Abstract: An antibody-drug conjugate represented by formula (I): (where Ab is an antibody, X is a group represented by formula (X-1), formula (X-2) or formula (X-3): (where at the left represents the binding site with NH and at the right represents the binding side with D), D is a group represented by formula (D-1) or formula (D-2): (where represents the binding site with X), and n is in the range of about 1 to about 8).

Abstract: The disclosure provides a vehicle body rear structure, which can reduce damage to the vehicle during a collision from the rear. The vehicle body rear structure includes a chassis rear, a hook reinforcement part fixed to a lower surface of the chassis rear; and a hook fixed on a back side of the chassis rear through the hook reinforcement part, in which the hook reinforcement part includes a plurality of part members independent from each other, the plurality of part members are connected in series and joined in a front-back direction of the vehicle to form a joint boundary part, and the joint boundary part is disposed with a weakened part on a side close to the chassis rear.

Abstract: The present disclosure provides a method of treating or preventing a disease or condition associated with fibrosis and/or diabetes in a subject in need thereof comprising subcutaneously administering to the subject one or more effective doses of a fibroblast growth factor 21 (FGF-21) polypeptide, e.g., FGF-21 conjugate, e.g., PEG-FGF-21.

Abstract: This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.

Abstract: An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

Abstract: A material discharge device includes: a drive motor; a screw having a groove formation surface and configured to rotate; a barrel having a facing surface and formed with a communication hole through which a plasticized material flows; a heating unit configured to heat the material; a nozzle from which the material is injected to an outside; and a plurality of measurement units configured to measure a pressure or a temperature of the material. The measurement units are disposed at an outer periphery of a nozzle channel wall, and a thickness of the nozzle channel wall satisfies the following (1) or (2): (1) when the nozzle channel wall is made of a material containing iron as a main component, the thickness of the nozzle channel wall is 0.2 mm or more and 2.5 mm or less; and (2) when the nozzle channel wall is made of a material containing aluminum as a main component, the thickness of the nozzle channel wall is 0.2 mm or more and 4 mm or less.

Abstract: A seat back pad 70 has a groove 73 for tucking a skin material therein, formed at borders between a central portion 71 and side portions 72. A hole (slot hole 74) is formed in a bottom of the groove 73 along the groove 73. A tuck-in wire 76 for tucking the skin material in includes a plurality of tuck-in portions 76A provided along the groove 73, and a connecting portion (detour portion 76B) detouring around the hole and connecting the tuck-in portions 76A. With this configuration, when an upper body of an occupant P subsides into a seat back S2 in a rear-end collision of a vehicle, the central portion 71, defined by the groove 73 as a border, is easily and sufficiently moved rearward relative to the left and right side portions 72. Furthermore, the tuck-in wire 76 is not exposed through the hole, and thus adhesion between the seat back pad 70 and the tuck-in wire 76 can be improved.

Abstract: A virtual image display device includes: a switching mechanism for switching a position of a view angle including a first position and a second position; and a display control unit for displaying the virtual image in response to a switching of the position of the view angle by the switching mechanism. When the display control unit displays a specific content within the view angle at the second position after the switching mechanism switches the view angle from the first position to the second position, the display control unit starts displaying a related content preliminarily associated with the specific content before the switching of the view angle to the second position is completed.

Abstract: A seat back pad 70 has a groove 73 for tucking a skin material therein, formed at borders between a central portion 71 and side portions 72. A hole (slot hole 74) is formed in a bottom of the groove 73 along the groove 73. A tuck-in wire 76 for tucking the skin material in includes a plurality of tuck-in portions 76A provided along the groove 73, and a connecting portion (detour portion 76B) detouring around the hole and connecting the tuck-in portions 76A. With this configuration, when an upper body of an occupant P subsides into a seat back S2 in a rear-end collision of a vehicle, the central portion 71, defined by the groove 73 as a border, is easily and sufficiently moved rearward relative to the left and right side portions 72. Furthermore, the tuck-in wire 76 is not exposed through the hole, and thus adhesion between the seat back pad 70 and the tuck-in wire 76 can be improved.

