Abstract: A washing apparatus includes a stage, a suction nozzle, and a control unit. On the stage, an analytical unit is mounted. In the analytical unit, a well having a hole shape including a bottom surface and an inner peripheral surface is formed. The suction nozzle sucks a solution in the well. The control unit, after controlling the suction nozzle to sucks the solution in the well, controls the stage to rotate the stage on which the analytical unit is mounted at a predetermined speed of rotation, and controls the suction nozzle to suck a residue of the solution existing in the well.

Abstract: In a method for manufacturing a nitride semiconductor light-emitting element by splitting a semiconductor layer stacked substrate including a semiconductor layer stacked body with a plurality of waveguides extending along the Y-axis to fabricate a bar-shaped substrate, and splitting the bar-shaped substrate along a lengthwise split line to fabricate an individual element, the waveguide in the individual element has different widths at one end portion and the other end portion and the center line of the waveguide is located off the center of the individual element along the X-axis, and in the semiconductor layer stacked substrate including a first element forming region and a second element forming region which are adjacent to each other along the X-axis, two lengthwise split lines sandwiching the first element forming region and two lengthwise split lines sandwiching the second element forming region are misaligned along the X-axis.

Abstract: An analysis device includes a turntable holding a substrate, an optical pickup driven in a direction perpendicular to a rotation axis of the turntable and configured to emit laser light to reaction regions and to receive reflected light from the respective reaction regions, an optical pickup drive circuit, and a controller. The reaction regions are formed at positions different from the center of the substrate. The center of the substrate is located on the rotation axis of the turntable. The optical pickup detects a reception level of the reflected light to generate a light reception level signal. The controller controls a turntable drive circuit to rotate the substrate, controls the optical pickup drive circuit to drive the optical pickup, and specifies the respective reaction regions in accordance with a positional information signal and the light reception level signal.

Abstract: A pancreatic cancer detection method is provided, including: (a) bringing extracellular vesicles, which are in a body fluid sample derived from a subject into contact with one or more kinds of lectins; (b) measuring an amount of the extracellular vesicles bound to the one or more kinds of lectins after (a); and (c) evaluating the presence of pancreatic cancer in the subject based on the amount of the extracellular vesicles measured in (b). In addition, a pancreatic cancer detection kit is provided, including: a solid-phase carrier on which one or more kinds of lectins are immobilized; and an antibody specifically binding to a pan-extracellular vesicle membrane protein or an antigen-binding fragment thereof.

Abstract: A method of fabricating a substrate for analysis fixes antibodies that specifically react with specific antigens included in detection target substances to the substrate for analysis. The method subjects the substrate for analysis to immersion treatment with a predetermined treatment solution so as to form antibody aggregations in which the antibodies are aggregated at boundary regions between recesses and convex portions on the substrate for analysis. The method causes the antigens and the antibodies to react with each other so as to capture the detection target substances on the substrate for analysis by the antibody aggregations.

Abstract: A semiconductor laser apparatus includes: a semiconductor laser device for junction down mounting that includes a first light-emitting device region and a second light-emitting device region formed separately on a substrate. The first light-emitting device region and the second light-emitting device region in the semiconductor laser device each have a stack structure in which an n-type semiconductor layer, an active layer, and a p-type semiconductor layer are stacked in stated order. The first light-emitting device region includes a first electrode film located on the n-type semiconductor layer. The second light-emitting device region includes a second electrode film located on the p-type semiconductor layer. The first electrode film and the second electrode film are electrically connected to each other.

Abstract: An analysis device includes a controller configured to count a pulse derived from a particles as a plural particles when a light reception level signal includes the pulse having a first extreme value point, a second extreme value point, and a third extreme value point, and the pulse fulfils a condition in which the third extreme value point is present between the first extreme value point and the second extreme value point in a pulse width direction of the pulse, the third extreme value point is present between the first extreme value point and a threshold in a pulse amplitude direction, the first extreme value point and the second extreme value point are each an extreme value point of a waveform projecting in a common direction, and the third extreme value point is an extreme value point of a waveform in a direction opposite to the common direction.

Abstract: A first sample solution including exosomes including first to third detection target substances is mixed with a first buffer solution including first nanoparticles including first binding substances which bind to the first detection target substances. The first detection target substances and the first binding substances are bound together, so as to form first complexes of the exosomes and the first nanoparticles. The first complexes are isolated from a mixed solution of the first sample solution and the first buffer solution. The second detection target substances and the second binding substances are bound together, so as to capture the first complexes on a substrate. The second binding substances are fixed onto the substrate. A second buffer solution including second nanoparticles including third binding substances which bind to the third detection target substances is reacted with the first complexes.

Abstract: An analysis threshold generation device includes a threshold calculation unit for generating a pair of thresholds for a pulse width of a pulse included in a light reception level signal or a pair of thresholds for a pulse amplitude of the pulse. The analysis threshold generation device includes a threshold correction unit for generating a pair of thresholds used for analysis in accordance with the pair of thresholds generated by the threshold calculation unit and a count value output from a pulse count unit. The threshold calculation unit repeatedly generates a new pair of thresholds in which at least one of the pair of thresholds is changed every time the pulse count unit counts the pulse until reaching a predetermined value.

