Patents by Inventor Masashi Tsukada
Masashi Tsukada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230111211Abstract: A seat provided in a moving body includes: at least one piezoelectric sensor including a first surface located on a side of a body of a sitter and a second surface located opposite the first surface, the piezoelectric sensor configured to sense heartbeat-induced body vibrations of the sitter through the first surface; and at least one supporting member disposed inside a recess which is formed in at least one of a seating surface of the seat and a back surface of the seat, the supporting member supporting the piezoelectric sensor under the second surface of the piezoelectric sensor. A gap is provided in at least part of an area between a surface of the supporting member and an inner wall of the recess so that the surface of the supporting member and the inner wall of the recess do not come into contact with each other.Type: ApplicationFiled: September 21, 2022Publication date: April 13, 2023Applicant: TOYOTA BOSHOKU KABUSHIKI KAISHAInventors: Masashi TSUKADA, Wataru HAYASHI, Koji KANEDA
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Publication number: 20220306996Abstract: The present invention provides a mutant FAD-dependent glucose dehydrogenase comprising: a catalytic subunit; an electron transfer subunit; and a hitchhiker subunit; wherein each of the amino acid sequence of the catalytic subunit and the amino acid sequence of the electron transfer subunit comprises a cysteine residue introduced therein, the catalytic subunit and the electron transfer subunit being bound to each other through a disulfide bond between the cysteine residues to achieve improved thermal stability of the FAD-dependent glucose dehydrogenase.Type: ApplicationFiled: October 21, 2021Publication date: September 29, 2022Applicants: The University of North Carolina at Chapel Hill, ARKRAY, Inc.Inventors: Koji Sode, Junko Shimazaki, Katsuhiro Kojima, Masashi Tsukada
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Patent number: 11293921Abstract: A molecular recognition element comprising a target molecule-recognizing portion, and a direct electron transfer-type oxidoreductase linked to the target molecule-recognizing portion.Type: GrantFiled: October 2, 2019Date of Patent: April 5, 2022Assignees: ARKRAY, Inc., Ultizyme International Ltd.Inventors: Koji Sode, Yuka Takahashi, Junko Shimazaki, Masashi Tsukada, Yosuke Murase
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Publication number: 20200110080Abstract: A molecular recognition element comprising a target molecule-recognizing portion, and a direct electron transfer-type oxidoreductase linked to the target molecule-recognizing portion.Type: ApplicationFiled: October 2, 2019Publication date: April 9, 2020Applicants: ARKRAY, Inc., Ultizyme International Ltd.Inventors: Koji Sode, Yuka Takahashi, Junko Shimazaki, Masashi Tsukada, Yosuke Murase
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Patent number: 9588210Abstract: Provided is an analysis apparatus capable of acquiring a measurement result with high reliability that includes: a signal detection unit; a measuring unit; a first temperature detection unit; a second temperature detection unit; and a calculation unit.Type: GrantFiled: February 1, 2011Date of Patent: March 7, 2017Assignee: ARKRAY, Inc.Inventors: Masashi Tsukada, Yasuhide Kusaka
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Publication number: 20150276652Abstract: An analysis device is disclosed which includes an electron detection medium to obtain information needed for analyzing an analyte in correlation with an electron transfer level, and a reagent part which is disposed on the electron detection medium and includes an electron transporting substance to transport electrons between the analyte and the electron detection medium, the electron transporting substance including a water-soluble aromatic heterocycle compound, and being free of a metal complex. An analysis method using the analysis device is also disclosed.Type: ApplicationFiled: April 14, 2015Publication date: October 1, 2015Applicant: ARKRAY, INC.Inventor: Masashi Tsukada
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Patent number: 9045790Abstract: An analysis device is disclosed which includes an electron detection medium to obtain information needed for analyzing an analyte in correlation with an electron transfer level, and a reagent part which is disposed on the electron detection medium and includes an electron transporting substance to transport electrons between the analyte and the electron detection medium, the electron transporting substance including a water-soluble aromatic heterocycle compound, and being free of a metal complex. An analysis method using the analysis device is also disclosed.Type: GrantFiled: April 25, 2012Date of Patent: June 2, 2015Assignee: ARKRAY, Inc.Inventor: Masashi Tsukada
