Abstract: A component-embedded substrate includes: a plurality of insulating layers each including a wiring pattern formed on one surface; an embedded component including a connection terminal; and a plurality of vias that electrically connect the connection terminal to the wiring patterns adjacent to each other in a lamination direction. The plurality of insulating layers is laminated on the connection terminal. Each of the plurality of vias is composed of a via hole formed in the respective insulating layer of the plurality of the insulating layers and a conductive material provided in the via hole. One of the plurality of vias is a connection via directly connected to the connection terminal. Another of the plurality of vias is a first adjacent via adjacent to the connection via in the lamination direction. The first adjacent via is connected to the wiring pattern formed on a surface of a top insulating layer.

Abstract: A cartridge detachably mountable to a main assembly of an electrophotographic image forming apparatus, the cartridge includes (i) a rotatable developing roller for developing a latent image formed on a photosensitive member; (ii) a first drive transmission member capable of receiving a rotational force originated by the main assembly; (iii) a second drive transmission member capable of coupling with the first drive transmission member and capable of transmitting the rotational force received by the first drive transmission member to the developing roller; and (iv) a coupling disconnection member including a force receiving portion capable of receiving the force originated by the main assembly, and an urging portion capable of urging at least one of the first drive transmission member and the second drive transmission member by the force received by the force receiving portion to separate one of the first drive transmission member and the second drive transmission member from the other, thereby disconnecting t

Abstract: An image forming apparatus, having a main housing, a first photosensitive drum, a second photosensitive drum, a first developing device to supply toner to the first photosensitive drum, a second developing device to supply toner to the second photosensitive drum, a first reloading device to reload the first developing device with the toner, and a second reloading device to reload the second developing device with the toner, is provided. The first reloading device has a first reloading port, which accepts the toner for reloading the first developing device. The first reloading port is openable to an outside of the main housing. The second reloading device has a second reloading port, which accepts the toner for reloading the second developing device. The second reloading port is openable to the outside of the main housing.

Abstract: An object of the present invention is to provide a novel resin that is useful as a film forming material for lithography and the like. The problem can be solved by a resin containing a constituent unit represented by the following formula (1) or (1)?: wherein the variables in the formulas are as described in the specification.

Abstract: The present invention provides a novel method which makes it possible to obtain, from a piece of tissue, a sample enriched with cells or cell nuclei of interest. A piece of tissue is subjected to pretreatment comprising water flow disruption and/or ultrasonic disruption to obtain a population of particles including individually separated cells or cell nuclei. A population of particles significantly abundant in cells or cell nuclei of interest is sorted or fractionated on the basis of optical properties of the cell nuclei in the separated cells or of the separated cell nuclei or on the basis of physical properties of the cell nuclei in the separated cells or of the separated cell nuclei.

Abstract: A cartridge detachably mountable to a main assembly of an electrophotographic image forming apparatus, the cartridge includes (i) a rotatable developing roller for developing a latent image formed on a photosensitive member; (ii) a first drive transmission member capable of receiving a rotational force originated by the main assembly; (iii) a second drive transmission member capable of coupling with the first drive transmission member and capable of transmitting the rotational force received by the first drive transmission member to the developing roller; and (iv) a coupling disconnection member including a force receiving portion capable of receiving the force originated by the main assembly, and an urging portion capable of urging at least one of the first drive transmission member and the second drive transmission member by the force received by the force receiving portion to separate one of the first drive transmission member and the second drive transmission member from the other, thereby disconnecting t

Abstract: A fiber laser device includes a first optical fiber, a second optical fiber, and a third optical fiber configured by polarization maintaining fibers. The first optical fiber includes at least one first part and at least two second parts alternatively disposed with the first part. The first part and the second part adjacent to each other are connected to each other such that a fast axis of the first part coincides with a slow axis of the second part at a connection point. A total length of the first part is equal to a total length of the second parts. A mode field diameter of the first optical fiber is smaller than each of a mode field diameter of the second optical fiber and a mode field diameter of the third optical fiber.

Abstract: A tissue-fastening tool indwelling system includes: a sheath; a needle tube disposed in the sheath; a tissue-fastening tool including a wire having a coil region disposable in the needle tube in a stretched state and restorable to a coil shape with the same winding diameter outside the needle tube; a stylet connected to the wire; and a manipulation part for manipulating the stylet to advance the wire and rotate the sheath in a first direction. In a state where a distal end of the needle tube is proximal of the distal end of the sheath, the manipulation part is designed to operate such that the wire is delivered from the sheath by a length of one winding of the coil region per rotation of the sheath by less than one turn, and the protruding coil region biased to have a diameter larger than the winding diameter.

