Patents by Inventor Masaru Yamakoshi

Masaru Yamakoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11959116
    Abstract: The present invention addresses the problem of providing a method for producing nicotinamide mononucleotide, that produces nicotinamide mononucleotide using a single enzyme and using nucleoside monophosphate, pyrophosphate, and nicotinamide as starting materials. This problem is solved by a nicotinamide mononucleotide production method that includes at least the following steps 1) and 2): 1) a first step of producing phosphoribosyl diphosphate by the action of substantially one enzyme on nucleoside monophosphate and pyrophosphate; and 2) a second step of producing nicotinamide mononucleotide by the action of only substantially the aforementioned one enzyme on nicotinamide and the phosphoribosyl diphosphate that is the product of the first step.
    Type: Grant
    Filed: October 26, 2022
    Date of Patent: April 16, 2024
    Assignee: ASAHI KASEI PHARMA CORPORATION
    Inventors: Takeshi Matsuoka, Tatsuya Hirata, Masaru Yamakoshi
  • Publication number: 20230125968
    Abstract: The present invention addresses the problem of providing a method for producing nicotinamide mononucleotide, that produces nicotinamide mononucleotide using a single enzyme and using nucleoside monophosphate, pyrophosphate, and nicotinamide as starting materials. This problem is solved by a nicotinamide mononucleotide production method that includes at least the following steps 1) and 2): 1) a first step of producing phosphoribosyl diphosphate by the action of substantially one enzyme on nucleoside monophosphate and pyrophosphate; and 2) a second step of producing nicotinamide mononucleotide by the action of only substantially the aforementioned one enzyme on nicotinamide and the phosphoribosyl diphosphate that is the product of the first step.
    Type: Application
    Filed: October 26, 2022
    Publication date: April 27, 2023
    Applicant: Asahi Kasei Pharma Corporation
    Inventors: Takeshi MATSUOKA, Tatsuya HIRATA, Masaru YAMAKOSHI
  • Publication number: 20090042279
    Abstract: It is intended to provide a noninvasive method of conveniently detecting mild impaired glucose tolerance and/or insulin hyposecretion at the early stage with the use of an enzyme. Namely, mild impaired glucose tolerance and/or insulin hyposecretion at the early stage are detected by quantifying myoinositol secreted into the urine before loading glucose and after loading glucose for a definite period of time with the use of a reagent and comparing the increase (or the increase ratio) in the myoinositol content thus measured with a characteristic level which has been preliminarily determined in normal subjects.
    Type: Application
    Filed: October 9, 2008
    Publication date: February 12, 2009
    Applicant: Asahi Kasei Pharma Corporation
    Inventors: Masaru YAMAKOSHI, Takuji Kouzuma
  • Patent number: 7452687
    Abstract: It is intended to provide a noninvasive method of conveniently detecting mild impaired glucose tolerance and/or insulin hyposecretion at the early stage with the use of an enzyme. Namely, mild impaired glucose tolerance and/or hyposecretion at the early stage are detected by quantifying myoinositol secreted into the urine before loading glucose and after loading glucose for a definite period of time with the use of a reagent and comparing the increase (or the increase ratio) in the myoinositol content thus measured with a characteristic level which has been preliminarily determined in normal subjects.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: November 18, 2008
    Assignee: Asahi Kasei Pharma Corporation
    Inventors: Masaru Yamakoshi, Takuji Kouzuma
  • Publication number: 20050214885
    Abstract: It is intended to provide a noninvasive method of conveniently detecting mild impaired glucose tolerance and/or insulin hyposecretion at the early stage with the use of an enzyme. Namely, mild impaired glucose tolerance and/or hyposecretion at the early stage are detected by quantifying myoinositol secreted into the urine before loading glucose and after loading glucose for a definite period of time with the use of a reagent and comparing the increase (or the increase ratio) in the myoinositol content thus measured with a characteristic level which has been preliminarily determined in normal subjects.
    Type: Application
    Filed: March 27, 2003
    Publication date: September 29, 2005
    Applicant: Asahi Kasei Pharma Corporation
    Inventors: Masaru Yamakoshi, Takuji Kouzuma
  • Patent number: 6794016
    Abstract: A water-resistant corrugated fiber board sheet having a high water resistance and capable of being recycled after the use contains a water-resistant linerboard adhered to both surfaces of a corrugated, water-resistant core sheet, The water repellency (JIS P8137) of at least one of both surfaces of the corrugated, water-resistant core sheet and the core sheet-side surface of the water-resistant linerboard in the recyclable water-resistant corrugated fiber board sheet is at least R 6 and the Cobb water absorption (JIS P8140; contact time: 30 minutes) of the surface of the corrugated fiberboard sheet is not higher than 30 gm2.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: September 21, 2004
    Assignee: Oji Paper Co., Ltd.
    Inventors: Masahiro Kumabe, Fumito Ogawa, Masaru Yamakoshi, Tatsuhiko Nishiyauchi
  • Publication number: 20030087065
    Abstract: The present invention provides a water-resistant corrugated fiberboard sheet having a high water resistance and capable of being recycled after the use.
    Type: Application
    Filed: June 27, 2002
    Publication date: May 8, 2003
    Applicant: OJI PAPER CO., LTD
    Inventors: Masahiro Kumabe, Fumito Ogawa, Masaru Yamakoshi, Tatsuhiko Nishiyauchi
  • Patent number: 5110915
    Abstract: A lignosellulose-phenolic compound composite product having a weight ratio of the lignocellulose material to the phenolic compound of 0.4/1.0 to 5.0/1.0 is prepared by heat-dissolving the lignocellulose material in a solvent comprising, as a main component, at least one phenolic compound, optionally in the presence of a dissolving acid catalyst, and then adjusting the amount of the phenolic compound to a level of 1/0.4 to 1/5.0 of the weight of the lignocellulose material, in which heat-dissolving step water generated, as a by-product, from the reaction of the lignocellulose material with the phenolic compound is preferably eliminated, to allow the temperature of the reaction system to rise and thus promote the heat-dissolving reaction.
    Type: Grant
    Filed: September 26, 1990
    Date of Patent: May 5, 1992
    Assignee: Oji Paper Co., Ltd.
    Inventors: Naohiko Tsujimoto, Masaru Yamakoshi, Toshimitsu Kudo, Yukiko Horiuchi, Jiro Shimizu