Patents by Inventor Matthew Abelman

Matthew Abelman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUINAZOLINONE DERIVATIVES AS ALDH-2 INHIBITORS
    Publication number: 20080249116
    Abstract: Disclosed are novel quinazolinone derivatives, useful as ALDH-2 inhibitors for treating mammals for various disease states, such as treatment for cocaine dependency or alcohol dependency.
    Type: Application
    Filed: April 3, 2008
    Publication date: October 9, 2008
    Inventors: Jeff Zablocki, Matthew Abelman, Michael Organ
  • ABCA1 elevating compounds
    Patent number: 7432276
    Abstract: The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.
    Type: Grant
    Filed: December 27, 2006
    Date of Patent: October 7, 2008
    Assignee: CV Therapeutics, Inc.
    Inventors: Matthew Abelman, Robert Jiang, Jeff Zablocki, Dmitry Koltun, Melanie Boze
  • ABCA1 elevating compounds
    Patent number: 7423045
    Abstract: The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: September 9, 2008
    Assignee: CV Therapeutics, Inc.
    Inventors: Matthew Abelman, Robert Jiang, Jeff Zablocki, Dmitry Koltun
  • ALDH-2 INHIBITORS IN THE TREATMENT OF ADDICTION
    Publication number: 20080207610
    Abstract: Disclosed are novel isoflavone derivatives having the structure of Formula I which are useful as ALDH-2 inhibitors for treating mammals for dependence upon drugs of addiction, for example addiction to dopamine-producing agent such as cocaine, morphine, amphetamines, nicotine, and alcohol.
    Type: Application
    Filed: January 24, 2008
    Publication date: August 28, 2008
    Inventors: Jeff Zablocki, Matthew Abelman, Michael Organ, Yaroslav Bilokin, Robert Jiang, Elfatih Elzein, Tetsuya Kobayashi, Rao Kalla, Thao Perry, Xiaofen Li, Ivan Diamond, Lina Yao, Peidong Fan, Maria Pia Arolfo, Zhan Jiang
  • ALDH-2 INHIBITORS IN THE TREATMENT OF DRUG ADDICTION
    Publication number: 20080032995
    Abstract: Disclosed are novel isoflavone derivatives having the structure of Formula I which are useful as ALDH-2 inhibitors for treating mammals for dependence upon drugs of addiction, for example addiction to dopamine-producing agent such as cocaine, morphine, amphetamines, nicotine, and alcohol.
    Type: Application
    Filed: July 27, 2007
    Publication date: February 7, 2008
    Inventors: Jeff Zablocki, Matthew Abelman, Michael Organ, Yaroslav Bilokin, Ivan Diamond, Maria Arolfo, Lina Yao, Peidong Fan, Elfatih Elzein, Rao Kalla, Thao Perry, Tetsuya Kobayshi, Xiaofen Lee, Robert Jiang
  • ABCA1 elevating compounds
    Publication number: 20070191379
    Abstract: The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.
    Type: Application
    Filed: December 27, 2006
    Publication date: August 16, 2007
    Inventors: Matthew Abelman, Robert Jiang, Jeff Zablocki, Dmitry Koltun, Melanie Boze
  • ABCA1 elevating compounds
    Publication number: 20070010544
    Abstract: The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.
    Type: Application
    Filed: June 28, 2006
    Publication date: January 11, 2007
    Inventors: Matthew Abelman, Robert Jiang, Jeff Zablocki, Dmitry Koltun