Abstract: A needle holder for holding a curved needle to which a suture thread is connected. The needle holder includes a flexible tube; and a grasper provided at a distal end of the flexible tube. The grasper includes a first jaw having a groove, and a protrusion at a distal end portion of the first jaw; and a second jaw movably connected to the first jaw. The grasper can hold the curved needle between the second jaw and the protrusion of the first jaw, and can hold a part of the suture thread between a surface of the groove and the second jaw such that another part of the suture thread passes through a gap formed between another surface of the groove and the second jaw. The protrusion has a hook surface for hooking the suture thread extending outside the groove.

Abstract: A tissue-fastening tool indwelling system includes: a sheath; a needle tube disposed in the sheath; a tissue-fastening tool including a wire having a coil region disposable in the needle tube in a stretched state and restorable to a coil shape with the same winding diameter outside the needle tube; a stylet connected to the wire; and a manipulation part for manipulating the stylet to advance the wire and rotate the sheath in a first direction. In a state where a distal end of the needle tube is proximal of the distal end of the sheath, the manipulation part is designed to operate such that the wire is delivered from the sheath by a length of one winding of the coil region per rotation of the sheath by less than one turn, and the protruding coil region biased to have a diameter larger than the winding diameter.

Abstract: An endoscopic treatment tool includes: a needle tube in which a needle tube insertion passage extending from a distal end to a proximal end of the needle tube is formed; a stylet which is disposed to move freely in the needle tube insertion passage; a main manipulation part which is connected to a proximal end side of the needle tube, the main manipulation part supporting the stylet such that the stylet advances while rotating, and the main manipulation part operating the stylet; a manipulation transmission member which has flexibility and the manipulation transmission member is connected to the stylet; and an auxiliary manipulation part which includes a handle fixed to a proximal end portion of the manipulation transmission member and the auxiliary manipulation part is configured such that the manipulation transmission member advances while rotating in accordance with a manipulation of the handle.

Abstract: A molded foam member manufacturing method including: a first process of placing a foam molded first portion and a rigid member in a second portion forming mold, and pressing and fixing the rigid member against the second portion forming mold; and a second process of pouring a second portion-forming synthetic resin raw material into the second portion forming mold and foam molding a second portion so as to surround at least a portion of the rigid member and to form an integral unit with the first portion.

Abstract: A tissue-fastening tool indwelling device includes: a sheath; a needle tube having a needle tip and disposed to be retractable from a distal end of a lumen of the sheath; a tissue-fastening tool having a restoring force to a curved shape with distal and proximal end side regions and disposed inside the needle tube in a stretched state; and a stylet coupled to a proximal end portion of the tissue-fastening tool in the needle tube. The stylet has a first state in which the stylet is advanced straight with respect to the needle tube and the sheath until the entire distal end side region of the tissue-fastening tool protrudes from the needle tube, and a second state in which the stylet is advanced while being rotated until a proximal end of the proximal end side region of the tissue-fastening tool protrudes from the needle tube.

Abstract: An endoscopic treatment tool set includes: an endoscopic treatment tool that includes a sheath having a lumen, an elongated shaft inserted into the lumen and the elongated shaft having an insertion passage, a stylet disposed in the insertion passage, an implant connected to the stylet, and a manipulation part provided at the sheath; and a jig. The endoscopic treatment tool is packed together with the jig. The jig is coupled to a proximal end portion of the stylet disposed in the manipulation part and the jig is configured to be movable relative to the manipulation part. The implant is connected to the jig via the stylet, and the implant is configured such that the jig is pulled toward a proximal end side of the manipulation part so that the stylet is moved to a proximal end side in the insertion passage and the implant is loaded in the insertion passage.

Abstract: An endoscopic treatment tool includes: a sheath in which a lumen is formed; a treatment part which is inserted into the lumen and is configured to protrude and retract from a distal end of the sheath; a main manipulation part which is connected to the proximal end side of the sheath and allows the treatment part to perform a first motion and a second motion; an auxiliary manipulation part which is disposed to be separate from the main manipulation part and is configured to perform the first motion of the treatment part and configured to put the second motion out of action; and a manipulation transmission member which is made of a flexible member, connects the auxiliary manipulation part to the main manipulation part, and transmits a manipulation input of the auxiliary manipulation part with respect to the main manipulation part.

Abstract: An endoscopic treatment tool includes a sheath having a lumen, an elongated shaft inserted into the lumen and having an insertion passage, a stylet disposed in the insertion passage, an implant connected to the stylet, and a manipulation part main body provided on the sheath, a slider advanceable and retractable in an axial direction relative to the manipulation part main body, and a cam tube retracting while rotating in accordance with manipulation of the slider and having a spiral guide passage. A proximal end portion of the stylet has a projection engaged with the guide passage such that a force retracting the stylet is applied to the stylet by the cam tube retracting while rotating. The projection is slidable on the guide passage such that the stylet is advanceable relative to the elongated shaft against the force.