Patents by Inventor Matthew Gamboa

Matthew Gamboa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Site-specific integration of transgenes into human cells
    Patent number: 9932607
    Abstract: Methods for inserting a polynucleotide sequence into the genome of a human cell are provided. The present methods result in insertion of a polynucleotide sequence of interest into the H11 locus in the genome of a human cell. Also provided are nucleic acids that include sequences for integrating a polynucleotide sequence of interest into the H11 locus in the genome of a human cell. A transgenic human cell including site specific recombination sites at the H11 locus is also disclosed.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: April 3, 2018
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Michele Pamela Calos, Ruby Yanru Tsai, Fangfang Zhu, Matthew Gamboa, Alfonso P. Farruggio, Simon Hippenmeyer, Bosiljka Tasic, Birgitt Schüle
  • Site-Specific Integration of Transgenes into Human Cells
    Publication number: 20150140665
    Abstract: Methods for inserting a polynucleotide sequence into the genome of a human cell are provided. The present methods result in insertion of a polynucleotide sequence of interest into the H11 locus in the genome of a human cell. Also provided are nucleic acids that include sequences for integrating a polynucleotide sequence of interest into the H11 locus in the genome of a human cell. A transgenic human cell including site specific recombination sites at the H11 locus is also disclosed.
    Type: Application
    Filed: November 12, 2014
    Publication date: May 21, 2015
    Inventors: Michele Pamela Calos, Ruby Yanru Tsai, Fangfang Zhu, Matthew Gamboa, Alfonso P. Farruggio, Simon Hippenmeyer, Bosiljka Tasic, Birgitt Schüle