Patents by Inventor Matthew Goldstein
Matthew Goldstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240150277Abstract: The present invention includes compounds of formula (I) and methods for its preparation and treatment of disorders with activated peroxisome preoliferator-activated receptor gamma (PPARG), particularly cancer.Type: ApplicationFiled: August 31, 2023Publication date: May 9, 2024Applicants: Bayer Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.Inventors: Stephan SIEGEL, Knut EIS, Timo STELLFELD, Léa Aurelie BOUCHÉ, Elisabeth POOK, Joseph Peter BLUCK, Philip LIENAU, Constantia PANTELIDOU, Isabel Sophie JERCHEL-FURAU, Ulf BRÜEGGEMEIER, Sven CHRISTIAN, Detlev SÜLZLE, Anders Roland FRIBERG, Simon HOLTON, Christian LECHNER, Stefan KAULFUSS, Hanna MEYER, Douglas ORSI, Steven James FERRARA, Jonathan GOLDSTEIN, Matthew MEYERSON, Christopher LEMKE
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Publication number: 20240109850Abstract: The present invention includes compounds of formula (I) and methods for its preparation and treatment of disorders with activated peroxisome preoliferator-activated receptor gamma (PPARG), particularly cancer.Type: ApplicationFiled: August 31, 2023Publication date: April 4, 2024Applicants: Bayer Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.Inventors: Knut EIS, Elisabeth POOK, Ulf BRÜGGEMEIER, Adelaide Clara F. A. DE LEMOS, Sven CHRISTIAN, Isabel Sophie JERCHEL-FURAU, Ulrike RAUH, Nico BRÄUER, Timo STELLFELD, Anders Roland FRIBERG, Christian LECHNER, Stefan KAULFUSS, Hanna MEYER, Charlotte Christine KOPITZ, Steven James FERRARA, Jonathan GOLDSTEIN, Matthew MEYERSON, Christopher LEMKE, Timothy A. LEWIS
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Publication number: 20240067303Abstract: An electric snowmobile, has: a frame; a drive track assembly having a drive track and a sprocket; an electric motor mounted to the frame; and a transmission mounted to the frame, the transmission drivingly engaging the electric motor to the drive track, the transmission having an input drivingly engaged by the electric motor and an output drivingly engaging the sprocket, the transmission having a speed ratio defined as a rotational speed of the input to a rotational speed of the output, and wherein one or more of: a rotor-to-sprocket ratio ranging from 0.65 to 1.30, a rotor-to-transmission ratio ranging from 52 mm to 180 mm, a stator-to-sprocket ratio ranging from 0.20 to 0.58, and a rotor size-to-sprocket ratio ranging from 25 mm to 105 mm.Type: ApplicationFiled: August 26, 2022Publication date: February 29, 2024Inventors: Matthew Schroeder, Cyrille Goldstein, Amin Zabihinejad, Samuel Bruneau, Paul Achard
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Patent number: 11656048Abstract: An energy harvesting electronic primer (e-primer) system including smart ammunition with e-primer technology to enhance public safety from the discharge of a firearm by replacing conventional mechanical primers used for the activation of energetic materials with an electronic primer in center fire type ammunitions, grenades, bombs and other explosive devices wherein the ammunition includes an e-primer system having a firing pin, primer cup with a safety switch, antenna, piezo element, diode, capacitor, microcontroller, thermal wire, nanoenergetic and flash hole and radio transmitter circuitry wherein the mechanical force of the firing pin strikes a nanoenergetic material to activate the initial phase of an energetic train unless the e-primer is neutralized by a radio or acoustic signal captured by the antenna mounted within the ammunition where the radio signal includes a deactivation code to neutralize the ammunition. when located in a space specifically designed to receive the radio or acoustic signal.Type: GrantFiled: October 30, 2020Date of Patent: May 23, 2023Inventor: Zachary Matthew Goldstein
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Patent number: 11423195Abstract: A method is disclosed of providing a graphical user interface (GUI) for simulating target detection and recognition. The method includes providing a user entry area for receiving user entered ground truth attributes defining one or more respective simulated physical objects, and providing a user entry area for receiving user entered collection attributes defining one or more collections, each collection being a simulation of automated target recognition applied to simulated sensor output associated with simulated sensing of the one or more simulated physical objects. The method further includes simulating detection of the one or more simulated physical objects and recognition based on the ground truth attributes and the collection attributes, generating detection data about at least one detected object based on the simulated target detection, and displaying the detection data.Type: GrantFiled: September 17, 2018Date of Patent: August 23, 2022Assignee: Goodrich CorporationInventors: Christopher M. Jengo, Suhail Shabbir Saquib, Matthew Goldstein, Allan B. Liburd
