Patents by Inventor Matthew D. Landrigan
Matthew D. Landrigan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11759795Abstract: A blood washing system (20) having a rotor (22) defining an internal chamber for receiving a multi-component fluid and a skimmer assembly (24) including a moveable buoy (28) having an orifice (32) fluidly connected to an access port for the rotor for selectively withdrawing separated fractions of the multi-component fluid. The multi-component fluid can be fed into the internal chamber before the rotor (22) can be rotated at a first speed to fractionate the multi-component fluid. A brake can be applied to the rotor to slow rotation of the rotor to a slower second speed or stop rotation of the rotor causing the solid and denser fluid fractions to settle on the bottom wall (44) of the rotor (22). The buoy (28) can have a specific gravity corresponding to a selected fraction such that the buoy floats on a surface of the selected fraction, wherein the fractions floating on the selected fraction can be withdrawn through the orifice (32).Type: GrantFiled: May 18, 2018Date of Patent: September 19, 2023Assignee: Zimmer, Inc.Inventors: Randel E. Dorian, Matthew D. Landrigan, Kyle Kausch
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Publication number: 20200197956Abstract: A blood washing system (20) having a rotor (22) defining an internal chamber for receiving a multi-component fluid and a skimmer assembly (24) including a moveable buoy (28) having an orifice (32) fluidly connected to an access port for the rotor for selectively withdrawing separated fractions of the multi-component fluid. The multi-component fluid can be fed into the internal chamber before the rotor (22) can be rotated at a first speed to fractionate the multi-component fluid. A brake can be applied to the rotor to slow rotation of the rotor to a slower second speed or stop rotation of the rotor causing the solid and denser fluid fractions to settle on the bottom wall (44) of the rotor (22). The buoy (28) can have a specific gravity corresponding to a selected fraction such that the buoy floats on a surface of the selected fraction, wherein the fractions floating on the selected fraction can be withdrawn through the orifice (32).Type: ApplicationFiled: May 18, 2018Publication date: June 25, 2020Inventors: Randel E. Dorian, Matthew D. Landrigan, Kyle Kausch
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Patent number: 10441634Abstract: Methods of treating peripheral vascular disease comprising administering a protein solution site of a defect at least two proteins from the group IL-1ra, sTNF-RI, sTNF-RII, IGF-I, EGF, HGF, PDGF-AB, PDGF-BB, VEGF, TGF-?1, and sIL-1RII. The solution may also comprise white blood cells, platelets, concentrated bone marrow aspirate, and combinations thereof.Type: GrantFiled: December 8, 2017Date of Patent: October 15, 2019Assignee: Biomet Biologics, LLCInventors: Matthew D. Landrigan, Krista Toler, Jennifer E. Woodell-May, David L. Suter
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Publication number: 20180099026Abstract: Methods of treating peripheral vascular disease comprising administering a protein solution site of a defect at least two proteins from the group IL-1ra, sTNF-RI, sTNF-RII, IGF-I, EGF, HGF, PDGF-AB, PDGF-BB, VEGF, TGF-?1, and sIL-1RII. The solution may also comprise white blood cells, platelets, concentrated bone marrow aspirate, and combinations thereof.Type: ApplicationFiled: December 8, 2017Publication date: April 12, 2018Inventors: Matthew D. Landrigan, Krista Toler, Jennifer E. Woodell-May, David L. Suter
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Patent number: 9895418Abstract: Methods of treating peripheral vascular disease comprising administering a protein solution site of a defect at least two proteins from the group IL-1ra, sTNF-RI, sTNF-RII, IGF-I, EGF, HGF, PDGF-AB, PDGF-BB, VEGF, TGF-?1, and sIL-1RII. The solution may also comprise white blood cells, platelets, concentrated bone marrow aspirate, and combinations thereof.Type: GrantFiled: March 15, 2013Date of Patent: February 20, 2018Assignee: Biomet Biologics, LLCInventors: Matthew D. Landrigan, Krista O'Shaughnessey, Jennifer E. Woodell-May, David L. Suter
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Patent number: 9878011Abstract: Methods and therapeutic compositions for treating respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and devices for administering the therapeutic compositions. Methods for treatment include producing a protein solution, producing a concentrated bone marrow aspirate (cBMA), optionally combining the protein solution and cBMA to form an therapeutic composition, and optionally saturating the autologous therapeutic composition with hydrogen gas, and administering the therapeutic composition to a subject in need thereof. The present methods, compositions and devices are useful for treating COPD and the progression of COPD.Type: GrantFiled: March 15, 2013Date of Patent: January 30, 2018Assignee: Biomet Biologics, LLCInventors: Matthew D. Landrigan, Krista O'Shaughnessey, Jennifer E. Woodell-May