Abstract: A device includes a first port in which a first address as a monitoring point is set and which is connected to one communication line belonging to a link aggregation group to which another communication line for another device also belongs, and a processor configured to transmit and receive a monitoring frame based on the first address through the first port, switch an operating state of the first port to an active state or a standby state, and restrict the transmission and the reception of the monitoring frame through the first port when the operating state of the first port is switched to the standby state, wherein the first address is identical to a second address which is set as a monitoring point in a second port of the other device connected to the other communication line belonging to the link aggregation group to which the one communication line belongs.

Abstract: A puncture forming method is a method of forming punctures in a sample by irradiating a surface of the sample with a light beam. The puncture forming method includes: forming a first puncture by irradiating a first position on the surface of the sample with a first pulse of the light beam; and after the forming of the first puncture, forming a second puncture which at least partially overlaps the first puncture by irradiating, with a second pulse of the light beam, a second position on the surface of the sample positioned away from the first position in a first direction. The second puncture has a tip which is positioned inside the sample and which is bent in a direction opposite to the first direction.

Abstract: An analysis device includes a turntable, an optical pickup, and a controller. The turntable holds a specimen analysis disc having reaction regions on which nanoparticles binding to substances to be detected are captured. The optical pickup emits laser light to each reaction region, receives a reflected light from each reaction region, and generates a light reception level signal. The controller sequentially generates a plurality of measurement gate signals for counting the number of the nanoparticles captured on each reaction region, counts the number of the nanoparticles of each of the measurement gate signals based on the light reception level signal, specifies a measurement gate section in each reaction region according to a measurement result per measurement gate signal, and adds up the number of the nanoparticles of the respective measurement gate signals in the measurement gate section.

Abstract: A vehicle lamp is a vehicle lamp having a light source unit configured to radiate light forward and disposed inside of a lighting body constituted by a housing having an opened front surface and a lens cover that covers the opening of the housing, the light source unit includes a circuit board to which a female connector is attached, and a wiring cord to which a male connector is attached, and the housing includes a restricting section that serves as a stopper of the male connector at a position facing an end portion of the male connector on a side opposite to the male connector in an insertion direction of the male connector in a state in which the male connector is inserted into the female connector.

Abstract: An analysis unit for quantitating detection target substances bound to antibodies includes wells and inclination parts. The wells each have a hole-like shape defined by an opening, an inner circumferential surface, and a bottom. The inclination parts each have an inclined surface connected to the inner circumferential surface and inclined downward such that whose height with respect to the bottom decreases as a distance from an outer circumferential side of the well increases.

Abstract: A washing apparatus includes a stage, a suction nozzle, and a control unit. On the stage, an analytical unit is mounted. In the analytical unit, a well having a hole shape including a bottom surface and an inner peripheral surface is formed. The suction nozzle sucks a solution in the well. The control unit, after controlling the suction nozzle to sucks the solution in the well, controls the stage to rotate the stage on which the analytical unit is mounted at a predetermined speed of rotation, and controls the suction nozzle to suck a residue of the solution existing in the well.

Abstract: A vehicle lamp is a vehicle lamp having a light source unit configured to radiate light forward and disposed inside of a lighting body constituted by a housing having an opened front surface and a lens cover that covers the opening of the housing, the light source unit includes a circuit board to which a female connector is attached, and a wiring cord to which a male connector is attached, and the housing includes a restricting section that serves as a stopper of the male connector at a position facing an end portion of the male connector on a side opposite to the male connector in an insertion direction of the male connector in a state in which the male connector is inserted into the female connector.

Abstract: The dispensing unit includes a disc, a cartridge, and a dispensing holder. The disc has a disc shape and includes a track region provided with recesses and projections alternately arranged in a radial direction. The cartridge includes a penetration hole, and a well is formed by the penetration hole and the track region in a state in which the cartridge is attached to the disc. The dispensing holder includes a holding part to be inserted into the penetration hole, and a guide hole penetrating the holding part. The guide hole has a truncated cone shape in which a first opening diameter on the holding part side is smaller than a second opening diameter on a side opposite to the holding part, and a center line of the guide hole is located on a line passing through the center of the disc and the center of the well.

Abstract: An apparatus includes a first port coupled to a first apparatus through a ring line, a second port coupled to a second apparatus through a second line, the second apparatus disposed external to the ring line, the second line configured redundantly with a first line between the first apparatus and the second apparatus, a third port coupled to the first apparatus through a control line for a control signal concerning the first line, and circuitry that detects a fault in the control line, wherein the circuitry detects a fault in the second line, switches the second line from an active line to a standby line in accordance with the detection of the fault in the second line, and while the fault in the control line is detected, shuts down the first port in accordance with the detection of the fault in the second line.

Abstract: An analysis substrate is irradiated with laser light, and reflected light from reaction region is received to generate a light reception level signal. Particle detection signal having a signal level higher than a predetermined signal level is extracted from the light reception level signal in the reaction region, so as to detect detection target substance in accordance with the extracted particle detection signal. The analysis substrate has the reaction region on which the detection target substance, primary particle provided with antibody for labeling the detection target substance, and secondary particle formed of metal and provided with antigen to be bound to the antibody are captured.

Abstract: A magnet structure includes first and second magnet units. The first magnet unit is provided with a first magnet fixing section that includes a first surface and a first magnet having a first polarity on the first surface's side. The second magnet unit is provided with a second magnet fixing section that includes a second surface and a second magnet having a second polarity on the second surface's side, the second polarity being an opposite polarity to the first polarity. The first and second surfaces are located next to one another on the same plane to form a magnetic attachment surface which is magnetically attached to a magnetically-attached object. The second magnet unit is supported by the first magnet unit so as to move in a predetermined range.