Patents by Inventor Masayoshi Samejima

Masayoshi Samejima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Controlled release pharmaceutical preparation and method for producing the same
    Patent number: 5254347
    Abstract: Disclosed is a controlled release pharmaceutical preparation, comprising a core containing a pharmaceutically active ingredient, and a porous film of a hydrophobic polymeric substance or a hydrophobic polymeric substance and a hydrophilic polymeric substance, the core being coated with the porous film. Disclosed is also a method for producing the same. The controlled release pharmaceutical preparation of this invention posseses a desired dissolution rate by controlling the porosity of the porous film.
    Type: Grant
    Filed: July 12, 1991
    Date of Patent: October 19, 1993
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Kazuo Noda, Yoshiyuki Hirakawa, Hiroyuki Yoshino
  • Process for micronizing slightly-soluble drug
    Patent number: 5202129
    Abstract: A process for micronizing a slightly-soluble drug characterized by subjecting a mixture of said drug and a sugar or sugar alcohol to high-speed stirring comminution or impact comminution in order to produce a micronized drug having an average diameter of less than about 2-3 mm. Also provided is a pharmaceutical formulation which comprises the micronized drug.
    Type: Grant
    Filed: August 3, 1990
    Date of Patent: April 13, 1993
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Kazuo Noda, Masao Kobayashi, Takashi Osawa
  • Controlled release pharmaceutical preparation and method for producing the same
    Patent number: 5068112
    Abstract: Disclosed is a controlled release pharmaceutical preparation, comprising a core containing a pharmaceutically active ingredient, and a porous film of a hydrophobic polymeric substance or a hydrophobic polymeric substance and a hydrophilic polymeric substance, the core being coated with the porous film. Disclosed is also a method for producing the same. The controlled release pharmaceutical preparation of this invention posseses a desired dissolution rate by controlling the porosity of the porous film.
    Type: Grant
    Filed: March 24, 1989
    Date of Patent: November 26, 1991
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Kazuo Noda, Yoshiyuki Hirakawa, Hiroyuki Yoshino
  • Controlled release dosage form
    Patent number: 4963365
    Abstract: A controlled release dosage form which consists essentially of a core containing a medicament; an inner coating layer composed of ethylcellulose and a hydrophobic substance; and an outer coating layer containing a medicament are disclosed. Said dosage form shows rapid increase in blood concentration of the medicament and at the same time maintains the high level of the blood concentration over a prolonged period time.
    Type: Grant
    Filed: November 4, 1988
    Date of Patent: October 16, 1990
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Kazuo Noda, Masao Kobayashi, Shigeyuki Ishikawa
  • Parenteral alimentation solution
    Patent number: 4670261
    Abstract: A parenteral alimentation solution having excellent nutritional properties with preventing problems such as browning which comprises three components of a reducing sugar, amino acids and electrolytes in a specific composition and a specific amount.
    Type: Grant
    Filed: September 24, 1985
    Date of Patent: June 2, 1987
    Assignees: Tanabe Seiyaku Co., Ltd., Terumo Kabushiki Kaisha
    Inventors: Masayoshi Samejima, Saburo Matsuda, Toshio Wakabayashi, Naoki Hayakawa
  • Process for preparing free-flowing ethylcellulose microcapsules
    Patent number: 4542042
    Abstract: A process for preparing free-flowing microcapsules by taking advantage of the phase-separation of ethylcellulose in cyclohexane is disclosed. In this process, a hydrocarbon compound which is soluble in cyclohexane and have a molecular weight of 150 to 3,000 and a solubility parameter (.delta., at 25.degree. C.) of 7 to 10 (cal/cm.sup.3).sup.1/2 is used as the phase-separation-inducing agent.
    Type: Grant
    Filed: July 1, 1983
    Date of Patent: September 17, 1985
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Goichi Hirata, Takashi Ishibashi
  • Process for preparing ethylcellulose microcapsules
    Patent number: 4486471
    Abstract: Pharmaceutically active compound-containing microcapsules the coating walls of which consist essentially of ethylcellulose and a water-insoluble, acid-soluble polymer material are disclosed. A method of preparing said microcapsules is also disclosed.
    Type: Grant
    Filed: May 5, 1982
    Date of Patent: December 4, 1984
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Goichi Hirata, Yoshiyuki Koida, Akira Kida
  • Microcapsules and method of preparing same
    Patent number: 4462982
    Abstract: Ethylcellulose microcapsules, wherein a polymer material which shows at least 1.2 times increase in weight by immersing it in water at 37.degree. C. is incorporated into the ethylcellulose coating walls and/or the core material thereof, are disclosed. Said ethylcellulose microcapsules show rapid release of the core material in digestive organs such as stomach.
    Type: Grant
    Filed: September 17, 1982
    Date of Patent: July 31, 1984
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Goichi Hirata, Yoshiyuki Koida, Yoshinori Kobayashi, Akira Kida
  • Method of preparing microcapsules
    Patent number: 4443497
    Abstract: Microcapsules are prepared by conducting the phase-separation of a coating polymer material in the presence of ethylcellulose. Ethylcellulose present in the phase separation system minimizes the coagulation of the coating polymer material.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: April 17, 1984
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Goichi Hirata
  • Process for preparing ethylcellulose microcapsules
    Patent number: 4411933
    Abstract: A process for preparing ethylcellulose microcapsules by flocculation of the ethylcellulose is disclosed. In this process, the flocculation of the ethylcellulose is carried out in the presence of an organosilicon polymer or in the presence of said organosilicon polymer and a surfactant.
    Type: Grant
    Filed: April 9, 1981
    Date of Patent: October 25, 1983
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Goichi Hirata
  • Process for preparing pharmaceutically active compound-containing microcapsules
    Patent number: 4389331
    Abstract: A process for preparing ethylcellulose microcapsules of a pharmaceutically active compound by phase separation-coacervation of the ethylcellulose is disclosed. In this process, phospholipids are used as a phase-separation-inducing agent.
    Type: Grant
    Filed: October 7, 1980
    Date of Patent: June 21, 1983
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Goichi Hirata, Yoshiyuki Koida
  • Process for the preparation of pharmaceutical substance-containing microcapsules
    Patent number: 4218333
    Abstract: A process for the preparation of pharmaceutical substance-containing microcapsules by liquid-liquid phase separation is disclosed. In this process, ethyl cellulose having an ethoxy content of about 48 to about 49.5% by weight is used as a wall-forming agent and polyisobutylene is used as a phase separation inducing agent, and both or either one of the ethyl cellulose and polyisobutylene are used in the form of a mixture of two kinds differing in the average molecular weight.
    Type: Grant
    Filed: July 31, 1978
    Date of Patent: August 19, 1980
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Masayoshi Samejima, Goichi Hirata