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Patent number: 11403842Abstract: A simulator to simulate target detection and recognition is provided. The simulator includes a memory configured to store instructions and a processor disposed in communication with said memory. The processor upon execution of the instructions is configured to receive ground truth attributes defining one or more respective simulated physical objects and receive collection attributes defining one or more collections. Each collection is a simulation of automated target recognition applied to simulated sensor output associated with simulated sensing of the one or more simulated physical objects. The processor upon execution of the instructions is further configured to simulate detection of the one or more simulated physical objects and recognition based on the ground truth attributes and the collection attributes and output detection data about at least one detected object based on the simulation of target detection.Type: GrantFiled: September 17, 2018Date of Patent: August 2, 2022Assignee: Goodrich CorporationInventors: Christopher M. Jengo, Suhail Shabbir Saquib, Allan B. Liburd, Matthew Goldstein
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Patent number: 11393189Abstract: A method to simulate target detection and recognition is provided. The method includes receiving ground truth attributes defining one or more respective simulated physical objects and receiving collection attributes defining one or more collections. Each collection is a simulation of automated target recognition applied to simulated sensor output associated with simulated sensing of the one or more simulated physical objects. The method further includes simulating detection of the one or more simulated physical objects and recognition based on the ground truth attributes and the collection attributes, generating detection data about at least one detected object based on the simulated target detection, and outputting the detection data.Type: GrantFiled: September 17, 2018Date of Patent: July 19, 2022Assignee: Goodrich CorporationInventors: Christopher M. Jengo, Suhail Shabbir Saquib, Allan B. Liburd, Matthew Goldstein
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Publication number: 20220177840Abstract: The generation of antigen specific T cells by controlled ex vivo induction or expansion can provide highly specific and beneficial T cell therapies. The present disclosure provides T cell manufacturing methods and therapeutic T cell compositions which can be used for treating subjects with cancer and other conditions, diseases and disorders personal antigen specific T cell therapy.Type: ApplicationFiled: October 5, 2021Publication date: June 9, 2022Inventors: Marit M. VAN BUUREN, Divya Reddy LENKALA, Joost Huibert VAN DEN BURG, Jessica Kohler, Matthew GOLDSTEIN, Ed Fritsch, Renate DE BOER, Ton SCHUMACHER, Noor BAKKER
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Publication number: 20210386856Abstract: The present invention relates to neoplasia vaccine or immunogenic composition administered in combination with other agents, such as checkpoint blockade inhibitors for the treatment or prevention of neoplasia in a subjectType: ApplicationFiled: June 11, 2019Publication date: December 16, 2021Inventors: Robert Ang, Richard Gaynor, Matthew Goldstein
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Patent number: 11162072Abstract: The generation of antigen specific T cells by controlled ex vivo induction or expansion can provide highly specific and beneficial T cell therapies. The present disclosure provides T cell manufacturing methods and therapeutic T cell compositions which can be used for treating subjects with cancer and other conditions, diseases and disorders personal antigen specific T cell therapy.Type: GrantFiled: January 6, 2020Date of Patent: November 2, 2021Assignees: BIONTECH US INC., Stichting Het Nederlands Kanker Instituut—Antoni Van Leeuwenhoek ZiekenhuisInventors: Marit M. Van Buuren, Divya Reddy Lenkala, Joost Huibert Van Den Berg, Jessica Kohler, Matthew Goldstein, Ed Fritsch, Renate De Boer, Ton Schumacher, Noor Bakker
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Patent number: 10769005Abstract: A subsystem of a tactical information system is provided that includes a memory configured to store instructions and a processor disposed in communication with the memory. The processor, upon execution of the instructions is configured to receive first standardized entity messages that include target information from multiple automatic target recognition (ATR) systems, parse the first standardized entity messages to extract the target information, provide the extracted target information to a fusion algorithm for fusion processing that determines whether to fuse the target information from different ATR systems and fuses the extracted target information to generate fused target information about a single target when determined to do so, receive fused target information about the single target, if any, from the fusion algorithm, and generate a second standardized entity message that includes the fused target information about the single target.Type: GrantFiled: December 7, 2018Date of Patent: September 8, 2020Assignee: Goodrich CorporationInventors: Allan B. Liburd, Matthew Goldstein, Emily Seto
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Publication number: 20200183767Abstract: A subsystem of a tactical information system is provided that includes a memory configured to store instructions and a processor disposed in communication with the memory. The processor, upon execution of the instructions is configured to receive first standardized entity messages that include target information from multiple automatic target recognition (ATR) systems, parse the first standardized entity messages to extract the target information, provide the extracted target information to a fusion algorithm for fusion processing that determines whether to fuse the target information from different ATR systems and fuses the extracted target information to generate fused target information about a single target when determined to do so, receive fused target information about the single target, if any, from the fusion algorithm, and generate a second standardized entity message that includes the fused target information about the single target.Type: ApplicationFiled: December 7, 2018Publication date: June 11, 2020Applicant: Goodrich CorporationInventors: Allan B. Liburd, Matthew Goldstein, Emily Seto