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Patent number: 9808487Abstract: Methods for transfusing blood to a mammalian subject. The method includes obtaining a unit of blood, rejuvenating the blood with an enhancement composition, measuring a level of 2,3-diphosphoglycerate in the blood, and delivering the blood to a subject.Type: GrantFiled: June 24, 2015Date of Patent: November 7, 2017Assignee: Biomet Biologics, LLCInventors: Alan Gray, Joel C. Higgins, Matthew D. Landrigan, Grant Cunningham
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Patent number: 9696242Abstract: A separation device that can include a separation tube or container that has a wall defining an internal volume into which a material can be placed is disclosed. The material can include a multi-component mixture or solution. A secondary tube or withdrawal cannula can be placed and/or moved within the tube to withdrawal a material form the tube.Type: GrantFiled: October 9, 2014Date of Patent: July 4, 2017Assignee: Biomet Biologics, LLCInventors: Trenton Walker, Matthew D. Landrigan, Michael D. Leach, Scott R. King, Randel Dorian, Richard W. Storrs
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Patent number: 9642956Abstract: A buoy or float can be positioned within a separation container to assist in a physical separation of components of a whole material positioned in the separation container. The buoy can be positioned within the container to move from between and separation a first end and a second end of the container substantially unaffected by a portion of the whole material, including a clotted portion thereof. A first port can be provided near the first end of the container for introduction of the whole material and a second port can be provided near the second end of the container for removal of at least a portion of a separated material.Type: GrantFiled: August 27, 2012Date of Patent: May 9, 2017Assignee: BIOMET BIOLOGICS, LLCInventors: Matthew D. Landrigan, Matthew Swift
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Patent number: 9239276Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.Type: GrantFiled: October 28, 2013Date of Patent: January 19, 2016Assignee: BIOMET BIOLOGICS, LLCInventors: Matthew D. Landrigan, Michael D. Leach, Joel C. Higgins
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Publication number: 20150366911Abstract: Methods for transfusing blood to a mammalian subject. The method includes obtaining a unit of blood, rejuvenating the blood with an enhancement composition, measuring 2,3-DPG concentration of the blood, and delivering the blood to a subject.Type: ApplicationFiled: June 24, 2015Publication date: December 24, 2015Inventors: Alan GRAY, Joel C. HIGGINS, Matthew D. LANDRIGAN, Grant CUNNINGHAM
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Patent number: 9103842Abstract: Methods for transfusing blood to a mammalian subject. The method includes obtaining a unit of blood, rejuvenating the blood with an enhancement composition, measuring 2,3-DPG concentration of the blood, and delivering the blood to a subject.Type: GrantFiled: March 15, 2013Date of Patent: August 11, 2015Assignee: Biomet Biologics, LLCInventors: Alan Gray, Joel C. Higgins, Matthew D. Landrigan, Grant Cunningham
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Patent number: 9078639Abstract: A bone marrow aspiration assembly including an outer cannula assembly, an inner cannula assembly, and a flexible seal. The outer cannula assembly includes an outer handle and an outer cannula defining a first passageway and including a plurality of first openings between a first end and a second end of the first passageway. The inner cannula assembly includes an inner handle and an inner cannula defining a second passageway and is configured to be received within the first passageway. The inner cannula includes a plurality of second openings between a first end and a second end of the second passageway. The flexible seal is mounted to the inner handle and positioned such that the seal contacts the outer cannula assembly when the inner cannula assembly is in cooperation with the outer cannula assembly to create a substantially airtight seal therebetween.Type: GrantFiled: December 21, 2011Date of Patent: July 14, 2015Assignee: Biomet Biologics, LLCInventors: Matthew D. Landrigan, James M. McKale
