Patents by Inventor Masayoshi Ito
Masayoshi Ito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5101026Abstract: The present invention relates to ganglioside related compounds having, for example, the following formula: ##STR1## where R.sub.1 represents H or COCH.sub.3 (hereinafter abbreviated to "AC"); R.sub.2 represents H or CH.sub.3 ; and R.sub.3 represents --OH, ##STR2## These ganglioside related compounds are useful as membrane receptors, tumor markers, cell growth controlling substances, etc., and useful for immunotherapy for cancer, etc.Type: GrantFiled: August 6, 1987Date of Patent: March 31, 1992Assignee: MECT CorporationInventors: Tomoya Ogawa, Mamoru Sugimoto, Masaaki Numata, Masayoshi Ito, Yoshiyasu Shitori, Shigeki Nunomura
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Patent number: 5061425Abstract: A process for producing a high modulus, high tenacity polyethylene terephthalate filament which comprises (1) spinning a solution of polyethylene terephthalate in an organic solvent through a die to produce a solution spun filament, wherein the polyethylene terephthalate has an intrinsic viscosity of at least about 1.0 dl/g and wherein the organic solvent is selected from the group consisting of (a) hexafluoroisopropanol, (b) trifluoroacetic acid, (c) mixed solvent systems containing from about 20 weight percent to about 99 weight percent hexafluoroisopropanol and from about 1 weight percent to about 80 weight percent dichloromethane, and (d) mixed solvent systems containing from about 20 weight percent to about 99 weight percent trifluoroacetic acid and from about 1 to about 80 weight percent dichloromethane; and (2) subsequently drawing the solution spun filament to a total draw ratio of at least about 7:1 to product the high modulus, high tenacity polyethylene terephthalate filament.Type: GrantFiled: September 7, 1989Date of Patent: October 29, 1991Assignee: The Goodyear Tire & Rubber CompanyInventors: Masayoshi Ito, Ming-Ya Tang, Soojaa L. Kim
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Patent number: 5057605Abstract: Sialocylglycerolipids represented by the following general formula (I): ##STR1## wherein R.sup.1 represents a hydrogen atom or a group CH.sub.3 CO--; R.sup.2 represents an alkali metal, a hydrogen atom or a lower alkyl group; R.sup.3 represents a hydrogen atom or a group C.sub.n H.sub.2n+1 -- (n is an integer ranging from 1 to 30); and R.sup.4 represents a group C.sub.m H.sub.2n+1 -- (m is an integer ranging from 1 to 30) are herein disclosed. They are prepared by treating a corresponding compound in an alkaline aqueous solvent. The method makes it possible to provide these compounds in a high yield by a simple processes.Type: GrantFiled: November 10, 1988Date of Patent: October 15, 1991Assignee: Mect CorporationInventors: Shoji Yoshimura, Yuzi Matsuzaki, Mamoru Sugimoto, Masayoshi Ito, Yoshiyasu Shitori, Tomoya Ogawa
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Patent number: 5055543Abstract: Disclosed herein is a one part moisture cure sealant which is cured under an ordinary temperature by reaction with moisture contained in the air. This sealant contains a cure accelerating catalyst of: ##STR1## in a sealing composite containing urethane prepolymer. Due to the action of this catalyst, not only the cure rate is improved but difference in the cure rate between a low-temperature/low-humidity season and a high-temperature/high-humidity season is reduced. This sealant is also excellent in storage stability.Type: GrantFiled: May 23, 1989Date of Patent: October 8, 1991Assignee: Sunrise Meisei CorporationInventors: Yoshinori Nakano, Kyohisa Kotsuma, Masayoshi Ito
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Patent number: 5023239Abstract: The present invention relates to a sodium salt of sialosyl cholesterol. The present compound has an excellent high water solubility, and therefore the compound is very useful as a medicine to be used for curing various diseases derived from lesions of peripheral or central nerves.Type: GrantFiled: January 7, 1988Date of Patent: June 11, 1991Assignee: MECT CorporationInventors: Haruo Ogura, Kimio Furuhata, Shingo Sato, Masayoshi Ito, Yoshiyasu Shitori, Yoshitaka Nagai
