub.2 CH.sub.2 R;R represents pyridyl or substituted amino of NR.sub.1 R.sub.2 ;R.sub.1 represents H or C.sub.1 -C.sub.6 alkyl;R.sub.2 represents 2-(3-indolyl)ethyl or aralkyl; orR.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached may form an N-containing 5 to 6 membered hetero ring, an N, O-containing hetero ring, which hetero ring may be fused with benzene;n is an integer of 4 to 8;with the proviso that X and Y both do not represent H or piperizinoethyl when n is 4, or pharmaceuticaly acceptable acid addition salts thereof. They are useful as an antiulcer agent.Type: GrantFiled: September 22, 1992Date of Patent: July 5, 1994Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Toshihiro Takahashi, Hitoshi Inoue, Masato Horigome, Kenichi Momose, Masanori Sugita, Kouichi Katsuyama, Chikako Suzuki, Shinji Nagai, Masao Nagase, Koichi Nakamaru
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Patent number: 5252580Abstract: Disclosed are indole derivatives of formula (I) ##STR1## wherein Y represents H, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy or halogen;Z represents --CH.sub.2 N(R.sub.5)--;R represents H or --CH.sub.2 CH.sub.2 X where X represents pyridyl, aralkyloxy or substituted amino of NR.sub.6 R.sub.7 where R.sub.6 represents H, C.sub.1 -C.sub.6 alkyl, aralkyl, C.sub.1 -C.sub.6 alkoxycarbonyl, aralkyloxycarbonyl or halogenated C.sub.1 -C.sub.6 alkoxycarbonyl and R.sub.7 represents H, C.sub.1 -C.sub.6 alkyl or aralkyl, or together with R.sub.2 may form a ring of --(CH.sub.2).sub.n -- (n is 1-4) or ##STR2## R.sub.1 represents H, C.sub.1 -C.sub.6 alkyl, aralkyl or arylsulfonyl; R.sub.2 represents C.sub.1 -C.sub.6 alkyl, hydroxy, C.sub.1 -C.sub.6 alkoxy or aralkyloxy;R.sub.3 represents H, C.sub.1 -C.sub.6 alkyl, aralkyl or halogenated C.sub.1 -C.sub.6 alkyl;R.sub.4 and R.sub.5 may be the same or different and each represents H, C.sub.1 -C.sub.6 alkyl or aralkyl or both may together form a ring of --(CH.sub.2).sub.Type: GrantFiled: September 18, 1992Date of Patent: October 12, 1993Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Toshihiro Takahashi, Hitoshi Inoue, Masato Horigome, Kenichi Momose, Masanori Sugita, Kouichi Katsuyama, Chikako Suzuki, Shinji Nagai, Masao Nagase, Koichi Nakamaru
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Patent number: 5217398Abstract: A pedal operated catamaran includes a pair of side-by-side buoyant hulls, and a rigid frame releasably mounted to the hulls in one of two alternative positions, to maintain the hulls parallel to one another. The catamaran includes a propeller mounted for rotation with an elongated, longitudinal propeller drive shaft. A gear train drivably associates the propeller drive shaft and a crankshaft, for propeller rotation responsive to rotation of the crankshaft. The propeller drive shaft further is pivotally mounted to allow selective alternative latching of the propeller in a retracted position and in one of several operating positions, as controlled by a hand-operated lever. The latching mechanism allows on-the-fly adjustment of the propeller position. In the retracted position, the propeller is automatically angularly locked above the hulls, to facilitate car top carrying of the craft without disassembly.Type: GrantFiled: April 14, 1992Date of Patent: June 8, 1993Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Abraham Meron, Masanori Sugita
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Patent number: 5182267Abstract: A pharmaceutical oil-in-water type microemulsion having an action of potentiating the activities of anti-cancer agents, said micro-emulsion comprisesfine particles of a vegetable oil or a triglyceride of a medium-chain fatty acid having 8 to 12 carbon atoms containing 0.1 to 10% (w/v) of N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine malate of formula (I) below, ##STR1## an aqueous medium, and 0.05 to 25% (w/v) of a physiologically acceptable phospholipid for dispersing said fine particles in said aqueous medium.Type: GrantFiled: December 12, 1990Date of Patent: January 26, 1993Assignees: Lederle (Japan), Ltd., Nisshin Flour Milling Co., Ltd.Inventors: Osamu Ogawa, Ikuo Kishi, Yoshiyuki Tahara, Masanori Sugita