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Publication number: 20150104824Abstract: A separation device that can include a separation tube or container that has a wall defining an internal volume into which a material can be placed is disclosed. The material can include a multi-component mixture or solution. A secondary tube or withdrawal cannula can be placed and/or moved within the tube to withdrawal a material form the tube.Type: ApplicationFiled: October 9, 2014Publication date: April 16, 2015Inventors: Trenton WALKER, Matthew D. Landrigan, Michael D. Leach, Scott R. King, Randel Dorian, Richard W. Storrs
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Publication number: 20140271587Abstract: Methods and therapeutic compositions for treating respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and devices for administering the therapeutic compositions. Methods for treatment include producing a protein solution, producing a concentrated bone marrow aspirate (cBMA), optionally combining the protein solution and cBMA to form an therapeutic composition, and optionally saturating the autologous therapeutic composition with hydrogen gas, and administering the therapeutic composition to a subject in need thereof. The present methods, compositions and devices are useful for treating COPD and the progression of COPD.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Applicant: BIOMET BIOLOGICS, LLCInventors: Matthew D. LANDRIGAN, Krista O'SHAUGHNESSEY, Jennifer E. WOODELL-MAY
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Publication number: 20140271588Abstract: Methods of treating peripheral vascular disease comprising administering a protein solution site of a defect at least two proteins from the group IL-1ra, sTNF-RI, sTNF-RII, IGF-I, EGF, HGF, PDGF-AB, PDGF-BB, VEGF, TGF-?1, and sIL-1RII. The solution may also comprise white blood cells, platelets, concentrated bone marrow aspirate, and combinations thereof.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Inventors: Matthew D. LANDRIGAN, Krista O'SHAUGHNESSEY, Jennifer E. WOODELL-MAY, David L. SUTER
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Publication number: 20140257133Abstract: A bone marrow aspiration assembly including a cannulated introducer needle and an aspiration needle. The cannulated introducer needle is curved to approximate a natural curvature of an iliac crest. The aspiration needle includes apertures for aspirating bone marrow. The aspiration needle is configured to be received in, and extend from, the cannulated introducer needle to reach a bone marrow aspiration site in the iliac crest.Type: ApplicationFiled: May 19, 2014Publication date: September 11, 2014Applicant: Biomet Biologics, LLCInventors: Matthew D. Landrigan, James M. McKale
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Publication number: 20140212397Abstract: Methods for transfusing blood to a mammalian subject. The method includes obtaining a unit of blood, rejuvenating the blood with an enhancement composition, measuring 2,3-DPG concentration of the blood, and delivering the blood to a subject.Type: ApplicationFiled: March 15, 2013Publication date: July 31, 2014Inventors: Alan GRAY, Joel C. HIGGINS, Matthew D. LANDRIGAN, Grant CUNNINGHAM
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Patent number: 8728008Abstract: A bone marrow aspiration assembly including an outer cannula and an inner cannula. The inner cannula is moved only radially about a longitudinal axis thereof with respect to the outer cannula to selectively align inner openings of only one of distal, intermediate, and proximal opening groups of the inner cannula with outer openings of only one of distal, intermediate, and proximal opening groups of the outer cannula to permit aspiration therethrough.Type: GrantFiled: August 3, 2010Date of Patent: May 20, 2014Assignee: Biomet Biologics, LLCInventors: Matthew D. Landrigan, James M. McKale
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Publication number: 20140054246Abstract: A buoy or float can be positioned within a separation container to assist in a physical separation of components of a whole material positioned in the separation container. The buoy can be positioned within the container to move from between and separation a first end and a second end of the container substantially unaffected by a portion of the whole material, including a clotted portion thereof. A first port can be provided near the first end of the container for introduction of the whole material and a second port can be provided near the second end of the container for removal of at least a portion of a separated material.Type: ApplicationFiled: August 27, 2012Publication date: February 27, 2014Applicant: Biomet Biologics, LLCInventors: Matthew D. LANDRIGAN, Matthew SWIFT