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Patent number: 5015631Abstract: A repairing agent for cells and tissues is disclosed, which agent comprises, as an active ingredient, a compound of the general formula: ##STR1## wherein Z represents lithium, potassium, sodium, ammonium or an organic ammonium when n is 1, and Z represents calcium, barium or magnesium when n is 2.Type: GrantFiled: June 24, 1988Date of Patent: May 14, 1991Assignee: MECT CorporationInventors: Sadanori Ogasawara, Kenji Abiko, Masayoshi Ito, Yoshiyasu Shitori
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Patent number: 4990603Abstract: The present invention relates to sialic acid derivatives. According to the present invention, there is provided sialic acid derivatives having the general formula (I): ##STR1## wherein, R.sup.1 represents hydrogen, an acetyl group, a trityl group, ##STR2## (R.sup.5 represents hydrogen or an acetyl group and R.sup.6 represents hydrogen, sodium or a methyl group).R.sup.2 represents hydrogen or an acetyl group,one of R.sup.3 and R.sup.4 represents ##STR3## (R.sup.7 represents a hydrogen atom or an acetyl group, R.sup.8 represents a hydrogen atom, an acetyl group or a benzyl group, R.sup.9 represents a hydrogen atom, an acetyl group, a benzyl group or ##STR4## wherein R.sup.10 represents a hydrogen atom or a benzoyl group), while the other represents --COOR.sup.11 wherein R.sup.11 represents hydrogen, sodium, or a methyl group.Type: GrantFiled: June 30, 1987Date of Patent: February 5, 1991Assignee: Mect CorporationInventors: Tomoya Ogawa, Mamoru Sugimoto, Masaaki Numata, Shoji Yoshimura, Masayoshi Ito, Yoshiyasu Shitori
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Patent number: 4985838Abstract: Driving and driven wheel velocities of a vehicle are detected by wheel velocity sensors, and a change in driven wheel velocities as a function of time is detected to obtain a driven wheel acceleration by the vehicle acceleration calculating section. A reference target torque is calculated on the basis of the driven wheel acceleration. A slip value of the driving wheels is calculated on the basis of the driving and driven wheel velocities, and a correction torque corresponding to the slip value is calculated every predetermined sampling time at TSn calculating section and TPn calculating section. The correction torque is substracted from the reference target torque to obtain a target engine torque. An engine output is controlled to obtain the target engine torque.Type: GrantFiled: April 18, 1989Date of Patent: January 15, 1991Assignee: Mitsubishi Jidosha Kogyo Kabushiki KaishaInventors: Masayuki Hashiguchi, Kiichi Yamada, Masayoshi Ito, Atsuhiro Kawano, Susumu Nishikawa, Takeshi Funakoshi, Shuji Ikeda
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Patent number: 4985836Abstract: A driving and driven wheel velocity are detected by wheel velocity sensors. A reference velocity is set on the basis of the driven wheel velocity. A slip value of the driving wheel on the basis of a difference between the driving wheel velocity and reference velocity. A target output torque of an engine is set in accordance with the slip value of the driving wheel. The target output torque is corrected in accordance with a lateral acceleration generated in a widthwise direction of the vehicle. An output of the engine is controlled to reach the corrected target output torque.Type: GrantFiled: April 18, 1989Date of Patent: January 15, 1991Assignee: Mitsubishi Jidosha Kogyo Kabushiki KaishaInventors: Masayuki Hashiguchi, Kiichi Yamada, Masayoshi Ito, Atsuhiro Kawano, Susumu Nishikawa, Takeshi Funakoshi, Shuji Ikeda
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Patent number: 4970650Abstract: A first slip value detecting section detects slip values of the driving wheels on the basis of differences between the outputs from a selected driving wheel velocity and a reference velocity. And a second slip value detecting section detects slip values of the driving wheels on the basis of differences between the outputs from a driving wheel velocity detecting section and the reference velocity. And an engine output is controlled in accordance with the slip values detected by the first slip value detecting section. And braking force is controlled in accordance with the slip values detected by the second slip value detecting section.Type: GrantFiled: April 18, 1989Date of Patent: November 13, 1990Assignee: Mitsubishi Jidosha Kogyo Kabushiki KaishaInventors: Masayuki Hashiguchi, Kiichi Yamada, Masayoshi Ito, Atsuhiro Kawano, Susumu Nishikawa, Takeshi Funakoshi, Shuji Ikeda