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Publication number: 20150129425Abstract: An enzyme electrode includes an electrode, and a detection layer that is in contact with the electrode and includes an oxidoreductase, a water-soluble conductive polymer, and conductive particles, electrons being transferred between the enzyme and the electrode by direct electron transfer in the detection layer.Type: ApplicationFiled: June 25, 2013Publication date: May 14, 2015Applicant: BIOENGINEERING LABORATORIES, LLCInventors: Masashi Tsukada, Mayumi Tajima
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Patent number: 8858768Abstract: The present invention provides an electrochemical sensor comprising a substrate, an electrically conductive layer made of carbon particles which is disposed on the substrate, a cell membrane mimetic structure layer containing an enzyme at least one of inside the cell membrane mimetic structure layer and on the interface of the cell membrane mimetic structure layer which is disposed on the electrically conductive layer.Type: GrantFiled: February 4, 2010Date of Patent: October 14, 2014Assignee: ARKRAY, Inc.Inventors: Koji Katsuki, Yoshiaki Fujinawa, Masashi Tsukada, Yosuke Murase
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Publication number: 20130197847Abstract: Provided is an analysis apparatus capable of acquiring a measurement result with high reliability that includes: a signal detection unit; a measuring unit; a first temperature detection unit; a second temperature detection unit; and a calculation unit.Type: ApplicationFiled: February 1, 2011Publication date: August 1, 2013Applicant: ARKRAY, Inc.Inventors: Masashi Tsukada, Yasuhide Kusaka
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Publication number: 20130123594Abstract: Depletion of an analyte on a surface of an electrode is restrained by increasing a quantity of supply of the analyte to the surface of the electrode. An electrochemical sensor includes a substrate, an electrode provided on the substrate, an external layer film provided on the substrate to cover the electrode, and a groove formed in at least a part of the substrate in a direction of the electrode of the substrate.Type: ApplicationFiled: March 3, 2011Publication date: May 16, 2013Applicant: ARKRAY, Inc.Inventor: Masashi Tsukada
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Publication number: 20120273368Abstract: An analysis device is disclosed which includes an electron detection medium to obtain information needed for analyzing an analyte in correlation with an electron transfer level, and a reagent part which is disposed on the electron detection medium and includes an electron transporting substance to transport electrons between the analyte and the electron detection medium, the electron transporting substance including a water-soluble aromatic heterocycle compound, and being free of a metal complex. An analysis method using the analysis device is also disclosed.Type: ApplicationFiled: April 25, 2012Publication date: November 1, 2012Inventor: Masashi Tsukada
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Publication number: 20120259192Abstract: Provided are a measurement device, a sensor unit, and a sensor placement method, which enable the suppression of the occurrence of a situation where a measurement carried out with a sensor implanted under the skin, the implanted sensor becomes faulty. A sensor unit is used for measuring numerical information relating to a substance contained in a body fluid in a body. The sensor unit is provided with a sensor a part of which is placed under the skin and generates a signal according to the state of the substance, a base which is disposed on the skin and holds the sensor, a variable mechanism which is attached to the base and enables the position and/or the direction of the sensor with reference to the base to be varied, and an external terminal which is provided in the base and leads the signal generated by the sensor to the outside.Type: ApplicationFiled: November 25, 2010Publication date: October 11, 2012Applicant: ARKRAY, INC.Inventors: Masashi Tsukada, Yasuhide Kusaka, Akihiro Yamamoto
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Publication number: 20120116706Abstract: Provided is an analysis device or an analysis method, by which highly reliable analysis results can be obtained even in the circumstances where environment temperature changes, while reducing load on the user. The analysis device (1) is provided with a determining means (13) which determines whether environmental temperature measured by means of a temperature measuring means (6) is within a predetermined temperature range or not. The determining means (13) is so configured as to determine whether the environmental temperature is within the predetermined temperature range or not, even in the circumstances where information relating to a target substance in a sample cannot be obtained from the analysis device.Type: ApplicationFiled: June 25, 2010Publication date: May 10, 2012Applicant: ARKRAY, Inc.Inventors: Hiroyuki Nakanishi, Yoshiharu Uehata, Masako Kawanishi, Yosuke Murase, Masashi Tsukada