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Publication number: 20200165567Abstract: The generation of antigen specific T cells by controlled ex vivo induction or expansion can provide highly specific and beneficial T cell therapies. The present disclosure provides T cell manufacturing methods and therapeutic T cell compositions which can be used for treating subjects with cancer and other conditions, diseases and disorders personal antigen specific T cell therapy.Type: ApplicationFiled: January 6, 2020Publication date: May 28, 2020Inventors: Marit M. VAN BUUREN, Divya Reddy LENKALA, Joost Huibert VAN DEN BERG, Jessica KOHLER, Matthew GOLDSTEIN, Ed FRITSCH, Renate DE BOER, Ton SCHUMACHER, Noor Bakker
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Publication number: 20200089981Abstract: A simulator to simulate target detection and recognition is provided. The simulator includes a memory configured to store instructions and a processor disposed in communication with said memory. The processor upon execution of the instructions is configured to receive ground truth attributes defining one or more respective simulated physical objects and receive collection attributes defining one or more collections. Each collection is a simulation of automated target recognition applied to simulated sensor output associated with simulated sensing of the one or more simulated physical objects. The processor upon execution of the instructions is further configured to simulate detection of the one or more simulated physical objects and recognition based on the ground truth attributes and the collection attributes and output detection data about at least one detected object based on the simulation of target detection.Type: ApplicationFiled: September 17, 2018Publication date: March 19, 2020Applicant: Goodrich CorporationInventors: Christopher M. Jengo, Suhail Shabbir Saquib, Allan B. Liburd, Matthew Goldstein
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Publication number: 20200089982Abstract: A method to simulate target detection and recognition is provided. The method includes receiving ground truth attributes defining one or more respective simulated physical objects and receiving collection attributes defining one or more collections. Each collection is a simulation of automated target recognition applied to simulated sensor output associated with simulated sensing of the one or more simulated physical objects. The method further includes simulating detection of the one or more simulated physical objects and recognition based on the ground truth attributes and the collection attributes, generating detection data about at least one detected object based on the simulated target detection, and outputting the detection data.Type: ApplicationFiled: September 17, 2018Publication date: March 19, 2020Applicant: Goodrich CorporationInventors: Christopher M. Jengo, Suhail Shabbir Saquib, Allan B. Liburd, Matthew Goldstein
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Publication number: 20200089822Abstract: A method is disclosed of providing a graphical user interface (GUI) for simulating target detection and recognition. The method includes providing a user entry area for receiving user entered ground truth attributes defining one or more respective simulated physical objects, and providing a user entry area for receiving user entered collection attributes defining one or more collections, each collection being a simulation of automated target recognition applied to simulated sensor output associated with simulated sensing of the one or more simulated physical objects. The method further includes simulating detection of the one or more simulated physical objects and recognition based on the ground truth attributes and the collection attributes, generating detection data about at least one detected object based on the simulated target detection, and displaying the detection data.Type: ApplicationFiled: September 17, 2018Publication date: March 19, 2020Applicant: Goodrich CorporationInventors: Christopher M. Jengo, Suhail Shabbir Saquib, Matthew Goldstein, Allan B. Liburd
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Publication number: 20090094046Abstract: A means and methods are provided to give a gift and simultaneously and unobtrusively record images and/or sound to capture the emotion and excitement of the gift recipient upon receipt of the gift and discovery of the gift-container contents. A gift container is combined with miniaturized video and/or audio recording technologies for use in conjunction with microelectronics and provides a means for recorded data transfer to external devices. Appropriate methods associated with related rentals, sales, and services to the consumer using the gift container are provided.Type: ApplicationFiled: February 7, 2008Publication date: April 9, 2009Inventors: Richard A. Hyman, David Hyman, Matthew Goldstein