Abstract: A seat back pad 70 has a groove 73 for tucking a skin material therein, formed at borders between a central portion 71 and side portions 72. A hole (slot hole 74) is formed in a bottom of the groove 73 along the groove 73. A tuck-in wire 76 for tucking the skin material in includes a plurality of tuck-in portions 76A provided along the groove 73, and a connecting portion (detour portion 76B) detouring around the hole and connecting the tuck-in portions 76A. With this configuration, when an upper body of an occupant P subsides into a seat back S2 in a rear-end collision of a vehicle, the central portion 71, defined by the groove 73 as a border, is easily and sufficiently moved rearward relative to the left and right side portions 72. Furthermore, the tuck-in wire 76 is not exposed through the hole, and thus adhesion between the seat back pad 70 and the tuck-in wire 76 can be improved.

Abstract: An information processing apparatus includes a processor configured to acquire a text recognition result including a text string included in an image and position information of the text string in the image, display the text string included in the text recognition result, and specify, in a case where the displayed text string is corrected, position information corresponding to the corrected text string, among pieces of the position information associated with each text string included in the text recognition result.

Abstract: A liquid-mixing apparatus used in a liquid-mixing method comprises a plurality of supply valves provided to a cylinder. The supply valves make it possible to individually supply a plurality of types of liquids into a retention chamber. Each of the supply valves is configured so as to be switchable between an open state, in which the interior of a supply channel via which a liquid is supplied and the interior of the retention chamber intercommunicate, and a closed state, in which communication between the supply channel and the retention chamber is blocked. A piston moves in the direction in which the volume of the retention chamber increases while at least one of the supply valves is in the open state, whereby a liquid is drawn into the storage chamber.

Abstract: An information processing apparatus includes a processor configured to acquire a form image that is obtained from reading of a form in which form information including at least one of a predetermined item or an item value is written, extract the form information from the acquired form image, identify a reference form corresponding to the form image from the extracted form information, correct a revised position using a difference between a position of form information, of which a corresponding reference position is not revised, of the extracted form information and a reference position corresponding to the position, in a case where the reference position of form information of the reference form is revised to the revised position by user's designation, and extract the form information at the corrected revised position.

Abstract: A coating method comprises a workpiece acquiring step of acquiring a workpiece in which a metal member and a resin member the surface of which is activated by electron beam irradiation are connected to each other, and a coating step of applying a coating material to the metal member and the resin member of the workpiece.

Abstract: An information processing apparatus includes a processor configured to acquire text string information corresponding to a predetermined item in a digitized form and position information of the text string information, put the acquired text string information into an unrecognizable state in a display of the form by using the acquired position information for the item, and change the unrecognizable state to a recognizable state by performing a predetermined operation on the item.

Abstract: An information processing apparatus includes a processor configured to acquire specific document data, and in a case where the specific document data includes a text code string, output the text code string included in the specific document data as input data for processing executed by outputting a text code string obtained by text recognition of document data in a predetermined format, in the predetermined format.

Abstract: An information processing apparatus includes a processor configured to acquire plural scanned images obtained by scanning a bundle of paper media including a plural standard document bundles each of which is a set of a standard document and a related document related to the standard document, extract a title from the plural scanned images, extract, from the plural scanned images, an identifier that is assigned to be common within one standard document bundle and to be different between different standard document bundles, and divide the plural scanned images into bundles such that a scanned image from which the title is extracted is set as a bundle head, scanned images having the same identifier are included in the same bundle, and scanned images having different identifiers are included in different bundles.

Abstract: A coating method includes a coating step of applying coating material to a workpiece, and a curing step of curing the coating material by irradiating the applied coating material with an electron beam emitted from an electron beam irradiation unit, wherein in the curing step, a potential of the workpiece is higher than a potential of the electron beam irradiation unit.

Abstract: An information processing device includes: a processor configured to: execute, as preprocessing prior to character recognition, image conversion processing for a document that is a target of the character recognition, the image conversion processing having been determined in advance for each of attributes in the document or for each of regions in the document, the regions having been determined in advance according to a document type; and execute processing of executing the character recognition for the document that has been subjected to the image conversion processing to output a result of the character recognition.

Abstract: A virtual image display device includes a polarization adjustment member that includes a polarizing plate and a support plate. The polarizing plate has a property of blocking a light which is oscillated in an axial direction of a block axis while the polarizing plate is in a state where a residual stress, a degree of which is maximized in a first residual stress direction along a plane of the polarizing plate, is left in the polarizing plate. The support plate supports the polarizing plate while the support plate is in a state where a residual stress, a degree of which is maximized in a second residual stress direction along a plane of the support plate, is left in the support plate. The polarizing plate and the support plate are bonded together such that the first residual stress direction is along the second residual stress direction.