Patents by Inventor Masato Horikawa
Masato Horikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220306985Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the likeType: ApplicationFiled: May 23, 2022Publication date: September 29, 2022Applicants: Nissan Chemical Industries, Ltd., Kyoto UniversityInventors: Taito NISHINO, Tatsuro KANAKI, Ayako OTANI, Koichiro SARUHASHI, Misayo Tomura, Takehisa IWAMA, Masato HORIKAWA, Norio NAKATSUJI, Tomomi OTSUJI
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Patent number: 11371013Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like.Type: GrantFiled: February 26, 2020Date of Patent: June 28, 2022Assignees: Nissan Chemical Industries, Ltd., Kyoto UniversityInventors: Taito Nishino, Tatsuro Kanaki, Ayako Otani, Koichiro Saruhashi, Misayo Tomura, Takehisa Iwama, Masato Horikawa, Norio Nakatsuji, Tomomi Otsuji
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Publication number: 20200208101Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the likeType: ApplicationFiled: February 26, 2020Publication date: July 2, 2020Applicants: Nissan Chemical Industries, Ltd., Kyoto UniversityInventors: Taito NISHINO, Tatsuro KANAKI, Ayako OTANI, Koichiro SARUHASHI, Misayo Tomura, Takehisa IWAMA, Masato HORIKAWA, Norio NAKATSUJI, Tomomi OTSUJI
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Patent number: 10590380Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like.Type: GrantFiled: March 2, 2017Date of Patent: March 17, 2020Assignees: Nissan Chemical Industries, Ltd., Kyoto UniversityInventors: Taito Nishino, Tatsuro Kanaki, Ayako Otani, Koichiro Saruhashi, Misayo Tomura, Takehisa Iwama, Masato Horikawa, Norio Nakatsuji, Tomomi Otsuji
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Patent number: 10316292Abstract: A culture method (a preservation method) of somatic stem cells does not use a chemical such as DMSO that affects a differentiation function of somatic stem cells. A material for an undifferentiated state-maintaining culture for a somatic stem cell, having a naturally occurring polysaccharide; a culture liquid in which the material for the undifferentiated state-maintaining culture is dispersed; a somatic stem cell-containing culture liquid in which the somatic stem cell is suspended in the culture liquid; and a culture method for mesenchymal stem cells in which a naturally occurring polysaccharide is used.Type: GrantFiled: January 23, 2015Date of Patent: June 11, 2019Assignees: NISSAN CHEMICAL INDUSTRIES, LTD., KYUSHU UNIVERSITYInventors: Satoru Kidoaki, Yukie Tuji, Hisato Hayashi, Takehisa Iwama, Masato Horikawa
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Patent number: 10017805Abstract: The present invention relates to a protein production accelerating agent that has enabled to largely increase the produced amount of a desired protein by adding polysaccharides to a medium for animal cells containing a serum or serum alternative, and a production method of a protein using a medium containing the protein production accelerating agent.Type: GrantFiled: August 23, 2013Date of Patent: July 10, 2018Assignees: Nissan Chemical Industries, Ltd., Institute of National Colleges of Tehcnology, JapanInventors: Misayo Tomura, Takehisa Iwama, Koichiro Saruhashi, Taito Nishino, Masato Horikawa, Hiroharu Kawahara
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Publication number: 20170175077Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the likeType: ApplicationFiled: March 2, 2017Publication date: June 22, 2017Applicants: Nissan Chemical Industries, Ltd., Kyoto UniversityInventors: Taito NISHINO, Tatsuro KANAKI, Ayako OTANI, Koichiro SARUHASHI, Misayo Tomura, Takehisa IWAMA, Masato HORIKAWA, Norio NAKATSUJI, Tomomi OTSUJI
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Patent number: 9664671Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like.Type: GrantFiled: July 24, 2013Date of Patent: May 30, 2017Assignees: Nissan Chemical Industries, Ltd., Kyoto UniversityInventors: Taito Nishino, Tatsuro Kanaki, Ayako Otani, Koichiro Saruhashi, Misayo Tomura, Takehisa Iwama, Masato Horikawa, Norio Nakatsuji, Tomomi Otsuji
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Publication number: 20170009209Abstract: A culture method (a preservation method) of somatic stem cells does not use a chemical such as DMSO that affects a differentiation function of somatic stem cells. A material for an undifferentiated state-maintaining culture for a somatic stem cell, having a naturally occurring polysaccharide; a culture liquid in which the material for the undifferentiated state-maintaining culture is dispersed; a somatic stem cell-containing culture liquid in which the somatic stem cell is suspended in the culture liquid; and a culture method for mesenchymal stem cells in which a naturally occurring polysaccharide is used.Type: ApplicationFiled: January 23, 2015Publication date: January 12, 2017Applicants: NISSAN CHEMICAL INDUSTRIES, LTD., KYUSHU UNIVERSITYInventors: Satoru KIDOAKI, Yukie TUJI, Hisato HAYASHI, Takehisa IWAMA, Masato HORIKAWA
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Publication number: 20140162318Abstract: [Summary] The present invention relates to a protein production accelerating agent that has enabled to largely increase the produced amount of a desired protein by adding polysaccharides to a medium for animal cells containing a serum or serum alternative, and a production method of a protein using a medium containing the protein production accelerating agent.Type: ApplicationFiled: August 23, 2013Publication date: June 12, 2014Applicants: Institute of National Colleges of Technology, Japan, Nissan Chemical Industries, Ltd.Inventors: Misayo TOMURA, Takehisa IWAMA, Koichiro SARUHASHI, Taito NISHINO, Masato HORIKAWA, Hiroharu KAWAHARA