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Patent number: 4968786Abstract: Novel sialic acid derivatives and galactose derivatives which are useful intermediate for the synthesis of gangliosides. Methods for the production of the sialic acid and galactose derivatives. Methods for the production of ganglioside GM.sub.3.Type: GrantFiled: June 27, 1985Date of Patent: November 6, 1990Assignees: Rikagaku Kenkyusho, MECT CorporationInventors: Tomoya Ogawa, Mamoru Sugimoto, Yoshiyasu Shitori, Masayoshi Ito
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Patent number: 4968471Abstract: This invention discloses a process for producing a high modulus, high tenacity polyethylene terephthalate filament which comprises (1) spinning a solution of polyethylene terephthalate in an organic solvent through a die to produce a solution spun filament, wherein the polyethylene terephthalate has an intrinsic viscosity of at least about 3.Type: GrantFiled: September 12, 1988Date of Patent: November 6, 1990Assignee: The Goodyear Tire & Rubber CompanyInventors: Masayoshi Ito, Ming-Ya Tang, Soojaa L. Kim
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Patent number: 4963653Abstract: A sialic acid-bonded octapeptide represented by the following general formula (I): ##STR1## wherein R represents a hydrogen atom or an acetyl group; and R' represents a lower alkyl group, an aralkyl group, a hydrogen atom or an alkali metal atom, is herein disclosed. The peptide chain of the sialic acid-bonded octapeptide is constituted by 8 amino acid molecules on the C-terminus side of FTS and the compounds represented by formula (I) can be obtained by bonding sialic acid to the amino terminus of the peptide chain according to condensation. These octapeptides show excellent physiological activity comparable to FTS and a half life in blood longer than that of FTS and it is expected that the affinity of the peptide to lymphocytes is also enhanced. Thus they can effectively be used as medicines for treating the lowering and abnormality of functions of the thymus.Type: GrantFiled: June 28, 1989Date of Patent: October 16, 1990Assignees: Mect Corporation, Mitsui Toatsu Chemical, Inc.Inventors: Yoshitaka Nagai, Shohei Shibayama, Masaaki Numata, Shoji Yoshimura, Makoto Tanaka, Masayoshi Ito, Akira Awaya, Hisashi Kobayashi, Hayao Abe, Yusaku Ishizuka, Tomoya Ogawa
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Patent number: 4950818Abstract: A novel and useful method for treating and/or preventing ulcer in human beings is provided which comprises administering an effective amount of a pharmaceutical composition comprising at least one of the conjugated .gamma.-oxybutenolide compounds represented by the general formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are the same or different and represent hydrogen atoms, alkyl groups, hydroxyl groups, alkoxy groups, nitro groups, cyano groups or halogen atoms; and optionally at least one pharmaceutically acceptable carrier.Type: GrantFiled: June 21, 1989Date of Patent: August 21, 1990Assignee: Kuraray Company, Ltd.Inventors: Yoshin Tamai, Masahiro Torihara, Yoichi Kido, Johji Yamahara, Masayoshi Ito
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Patent number: 4950750Abstract: The present invention provides ganglioside-related compounds expressed by the following formula: ##STR1## (wherein R.sub.1 denotes a hydrogen atom or SiR.sub.3 R.sub.4 R.sub.5 (wherein R.sub.3 and R.sub.4 each denotes a methyl or phenyl group, and R.sub.5 denotes a tertiary butyl or dimethylphenylmethyl group), and R.sub.2 denotes a hydrogen atom, a trityl group, or ##STR2## (wherein M denotes an alkali metal atom)) and methods of producing the same. These ganglioside-related compounds are useful as markers for the early detection of cancer and in the immunotherapy for cancer.Type: GrantFiled: October 19, 1987Date of Patent: August 21, 1990Assignee: Mect CorporationInventors: Tomoya Ogawa, Masaaki Numata, Mamoru Sugimoto, Shohei Shibayama, Shoji Yoshimura, Masayoshi Ito, Yoshiyasu Shitori
