Patents by Inventor Massimiliano Forcato

Massimiliano Forcato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARING SPHERICAL AGGLOMERATES OF TIMAPIPRANT
    Publication number: 20220184059
    Abstract: The present invention relates to a process for the preparation of spherical agglomerates of timapiprant; the invention also relates to spherical agglomerates of timapiprant obtained by the above process.
    Type: Application
    Filed: December 19, 2019
    Publication date: June 16, 2022
    Inventors: Eric MERIFIELD, Massimiliano FORCATO, Alain BURGOS
  • Process for producing a solid form of abiraterone acetate
    Patent number: 9920089
    Abstract: The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of preparing micro size abiraterone or derivatives thereof in high yield and purity by means of a spherical agglomeration process.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: March 20, 2018
    Assignee: ZACH SYSTEM
    Inventors: Patricia Poirier, Yvon Derrien, Massimiliano Forcato, Livius Cotarca, Pierrick Morice
  • Process for preparing Cinacalcet hydrochloride
    Patent number: 9522869
    Abstract: A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine hydrochloride salt of formula (I) i.e. Cinacalcet hydrochloride and its intermediates of formulae (VII) and (VIII) wherein Z is chloride or another pharmaceutically acceptable anionic counterion.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: December 20, 2016
    Assignee: ZACH SYSTEM S.P.A.
    Inventors: Nicola Catozzi, Livius Cotarca, Johnny Foletto, Massimiliano Forcato, Roberto Giovanetti, Giorgio Soriato, Massimo Verzini
  • Process for preparing 17-substituted steroids
    Patent number: 9353145
    Abstract: The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of synthesizing abiraterone or derivatives thereof in high yield and purity by means of a key 3-formate intermediate.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: May 31, 2016
    Assignee: ZACH SYSTEM
    Inventors: Yvon Derrien, Patricia Poirier, Massimiliano Forcato, Tony Pintus, Livius Cotarca, Sebastien Meunier, Laurence Graindorge
  • PROCESS FOR PRODUCING A SOLID FORM OF ABIRATERONE ACETATE
    Publication number: 20160083416
    Abstract: The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of preparing micro size abiraterone or derivatives thereof in high yield and purity by means of a spherical agglomeration process.
    Type: Application
    Filed: April 11, 2014
    Publication date: March 24, 2016
    Applicant: ZACH SYSTEM
    Inventors: Patricia POIRIER, Yvon DERRIEN, Massimiliano FORCATO, Livius COTARCA, Pierrick MORICE
  • PROCESS FOR PREPARING CINACALCET HYDROCHLORIDE
    Publication number: 20140296574
    Abstract: A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine hydrochloride salt of formula (I) i.e. Cinacalcet hydrochloride and its intermediates of formulae (VII) and (VIII) wherein Z is chloride or another pharmaceutically acceptable anionic counterion.
    Type: Application
    Filed: June 13, 2014
    Publication date: October 2, 2014
    Inventors: Nicola Catozzi, Livius Cotarca, Johnny Foletto, Massimiliano Forcato, Roberto Giovanetti, Giorgio Soriato, Massimo Verzini
  • PROCESS FOR PREPARING 17-SUBSTITUTED STEROIDS
    Publication number: 20140256932
    Abstract: The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of synthesizing abiraterone or derivatives thereof in high yield and purity by means of a key 3-formate intermediate.
    Type: Application
    Filed: October 9, 2012
    Publication date: September 11, 2014
    Applicant: ZACH SYSTEM
    Inventors: Yvon Derrien, Patricia Poirier, Massimiliano Forcato, Tony Pintus, Livius Cotarca, Sebastien Meunier, Laurence Graindorge
  • Process for preparing cinacalcet
    Patent number: 8637708
    Abstract: A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine of formula hydrochloride salt of formula (I) i.e. Cinacalcet.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: January 28, 2014
    Assignee: Zach System S.p.A.
    Inventors: Nicola Catozzi, Livius Cotarca, Johnny Foletto, Massimiliano Forcato, Roberto Giovanetti, Giorgio Soriato, Massimo Verzini
  • Process for preparing Cinacalcet
    Patent number: 8614353
    Abstract: A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine of formula (I) i.e. Cinacalcet and its intermediates of formulae (V), (Va) and (Vb).