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Publication number: 20140106348Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like.Type: ApplicationFiled: July 24, 2013Publication date: April 17, 2014Inventors: Taito NISHINO, Tatsuro KANAKI, Ayako OTANI, Koichiro SARUHASHI, Misayo Tomura, Takehisa IWAMA, Masato HORIKAWA, Norio NAKATSUJI, Tomomi OTSUJI
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Patent number: 8440666Abstract: Novel pyridazinone compounds of formula (I), which inhibit the purinergic P2X7 receptor and are useful for prevention, therapy and improvement of inflammatory and immunological diseases.Type: GrantFiled: October 30, 2008Date of Patent: May 14, 2013Assignee: Nissan Chemical Industries, Ltd.Inventors: Yukihiro Shigeta, Yutaka Hirokawa, Hiroshi Nagai, Kei Nagae, Tsuneo Watanabe, Megumi Io, Yusuke Shintani, Junji Kamon, Masato Horikawa, Kazuya Takeuchi
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Patent number: 8134013Abstract: The present invention provides compounds useful for prevention, treatment or alleviation of diseases against which activation of the thrombopoietin receptor is effective. A compound represented by the formula (1): wherein A, B, R1, L1, R2, L2, L3, Y, L4, R3 and X are the same as defined in the description, a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: GrantFiled: December 14, 2005Date of Patent: March 13, 2012Assignee: Nissan Chemical Industries, Ltd.Inventors: Katsuaki Myaji, Shunsuke Iwamoto, Satoshi Nakano, Hirofumi Ota, Yukihiro Shigeta, Yutaka Hirokawa, Kazufumi Yanagihara, Koji Toyama, Shingo Owada, Masato Horikawa, Norihisa Ishiwata
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Patent number: 7968542Abstract: A compound represented by the formula (I) (wherein R1, R2, R3 and R4 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: GrantFiled: July 13, 2006Date of Patent: June 28, 2011Assignee: Nissan Chemical Industries, Ltd.Inventors: Katsuaki Miyaji, Kazufumi Yanagihara, Yukihiro Shigeta, Shunsuke Iwamoto, Masato Horikawa, Yutaka Hirokawa, Shingo Owada, Satoshi Nakano, Hirofumi Ota, Norihisa Ishiwata
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Patent number: 7960425Abstract: A compound represented by the formula (I) (wherein R1, R2, R3 and R4 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: GrantFiled: July 19, 2006Date of Patent: June 14, 2011Assignee: Nissan Chemical Industries, Ltd.Inventors: Katsuaki Miyaji, Yutaka Hirokawa, Masato Horikawa, Norihisa Ishiwata
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Publication number: 20110092496Abstract: A compound represented by the formula (I) (wherein R1, R2, R3 and R4 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: November 29, 2010Publication date: April 21, 2011Applicant: Nissan Chemical Industries, Ltd.Inventors: Katsuaki MIYAJI, Kazufumi Yanagihara, Yukihiro Shigeta, Shunsuke Iwamoto, Masato Horikawa, Yutaka Hirokawa, Shingo Owada, Satoshi Nakano, Hirofumi Ota, Norihisa Ishiwata
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Publication number: 20100286390Abstract: Novel pyridazinone compounds of formula (I), which inhibit the purinergic P2X7 receptor and are useful for prevention, therapy and improvement of inflammatory and immunological diseases.Type: ApplicationFiled: October 30, 2008Publication date: November 11, 2010Inventors: Yukihiro Shigeta, Yutaka Hirokawa, Hiroshi Nagai, Kei Nagae, Tsuneo Watanabe, Megumi Io, Yusuke Shintani, Junji Kamon, Masato Horikawa, Kazuya Takeuchi
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Publication number: 20090131659Abstract: The present invention provides compounds useful for prevention, treatment or alleviation of diseases against which activation of the thrombopoietin receptor is effective. A compound represented by the formula (1): wherein A, B, R1, L1, R2, L2, L3, Y, L4, R3 and X are the same as defined in the description, a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: December 14, 2005Publication date: May 21, 2009Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Katsuaki Miyaji, Shunsuke Iwamoto, Satoshi Nakano, Hirofumi Ota, Yukihiro Shigeta, Yutaka Hirokawa, Kazufumi Yanagihara, Koji Toyama, Shingo Owada, Masato Horikawa, Norihisa Ishiwata
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Publication number: 20090131676Abstract: A compound represented by the formula (I) (wherein R1, R2, R3 and R4 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: July 19, 2006Publication date: May 21, 2009Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Katsuaki Miyaji, Yutaka Hirokawa, Masato Horikawa, Norihisa Ishiwata
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Publication number: 20090118500Abstract: A compound represented by the formula (I) (wherein R1, R2, R3 and R4 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.Type: ApplicationFiled: July 13, 2006Publication date: May 7, 2009Applicant: NISSAN CHEMICAL INDUSTRIES, LTDInventors: Katsuaki Miyaji, Kazufumi Yanagihara, Yukihiro Shigeta, Shunsuke Iwamoto, Masato Horikawa, Yutaka Hirokawa, Shingo Owada, Satoshi Nakano, Hirofumi Ota, Norihisa Ishiwata