Patents by Inventor Mathias K. Herrlein

Mathias K. Herrlein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Covalent lock for self-assembled oligonucleotide constructs
    Patent number: 5780613
    Abstract: A method of autoligating self-assembled oligonucleotide blocks is disclosed. The method includes the step of displacing a 5' displaceable group by a 3' thiophosphoryl group to form an --OP(O)(O.sup.-)S-- internucleoside linkage.
    Type: Grant
    Filed: August 1, 1995
    Date of Patent: July 14, 1998
    Assignee: Northwestern University
    Inventors: Robert L. Letsinger, Mathias K. Herrlein