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Patent number: 4926333Abstract: The slip values DVR, DVL of the right and left driving wheels are respectively detected. The left braking control means control the left driving wheel in accordance with a correction slip value DVFL of the left driving wheel calculated by the following equation on the basis of the slip values DVL, DVR and the coefficient KB set by the coefficient setting means.DVFL=KB.multidot.DVL+(1-KB).multidot.DVRThe right braking control means control the right driving wheel in accordance with a correction slip value DVFR of the right driving wheel calculated by the following equation on the basis of the slip values DVR, DVL and the coefficent KB:DVFR=KB.multidot.DVR+(1-KB).multidot.DVL.Type: GrantFiled: April 17, 1989Date of Patent: May 15, 1990Assignee: Mitsubishi Jidosha Kogyo Kabushiki KaishaInventors: Masayuki Hashiguchi, Kiichi Yamada, Masayoshi Ito, Atsuhiro Kawano, Susumu Nishikawa, Takeshi Funakoshi, Shuji Ikeda
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Patent number: 4921948Abstract: The present application discloses a new sialosyl glyceride having the following formula, which compound is useful as a remedy for nervous diseases, has an excellent compatability with the living bodies, and is easily producible. ##STR1## wherein R.sup.1 represents a hydrogen atom or XCH.sub.2 CO-- (X being a halogen atom), R.sup.2 represents an alkali metal, a hydrogen atom or a lower alkyl group, R.sup.3 represents a hydrogen atom or --CO(CH.sub.2)mCH.sub.3, R.sup.4 represents --CO(CH.sub.2)mCH.sub.3 amd m and n each represents a number of 0 to 30.Type: GrantFiled: March 6, 1989Date of Patent: May 1, 1990Assignee: Mect CorporationInventors: Shoji Yoshimura, Yuzi Matsuzaki, Mamoru Sugimoto, Masayoshi Ito, Tomoya Ogawa
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Patent number: 4918177Abstract: A sialic acid derivative having an active carbonyl group represented by the formula [I]: ##STR1## wherein R.sup.1 represents hydrogen or acetyl group; R.sup.2 represents hydrogen, a metal or a lower alkyl group; R.sup.3 represents hydrogen, hydroxyl group, or a residue removed hydrogen from an alcohol portion of an active ester; Ac represents acetyl group; and n is 1 to 20, respectively. This sialic acid derivative [I] can be utilized as a starting material for various complex having a sialic acid in the molecule since it has an active carbonyl group in the molecules so that it shows high reactivity.Type: GrantFiled: December 21, 1987Date of Patent: April 17, 1990Assignee: Mect CorporationInventors: Shoji Yoshimura, Shohei Shibayama, Masaaki Numata, Masayoshi Ito, Yoshiyasu Shitori, Tomoya Ogawa
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Patent number: 4914195Abstract: A new process for preparing halides of N-acetylneuraminic acids useful as an intermediate in preparing new N-acetylneuraminic acid derivatives having an excellent immunological activity is provided, which process comprises simultaneously acetylating and halogenating an esterified N-acetylneuraminic acid with the aid of an acetyl halide, and according to the process, the halides may be obtained in high yield of about 90%.Type: GrantFiled: November 26, 1984Date of Patent: April 3, 1990Assignee: MECT CorporationInventors: Haruo Ogura, Kimio Furuhata, Yoshiyasu Shitori, Masayoshi Ito
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Patent number: 4883439Abstract: A cathode ray tube fixturing device for position a face panel and a funnel during a frit sealing process. The device includes a cone holder for positioning a constricted portion of the funnel, and a movable abutting block which is adapted to abut against the panel and the funnel. A pivoting arm connects the cone holder with the movable abutting block, and at least one fixed abutting block is adapted to abut against the panel and the funnel and is located in opposed relationship with respect to the movable abutting block. When the funnel and the panel are mounted in the cone holder in assembled relation, their common centerline is vertical. In this assembled relation, the panel and funnel are urged against the fixed abutting block by the movable abutting block so that the seal from the panel to the funnel can be effectively produced and the fixturing device is reduced in weight.Type: GrantFiled: December 7, 1987Date of Patent: November 28, 1989Assignee: Sony CorporationInventors: Tatsurou Sakamoto, Masayoshi Ito, Yoshinori Yamano