Patents by Inventor Matthew H. McNeill

Matthew H. McNeill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apoptosis signal-regulating kinase 1 inhibitors
    Patent number: 8921358
    Abstract: The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) inhibiting compounds of the formula wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: December 30, 2014
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Edcon Chang, Matthew H. McNeill, Tracy Duong, Angie Vassar, Takehiro Hirano, Yoshito Terao
  • Thrombopoietin activity modulating compounds and methods
    Patent number: 7691895
    Abstract: Disclosed herein are compounds of Formula (I), (II), and (III) pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as thrombopoietin receptor modulators, and methods of treating disease by administering a compound of the invention to a patient in need thereof.
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: April 6, 2010
    Assignee: Ligand Pharmaceuticals, Inc.
    Inventors: Jyun-Hung Chen, E. Adam Kallel, Thomas Lau, Matthew H. McNeill, Todd A. Miller, Bao N. Nguyen, Richard J. Penulian, Dean P. Phillips, Daniel A. Ruppar, Lin Zhi, Jackline E. Dalgard
  • ACETYL COENZYME A CARBOXYLASE INHIBITORS
    Publication number: 20090005375
    Abstract: The present invention relates to acetyl coenzyme-A carboxylase (“ACC”) inhibiting compounds of the formula wherein the variables are as defined herein. In particular, the present invention relates to ACC1 and/or ACC2 inhibitors, compositions of matter, kits and articles of manufacture comprising these compounds, methods for inhibiting ACC1 and/or ACC2, and methods of making the inhibitors.
    Type: Application
    Filed: March 21, 2008
    Publication date: January 1, 2009
    Inventors: Edcon Chang, Matthew H. McNeill
  • THROMBOPOIETIN ACTIVITY MODULATING COMPOUNDS AND METHODS
    Publication number: 20080146594
    Abstract: Disclosed herein are compounds of Formula (I), (II), and (III) pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as thrombopoietin receptor modulators, and methods of treating disease by administering a compound of the invention to a patient in need thereof.
    Type: Application
    Filed: November 8, 2007
    Publication date: June 19, 2008
    Applicant: Ligand Pharmaceutical, Inc.
    Inventors: Jyun-Hung Chen, E. Adam Kallel, Thomas Lau, Matthew H. McNeill, Todd A. Miller, Bao N. Nguyen, Richard J. Penuliar, Dean P. Phillips, Daniel A. Ruppar, Lin Zhi, Jackline E. Dalgard
  • Thrombopoietin activity modulating compounds and methods
    Patent number: 7314887
    Abstract: Disclosed herein are compounds of Formula (I), (II), and (III) pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as thrombopoietin receptor modulators, and methods of treating disease by administering a compound of the invention to a patient in need thereof.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: January 1, 2008
    Assignee: Ligand Pharmaceuticals, Inc.
    Inventors: Jyun-Hung Chen, E. Adam Kallel, Thomas Lau, Matthew H. McNeill, Todd A. Miller, Bao N. Nguyen, Richard J. Penuliar, Dean P. Phillips, Daniel A. Ruppar, Lin Zhi, Jackline E. Dalgard