Abstract: Preventing freezing in a heat exchanger can include passing first and second cooling fluids through the heat exchanger, monitoring a temperature and/or pressure of the second cooling fluid entering the heat exchanger, heating the second cooling fluid entering the heat exchanger by opening a valve when the monitored temperature and/or monitored pressure is below a trigger temperature and/or trigger pressure, and closing the valve when a condition is met. The first cooling fluid can have a first freezing temperature and the second cooling fluid can have a second, lower freezing temperature. Opening the valve can cause the second cooling fluid, in gaseous phase, to mix with the second cooling fluid, in liquid phase, upstream of the heat exchanger.

Abstract: A compound having one of the following structures of Formula (IV) or (V): or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R3, R4, R5 R6, R7, R8, R10, R11a R11b, R12a R12b, X, Y, and Z are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.

Abstract: A system includes sensors deployed along a vehicle pathway to detect the presence of a plurality of vehicles. An embodiment of a method for detecting speed may include generating from the sensors presence data of each of the plurality of vehicles and transmitting the detected presence data to a base station. The transmitting may include transmitting the detected presence data from the sensors to an access point and transmitting the detected presence data from the access point to the base station. The base station determines a speed of each of the plurality of vehicles. The speed may be determined at a periodic interval responsive to a predetermined distance between the sensors and a difference in the detection time of each of the plurality of vehicles at each of the sensors.

Abstract: A compound having one of the following structures of Formula (IV) or (V): or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R3, R4, R5 R6, R7, R8, R10, R11a R11b, R12a R12b, X, Y, and Z are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.

Abstract: Systems and methods for redundant storage among networked video cameras are described. Video data for a group of video cameras is received by a parity video camera. The parity video camera calculates parity across the peer video data, stores the parity data to one storage location and backup video data for the storage location to another storage location. In some examples, the storage locations are selected from among the non-volatile memory of the group of video cameras or another group of video cameras.

Abstract: Systems and methods for redundant storage among networked video cameras are described. Video data for a group of video cameras is received by a parity video camera. The parity video camera calculates parity across the peer video data, stores the parity data to one storage location and backup video data for the storage location to another storage location. In some examples, the storage locations are selected from among the non-volatile memory of the group of video cameras or another group of video cameras.

Abstract: The present invention provides radical crosslinked zwitterionic gels, methods of preparing the radical crosslinked zwitterionic gels, and methods of using the radical crosslinked zwitterionic gels for treating a wound.

Abstract: Compositions comprising an AhR agonist compound, such as indigo and/or an indigo derivative, such as indirubin and isatin, are described. Methods of treatment, including the treatment of ulcerative colitis, by administering the compositions are described. In an embodiment, compositions in the form of a solid amorphous dispersion of the AhR agonist are described.

Abstract: Compositions and methods for treating skin conditions, ailments or diseases, such as autoinflammatory skin diseases such as psoriasis, dermatitis, pyoderma gangrenosum, palmoplantar pustulosis, prurigo nodularis and/or hidradenitis suppurativa, are described. The compositions comprise an agent that modulates the aryl hydrocarbon receptor, in particular an agent that agonizes the receptor. In one embodiment, the agent is indigo or a derivative of indigo, such as indirubin.

Abstract: The present disclosure provides methods for purifying a solution comprising cantharidin and cantharidin-associated impurities. A method to purify the solution can comprise recrystallization or sublimation, for example. The purified cantharidin can be analyzed using a detection method comprising a stationary phase and one or more mobile phases.

Abstract: Compositions and methods for treating skin conditions, ailments or diseases, such as autoinflammatory skin diseases such as psoriasis, dermatitis, pyoderma gangrenosum, palmoplantar pustulosis, prurigo nodularis and/or hidradenitis suppurativa, are described. The compositions comprise an agent that modulates the aryl hydrocarbon receptor, in particular an agent that agonizes the receptor. In one embodiment, the agent is indigo or a derivative of indigo, such as indirubin.

Abstract: Provided is a multi-fiber system that undergoes new chemical bonds in response to mechanical manipulation and has self-adhesive properties based on specific chemical reactions.

Abstract: Compositions and methods for treating skin conditions, ailments or diseases, such as autoinflammatory skin diseases such as psoriasis, dermatitis, pyoderma gangrenosum, palmoplantar pustulosis, prurigo nodularis and/or hidradenitis suppurativa, are described. The compositions comprise an agent that modulates the aryl hydrocarbon receptor, in particular an agent that agonizes the receptor. In one embodiment, the agent is indigo or a derivative of indigo, such as indirubin.

Abstract: A system includes sensors deployed along a vehicle pathway to detect the presence of a plurality of vehicles. An embodiment of a method for detecting speed may include generating from the sensors presence data of each of the plurality of vehicles and transmitting the detected presence data to a base station. The transmitting may include transmitting the detected presence data from the sensors to an access point and transmitting the detected presence data from the access point to the base station. The base station determines a speed of each of the plurality of vehicles. The speed may be determined at a periodic interval responsive to a predetermined distance between the sensors and a difference in the detection time of each of the plurality of vehicles at each of the sensors.

Abstract: Compositions comprising an AhR agonist compound, such as indigo and/or an indigo derivative, such as indirubin and isatin, are described. Methods of treatment, including the treatment of ulcerative colitis, by administering the compositions are described. In an embodiment, compositions in the form of a solid amorphous dispersion of the AhR agonist are described.

Abstract: Compositions comprising an AhR agonist compound, such as indigo and/or an indigo derivative, such as indirubin and isatin, are described. Methods of treatment, including the treatment of ulcerative colitis, by administering the compositions are described. In an embodiment, compositions in the form of a solid amorphous dispersion of the AhR agonist are described.

Abstract: The present disclosure provides methods for synthesizing cantharidin and cantharidin derivatives.

Abstract: A system includes sensors deployed along a vehicle pathway to detect the presence of a plurality of vehicles. An embodiment of a method for detecting speed may include generating from the sensors presence data of each of the plurality of vehicles and transmitting the detected presence data to a base station. The transmitting may include transmitting the detected presence data from the sensors to an access point and transmitting the detected presence data from the access point to the base station. The base station determines a speed of each of the plurality of vehicles. The speed may be determined at a periodic interval responsive to a predetermined distance between the sensors and a difference in the detection time of each of the plurality of vehicles at each of the sensors.

Abstract: Systems, methods, and apparatus are provided that can reduce power consumption of memory controllers in response to memory command backlog in various situations. A data storage device includes a plurality of sets of non-volatile memory (NVM) devices, a central controller, and a plurality of channel controllers. Each channel controller is coupled to a distinct set of the plurality of sets of NVM devices. Each channel controller includes a command queue configured to store pending memory commands and provide backlog information. The central controller is configured to receive the backlog information of the command queues of the plurality of channel controllers, and adjust a clock frequency of the central controller and one or more clock frequencies of the plurality of channel controllers based on the backlog information such that the pending memory commands in each of the command queues are below a predetermined threshold level.

Abstract: A larger active camming device including a plurality of opposed camming lobes, a cam head, a retraction system, and a connection system. The cam head includes a stem end and two parallel axles coupled to the stem end. The retraction system is a unique system comprised of a trigger, flexible trigger wires, control horns, and torsion springs. The control horns couple the trigger to the camming lobes and are configured to reduce buckling and allow greater camming range. The retraction system can also include a retraction locking mechanism. The locking mechanism is used to store the cam in a retracted and locked position until it is needed by the climber. When needed, the climber can easily unlock and extend the camming lobes with one hand.