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Publication number: 20120029332Abstract: Analysis equipment is provided, which is capable of fulfilling a demand for miniaturization and ensuring high sensitivity, and which can be produced easily. The present invention relates to a method of continuously measuring a substrate concentration based on a response when a voltage is applied to a sensor. The present invention includes a response voltage application step of applying a response voltage E2 at which a response attributed to a substrate is obtained and a non-response voltage application step of applying a non-response voltage E1 at which the response attributed to the substrate is not obtained or is not substantially obtained. Preferably, the response voltage application step and the non-response voltage application step are repeated alternately.Type: ApplicationFiled: March 15, 2010Publication date: February 2, 2012Applicant: ARKRAY, IncInventors: Koji Katsuki, Masashi Tsukada
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Publication number: 20110308944Abstract: The present invention provides an electrochemical sensor comprising a substrate, an electrically conductive layer made of carbon particles which is disposed on the substrate, a cell membrane mimetic structure layer containing an enzyme at least one of inside the cell membrane mimetic structure layer and on the interface of the cell membrane mimetic structure layer which is disposed on the electrically conductive layer.Type: ApplicationFiled: February 4, 2010Publication date: December 22, 2011Applicant: ARKRAY, Inc.Inventors: Koji Katsuki, Yoshiaki Fujinawa, Masashi Tsukada, Yosuke Murase
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Patent number: 7776575Abstract: A mutant glucose dehydrogenase having the amino acid sequence of SEQ ID NO: 3 or an amino acid sequence of SEQ ID NO: 3 including substitution, deletion, insertion or addition of one or more amino acid residues other than the amino acid residue at the 365th position and having glucose dehydrogenase activity, wherein an amino acid residue at a position corresponding to the 365th position of the amino acid sequence is replaced with another amino acid residue, and the mutant glucose dehydrogenase shows an improved substrate specificity to glucose.Type: GrantFiled: September 9, 2009Date of Patent: August 17, 2010Assignee: Arkray, Inc.Inventors: Hideaki Yamoaka, Masashi Tsukada
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Publication number: 20100086989Abstract: A mutant glucose dehydrogenase having the amino acid sequence of SEQ ID NO: 3 or an amino acid sequence of SEQ ID NO: 3 including substitution, deletion, insertion or addition of one or more amino acid residues other than the amino acid residue at the 365th position and having glucose dehydrogenase activity, wherein an amino acid residue at a position corresponding to the 365th position of, the amino acid sequence is replaced with another amino acid residue, and the mutant glucose dehydrogenase shows an improved substrate specificity to glucose.Type: ApplicationFiled: September 9, 2009Publication date: April 8, 2010Applicant: Arkray, Inc.Inventors: Hideaki Yamaoka, Masashi Tsukada
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Patent number: 7604969Abstract: A mutant glucose dehydrogenase having an improved substrate specificity to glucose, which is a protein comprising the amino acid sequence depicted in SEQ ID NO:3 or an amino acid sequence having the substitution, deletion, insertion or addition of one or more amino acid residues excluding amino acid 365 in the amino acid sequence depicted in SEQ ID NO:3 and having a glucose dehydrogenase activity, the amino acid residue corresponding to amino acid 365 being substituted by other amino acid residue.Type: GrantFiled: June 12, 2006Date of Patent: October 20, 2009Assignee: Arkray, Inc.Inventors: Hideaki Yamaoka, Masashi Tsukada
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Publication number: 20080206833Abstract: A mutant glucose dehydrogenase having an improved substrate specificity to glucose, which is a protein comprising the amino acid sequence depicted in SEQ ID NO:3 or an amino acid sequence having the substitution, deletion, insertion or addition of one or more amino acid residues excluding amino acid 365 in the amino acid sequence depicted in SEQ ID NO:3 and having a glucose dehydrogenase activity, the amino acid residue corresponding to amino acid 365 being substituted by other amino acid residue.Type: ApplicationFiled: June 12, 2006Publication date: August 28, 2008Applicant: ARKRAY, INC.Inventors: Hideaki Yamaoka, Masashi Tsukada