Patents by Inventor Masashi Nakatsuka

Masashi Nakatsuka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • WT1 substitution peptides
    Patent number: 7378384
    Abstract: Novel substituted type peptides of WT1 wherein the cysteine residue is substituted with a defined amino acid residue, polynucleotides encoding said peptides, cancer vaccines using those peptides or polynucleotides in vivo or in vitro, or the like are provided. Peptides which comprise an amino acid sequence of the formula: X-Y-Thr-Trp-Asn-Gln-Met-Asn-Leu (SEQ ID NO: 4) wherein X represents Ser, Ala, Abu, Arg, Lys, Orn, Cit, Leu, Phe, or Asn, and Y represents Tyr or Met, and which has an activity to induce CTLs, polynucleotides encoding said peptides, cancer vaccines which comprise those peptides or polynucleotides as an active ingredient, and the like are disclosed.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: May 27, 2008
    Assignees: International Institute of Cancer Immunology, Inc., Chugai Seiyaku Kabushiki Kaisha, Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Haruo Sugiyama, Masashi Gotoh, Hideo Takasu, Fumio Samizo, Naoto Kusunose, Masashi Nakatsuka
  • Wt1 substitution pepides
    Publication number: 20060205667
    Abstract: Novel substituted type peptides of WT1 wherein the cysteine residue is substituted with a defined amino acid residue, polynucleotides encoding said peptides, cancer vaccines using those peptides or polynucleotides in vivo or in vitro, or the like are provided. Peptides which comprise an amino acid sequence of the formula: X—Y-Thr-Trp-Asn-Gln-Met-Asn-Leu (SEQ ID NO: 4) wherein X represents Ser, Ala, Abu, Arg, Lys, Orn, Cit, Leu, Phe, or Asn, and Y represents Tyr or Met, and which has an activity to induce CTLs, polynucleotides encoding said peptides, cancer vaccines which comprise those peptides or polynucleotides as an active ingredient, and the like are disclosed.
    Type: Application
    Filed: September 19, 2003
    Publication date: September 14, 2006
    Inventors: Haruo Sugiyama, Masashi Gotoh, Hideo Takasu, Fumio Samizo, Naoto Kusunose, Masashi Nakatsuka
  • Hydroxamic acid derivatives
    Patent number: 6713477
    Abstract: A hydroxamic acid derivative represented by formula (1) or a prodrug thereof, or a pharmaceutically acceptable salt thereof, which has a matrix metalo-proteinase inhibitor.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: March 30, 2004
    Assignee: Sumitomo Pharmaceuticals Company, Limited
    Inventors: Gerard Robert Scarlato, Sara Sabina Hadida Ruah, Tamiki Nishimura, Masashi Nakatsuka, Fumio Samizo, Yumiko Kamikawa, Hitoshi Houtigai
  • Isoxazole derivatives
    Patent number: 6100260
    Abstract: An isoxazole derivative represented by the formula: ##STR1## or a pharmaceutically acceptable salt thereof useful as a therapeutic drug for auto-immune diseases and inflammatory diseases.
    Type: Grant
    Filed: April 20, 1998
    Date of Patent: August 8, 2000
    Assignee: Sumitomo Pharmaceutical Company, Limited
    Inventors: Masashi Nakatsuka, Yoshihide Ueno, Shin-ichiro Okada, Fumio Nishikaku
  • Phenylserine derivatives and processes for preparing the same
    Patent number: 4695580
    Abstract: Novel phenylserine derivatives of the formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof, pharmaceutical compositions, and a process for preparing the compounds are disclosed. The phenylserine derivatives and pharmaceutically acceptable acid addition salts are capable of inhibiting the biosynthesis of leucotrienes and/or antagonistic activity against SRS-A and hence are useful for prophylaxis and treatment of various allergic diseases (e.g. bronchial asthma, allergic nasitis, urticaria), ischemic heart diseases, ischemic encephalopathy, inflammation, or the like.
    Type: Grant
    Filed: December 19, 1984
    Date of Patent: September 22, 1987
    Assignee: Sumitomo Pharmaceuticals Company, Ltd.
    Inventors: Naohito Ohashi, Shoji Nagata, Masashi Nakatsuka, Kikuo Ishizumi, Junki Katsube, Shunji Aono, Teruo Sakurama