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Patent number: 5060745Abstract: An improved drive unit and suspension arrangement therefor for a small snowmobile having an open tubular frame. The drive unit includes an internal combustion engine and a pulley type transmission. The pulley type transmission is supported within a transmission casing and is affixed to the frame for rigidifying the frame. The suspension permits more vertical compliance than for and aft compliance for vibration dampening without adversely effecting the rigidity.Type: GrantFiled: February 15, 1990Date of Patent: October 29, 1991Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Toshihiro Yasui, Masanori Sugita, Tsuneo Isobe, Haruhiko Nakanosono
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Patent number: 5004756Abstract: A pharmaceutical oil-in-water type microemulsion having an action of potentiating the activities of anti-cancer agents, said micro-emulsion comprises fine particles of a vegetable oil or a triglyceride of a medium-chain fatty acid having 8 to 12 carbon atoms containing 0.1 to 10% (w/v) of N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine malate of formula (I) below, ##STR1## an aqueous medium, and, 0.05 to 25% (w/v) of a physiologically acceptable phospholipid for dispersing said fine particles in said aqueous medium.Type: GrantFiled: August 8, 1989Date of Patent: April 2, 1991Assignees: Lederle (Japan) Ltd., Nisshin Flour Milling Co., Ltd.Inventors: Osamu Ogawa, Ikuo Kishi, Yoshiyuki Tahara, Masanori Sugita
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Patent number: 4917207Abstract: An improved drive unit and suspension arrangement therefor for a small snowmobile having an open tubular frame. The drive unit includes an internal combustion engine and a pulley type transmission. The pulley type transmission is supported within a transmission casing and is affixed to the frame for rigidifying the frame. The suspension permits more vertical compliance than fore and aft compliance for vibration dampening without adversely effecting the rigidity.Type: GrantFiled: February 29, 1988Date of Patent: April 17, 1990Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Toshihiro Yasui, Masanori Sugita, Tsuneo Isobe, Haruhiko Nakanosono
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Patent number: 4892165Abstract: A small snowmobile embodying a light weight welded up tubular frame assembly that has a generally open configuration for facilitating servicing and which is the nevertheless extremely robust.Type: GrantFiled: March 1, 1988Date of Patent: January 9, 1990Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Toshihiro Yasui, Masanori Sugita
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Patent number: 4892164Abstract: A frame and body construction for a small snowmobile comprised of a generally open tubular frame to which a light weight generally inverted cup shape body is detachably connected. To prevent carburetor icing, an insulating box encircles the carburetor and cooperates with the body, when the body is in place.Type: GrantFiled: March 2, 1988Date of Patent: January 9, 1990Assignee: Yamaha Hatsuodoki Kabushiki KaishaInventors: Toshihiro Yasui, Masanori Sugita, Tsuneo Isobe
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Patent number: 4649135Abstract: Mycotrienin-related compounds called the T-23-X, -XI, -XII, -XIII and -XIV. These compounds are isolated and characterized by structural formula and other identifying data. They are useful in the treatment of tumors.Type: GrantFiled: April 15, 1986Date of Patent: March 10, 1987Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Noboru Otake, Haruo Seto, Tetsuo Sasaki, Masanori Sugita, Shigeru Hiramoto
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Patent number: 4587237Abstract: Mycotrienin-related compounds called the T-23-VIII and T-23-IX substances. These substances are isolated and characterized by structural formula and other identifying data. These substances are useful in the treatment of tumors.Type: GrantFiled: September 6, 1985Date of Patent: May 6, 1986Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Noboru Otake, Haruo Seto, Tetsuo Sasaki, Masanori Sugita, Shigeru Hiramoto
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Patent number: 4521339Abstract: The disclosure describes a microbiological process for the preparation of mycotrien-related compounds.The compounds are isolated and characterized by structural formula and other identifying data.The compounds are useful in the treatment of tumors.Type: GrantFiled: November 24, 1982Date of Patent: June 4, 1985Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Noboru Otake, Haruo Seto, Tetsuo Sasaki, Masanori Sugita, Yohei Natori, Noriyoshi Sueda