Abstract: The invention relates to the field of apoptosis. The invention provides novel therapeutic substances, for example, novel therapeutic proteinaceous compounds that can contain apoptin alone or jointly with other proteinaceous protein or protein fragments, especially in those cases when cells are derailed such as cancer-, autoimmune-derived cells.

Abstract: The invention related to activation of apoptin-induced apoptosis by different cell-transforming agents in normal and or cancer-prone cells. Apoptin, also called VP3, is a viral protein derived from the Chicken anemia virus. Also the invention related to preventive anti-tumor therapies of normal and/or cancer-prone cells. Treatment of normal and/or cancer prone cells with tumor-inducing agents will activate apoptin-induced apoptosis, resulting in the elimination of potential tumor cells. Also the invention relates to diagnosis of cancer agents. Agents with tumor activity can be examined by expressing them in normal cells and analyzing their capability of enabling apoptin-induced apoptosis.

Abstract: Recombinant genetic information (DNA or RNA), comprising a Chicken Anemia Virus (CAV)-specific nucleotide sequence and the use thereof for diagnostics, vaccination or protein production. Recombinant CAV protein and the use thereof for diagnostics, vaccination or production of CAV-specific antibodies. The use of CAV-specific antibodies thus obtained.

Abstract: The invention relates to the field of apoptosis. The invention provides novel therapeutic substances, for example novel therapeutic proteinaceous compounds that can contain apoptin alone or jointly with other proteinaceous protein or protein fragments, especially in those cases when cells are derailed such as cancer-, auto-immune-derived cells.