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: December 24, 2013
    Assignee: Zach System S.p.A.
    Inventors: Nicola Catozzi, Johnny Foletto, Massimiliano Forcato, Roberto Giovanetti, Giorgio Soriato, Massimo Verzini
  • PROCESS FOR PREPARING CINACALCET
    Publication number: 20120238778
    Abstract: A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine of formula hydrochloride salt of formula (I) i.e. Cinacalcet.
    Type: Application
    Filed: September 8, 2010
    Publication date: September 20, 2012
    Applicant: ZACH SYSTEM S.P.A.
    Inventors: Nicola Catozzi, Livius Cotarca, Johnny Foletto, Massimiliano Forcato, Roberto Giovanetti, Giorgio Soriato, Massimo Verzini
  • PROCESS FOR PREPARING CINACALCET HYDROCHLORIDE
    Publication number: 20110306794
    Abstract: A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine hydrochloride salt of formula (I) i.e. Cinacalcet hydrochloride and its intermediates of formulae (VII) and (VIII) wherein Z is chloride or another pharmaceutically acceptable anionic counterion.
    Type: Application
    Filed: February 16, 2010
    Publication date: December 15, 2011
    Applicant: ZACH SYSTEM S.P.A.
    Inventors: Nicola Catozzi, Livius Cotarca, Johnny Foletto, Massimiliano Forcato, Roberto Giovanetti, Giorgio Soriato, Massimo Verzini
  • PROCESS FOR PREPARING CINACALCET
    Publication number: 20110207965
    Abstract: A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine of formula (I) i.e. Cinacalcet and its intermediates of formulae (V), (Va) and (Vb).
    Type: Application
    Filed: October 16, 2009
    Publication date: August 25, 2011
    Applicant: ZACH SYSTEM S.P.A.
    Inventors: Nicola Catozzi, Johnny Foletto, Massimiliano Forcato, Roberto Giovanetti, Giorgio Soriato, Massimo Verzini
  • Process for the preparation of levetiracetam
    Patent number: 7939676
    Abstract: A process for the manufacturing of levetiracetam, wherein said process comprises the steps of: (1) reacting the (?)-(S)-alpha-ethyl-2-oxo-1-pyrrolidine acetic acid with a substoichiometric amount of an activating agent in an alcoholic solvent, and (2) subjecting the resulting reaction solution of step (1) to an ammonolysis process with gaseous ammonia.
    Type: Grant
    Filed: September 17, 2009
    Date of Patent: May 10, 2011
    Assignee: Zach System S.p.A.
    Inventors: Corrado Colli, Massimiliano Forcato, Livius Cotarca
  • Process for the preparation of Levetiracetam
    Publication number: 20110065932
    Abstract: A process for the manufacturing of levetiracetam, wherein said process comprises the steps of: (1) reacting the (?)-(S)-alpha-ethyl-2-oxo-1-pyrrolidine acetic acid with a substoichiometric amount of an activating agent in an alcoholic solvent, and (2) subjecting the resulting reaction solution of step (1) to an ammonolysis process with gaseous ammonia.
    Type: Application
    Filed: September 17, 2009
    Publication date: March 17, 2011
    Applicant: ZACH SYSTEM S.P.A.
    Inventors: Corrado Colli, Massimiliano Forcato, Livius Cotarca
  • PROCESS FOR THE PREPARATION OF LEVETIRACETAM
    Publication number: 20100076204
    Abstract: The present invention relates to a process for the preparation of levetiracetam and, more particularly, to an improved process for the preparation of levetiracetam characterized by a crystallization-induced dynamic resolution of a diastereoisomeric mixture of an (±)-alpha-ethyl-2-oxo-1-pyrrolidine acetamide derivative.
    Type: Application
    Filed: July 20, 2007
    Publication date: March 25, 2010
    Applicant: ZACH SYSTEM S.P.A.
    Inventors: Massimiliano FORCATO, Ivan MICHIELETTO, Paolo MARAGNI, Franco MASSACCESI, Livius COTARCA